Use of arginine. Arginine tablets: mechanism of action

Taking arginine will help strengthen the body, since the drug combines multiple effects, having a direct effect on suppressing inflammation and regulating the functioning of blood vessels (also responsible for their growth and development). The instructions will warn against abuse and warn about side effects.

Composition and release form

Arginine is available in the form of capsules, tablets or injection solution. Tablets are sold in packs of 50. in a pack, capsules – 90 pcs. in a jar, solution for injection - in bottles of 20 ml. Ingredients:

The benefits and harms of Arginine

The amino acid arginine is a valuable substance that has a positive effect on the functioning of the cardiovascular system. It maintains optimal cholesterol levels in the blood, activates insulin production, stimulates the synthesis of growth hormone, reduces fat deposits and accelerates the healing process of wounds. The medicine has a beneficial effect on the functioning of the prostate, increasing blood flow to the genitals, increasing the amount of sperm produced, and creating optimal conditions for a stable erection. Harm from the use of Arginine has not been established.

A conditionally essential aliphatic amino acid cleanses the body of toxins resulting from protein metabolism. This leads to improved muscle trophism, accelerated recovery processes, lowered blood pressure, and intensified the flow of other amino acids into the muscles. Arginine:

• prevents oxidative processes;
• protects cells from aging;
• improves collateral blood flow;
• reduces the frequency of angina attacks.

L-arginine tones blood vessels, prevents the formation of blood clots, and is useful for kidney diseases, hypertension, arterial hypertension, and liver cirrhosis. Due to the amino acid, oxygen transport to tissues is improved, tumor growth slows down, and brain function is normalized. The substance dilates the blood vessels of the heart, which improves the functioning of the heart muscle, reduces strain, optimizes blood flow, and prevents the appearance of plaques and blood clots. Due to the amino acid, the functioning of the thymus gland improves. Other properties of arginine phosphate:

• formation of urea, glycogen, glucagon;
• providing nitrogen to the enzymatic system;
• increasing endurance (important for athletes), eliminating dystrophy;
• reduction in the frequency of angina attacks;
• enhancing the effect of antihypertensive drugs;
• participation in the production of hormones, somatotropin;
• stimulation of the production of serotonin - the hormone of joy, the neurotransmitter adrenaline;
• normalization of blood sugar levels in diabetes;
• acceleration of muscle recovery and tissue regeneration;
• reducing the number of free radicals;
• increasing muscle mass, burning fat.

Indications for use

Dietary supplement Arginine is used to compensate for the lack of L-arginine. Other indications for use, according to the instructions, are:

• prevention and complex therapy of cardiovascular diseases;
• overwork;
• physical and mental fatigue due to protein deficiency;
• asthenia during the recovery process after infectious diseases or surgery;
• hyperammonemia;
• metabolic alkalosis;
• complex treatment of viral hepatitis, immunodeficiency;
• type 2 diabetes mellitus;
• secondary hypertension;
• male infertility;
• delayed physical development;
• atherosclerosis;
• high blood pressure;
• chronic ischemia;
• slowdown in collagen production;
• cholecystitis, cholelithiasis;
• depression;
• anemia;
• anuria;
• gigantism;
• argininosuccinic aciduria;
• arthritis, arthrosis;
• tumors.

How to take Arginine

Encapsulated Arginine is taken 1 pc. (500 mg) twice a day with meals for a course of 2 weeks. Tablets are taken three times a day, 2-3 pieces. with food, but not more than 3 g per day. Oral solution or Arginine powder dissolved in water is taken 5 ml three times a day with meals. Children over 3 years old are given 3–10 mg twice a day, after 12 years old – 12–15 mg.

Bodybuilders are prescribed 3–9 g of arginine per day, but not more than 10 g. It is optimal to take the amino acid half an hour before and during training - this increases the level of nitric oxide, dilates capillaries, and increases tissue saturation with oxygen. While taking the medicine, the concentration of anabolic hormones, glucose, amino acids increases, and blood flow increases. Before bedtime, tablets are taken to stimulate the secretion of growth hormone.

Arginine solution is administered intravenously, dissolved in 100–200 ml of saline or 5% glucose solution. The infusion is carried out at a rate of 4 g per hour over a course of 5–10 days. Recommendations:

• The daily dose for adults is 4–8 g, but not more than 12.
• Newborns and children under one year of age are administered 200 mg/kg body weight.
• Children under 12 years of age are prescribed 100 mg/kg body weight.
• For diagnosis of growth disorders, adults are administered up to 30 g of the drug, children - 500 mg/kg body weight per day.
• To treat severe hyperammonemia, a shock dose of 600 mg/kg body weight is administered over 1.5 hours.

special instructions

Arginine is one of the most commonly used dietary supplements in bodybuilding. It stimulates muscles after training, starts regeneration processes, participates in muscle cell division, removes toxins, improves oxygen saturation of muscle tissue and creatine transport. To obtain a powerful effect, bodybuilders can combine the product with other sports supplements. Other special instructions from the instructions:

1. During pregnancy, the drug is used in the presence of pathologies - preeclampsia, intrauterine growth retardation.
2. If the drug is prescribed to patients with disorders of the endocrine glands, it is worth considering that it stimulates the secretion of insulin and growth hormone.
3. If the infusion rate is too high, the patient may develop irritation, redness, nausea, and vomiting.
4. Arginine is metabolized in the body to form nitrogen-containing compounds. A temporary increase in nitrogen levels leads to an increase in the load on the kidneys, especially if their function is impaired.
5. The drug contains chlorine ions, which should be taken into account when used in patients with electrolyte metabolism disorders.
6. The drug should be taken with caution during lactation.
7. Therapeutic doses of the drug do not affect the ability to concentrate and drive. If you receive high doses, you should stop driving.

Drug interactions

The combination of Arginine with Aminophylline can lead to an increase in the concentration of insulin in the blood. Against the background of renal failure, hyperkalemia may occur in patients who have taken or are taking potassium-sparing diuretics (Spironolactone). The substance is incompatible with Thiopental and potentiates the effect of nitric oxide donors (Sildenafil).

Side effects

If allergic to the components of the composition, patients may develop allergic skin reactions. Long-term use of tablets or capsules reduces immunity, which can activate herpes infection, increase excitability and disrupt sleep. Side effects of Arginine solution:

• headache, feeling hot;
• hyperkalemia, hyperchloremic acidosis;
• transient hypotension;
• nausea, vomiting, fever, diarrhea;
• tinnitus;
• numbness of the limbs;
• lethargy, irritation, mood changes.

Overdose

There have been no cases of Arginine overdose. Poisoning with the drug is impossible - this would require taking too large a dose. If this happens, you should consult a doctor for help.

Contraindications

The drug should be used with caution during pregnancy. Its contraindications, according to the instructions, are:

• intolerance to the components of the composition;
• pregnancy;
• herpes disease;
• schizophrenia;
• simultaneous intake of alcohol.

Terms of sale and storage

You can buy Arginine tablets without a prescription. They are stored out of the reach of children, protected from sunlight, at a temperature not exceeding 25 degrees for 2 years.

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Amino acids are constantly synthesized in the human body, but under the influence of unfavorable factors their production can be significantly reduced.

With insufficient formation of l arginine has the most serious consequences in the form of the development of certain diseases, however, with proper intake, it allows you to tirelessly support the nervous, immune and cardiovascular systems - guarantors of excellent human well-being.

Forms of release, composition and medical status of the product

The product is marketed in the form of tablets or capsules containing the amino acid. The purchase of the product is possible in pharmacy and sports chains without presenting an authorization document - a prescription. The status of a product with a valuable amino acid is classified as a dietary supplement, so the supplement is used in medicine only as a component of auxiliary therapy.

The main ingredient in these supplements is arginine, with additional third-party components that promote the absorption of the element. Silicon dioxide, magnesium salt, cellulose, stearic acid are essential components that are often included in products with arginine.

Variability of forms (concentration of active substance):

• 500 mg. This form of release is suitable for those who have not previously taken arginine-based products.
• 1000 mg. Capsules with this concentration are recommended for athletes.
• alternative options. Some manufacturers produce tablets with a concentration of 300, 600 and 900 mg, allowing you to choose the most comfortable dosage.

The price for l arginine varies depending on the number of tablets: a standard package (90 pieces) costs 1,700–2,000 rubles, options of 50 tablets cost 700–900 rubles. Arginine is produced by companies with different variable names from the following manufacturers: Altaivitamins Vazoton (350–380 rubles for 60 capsules), Now foods L-arginine (800–950 rubles for 250 capsules), Now Foods Arginine alpha-ketoglutarate 3500 (2100–2300 rubles for 180 tablets), Doppelgerz Arginine (820–990 rubles for 120 capsules), Elit-Pharm L-arginine (430–550 rubles for 50 capsules).

The natural decline in arginine production in adults begins at age 30.

The benefits and harms of taking arginine

Its role for blood vessels

Introducing arginine into the diet, which helps improve nitrogen balance, improves protein synthesis, which is necessary for increasing physical and mental abilities.

If there is an amino acid deficiency in the human body, then physical weakness, slow reaction and activation of processes that contribute to the loss of muscle mass are observed.

Other beneficial properties of the amino acid:

1. increased blood flow to all organs, including the brain;
2. increasing the elasticity of blood vessels and capillaries;
3. liver protection;
4. preventing blood clots;
5. cleansing the body of ammonia;
6. increased collagen production.

Additionally, the element helps reduce blood cholesterol and lower intraocular pressure. With periodic intake of the amino acid, the restorative function of the body also significantly increases - wounds and injuries disappear faster than without taking arginine.

Although there are benefits, harm also exists. In addition to individual intolerance, there are other conditions that are not compatible with taking arginine.

• colds on the lips (herpes);
• kidney and pancreas diseases;
• asthma;
• schizophrenia;
• hypotension.

In case of an overdose, the recipient may feel a sharp drop in blood pressure (although the property is useful for hypertensive patients), detect an increase in heart rate and feel pre-fainting.

The safe limit dosage of arginine is 6.8 g per day.

Instructions for use

The instructions included with the package contain comprehensive information on how to take arginine and how often it should be done.

Features of the intake for health (prevention):

• daily dose - 3 g;
• frequency of reception - three times;
• quantity - from 1 to 3 tables. (depending on the release form);
• break after the course - 1–2 months.

Full absorption of the amino acid is hindered by the intake of fatty foods, which should be consumed 5–6 hours after taking arginine. For children, the use of amino acids in tablets is not recommended by pediatricians, who believe that this component should be supplied to the developing body strictly through nutrition.

Indications for diseases

The doctor can prescribe an amino acid, regardless of the patient’s passion for sports or weak physical activity. In the presence of illnesses, the instructions for use indicate the period for taking arginine, usually no more than a 14-day period.

Amino acids have been proven to help with:

• insulin-dependent diabetes mellitus;
• cirrhosis and fibrosis of the liver;
• viral hepatitis;
• cholelithiasis;
• atherosclerosis.

In adolescence, it is rational to give the amino acid only for short stature and cystinuria.

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What is the drug "L-Arginine"? You will learn the answer to this question from the materials in this article. In it we will tell you about why this remedy is needed, what patients say about it, how it should be taken, and so on.

Composition, packaging and form

The drug "L-Arginine" goes on sale in the form of capsules. They are packaged in glass jars and cardboard packaging, respectively.

This drug contains an active substance such as l-arginine. As additional ingredients, it contains microcrystalline cellulose, hydroxypropyl methylcellulose and magnesium stearate.

Features of the drug

L-Arginine is an essential amino acid for children and conditionally essential for adults. This substance is produced in the human body, but in insufficient quantities for its full functioning. This element plays a special role in metabolism. It also enhances the production of somatotropin (or so-called

Pharmacological properties

What properties does the drug “L-Arginine” have? The instructions say that this amino acid is the main source of production, which is a powerful vasodilator and neurotransmitter.

The action of the medication is aimed at maintaining optimal cholesterol concentrations in the blood. This has a beneficial effect on the functioning of blood vessels and the heart.

In representatives of the stronger sex, while taking the drug "L-Arginine", the volume of seminal fluid increases, and the blood flow to the penis increases. This effect of the drug creates optimal conditions for a stable and long-lasting erection, and also contributes to the normal condition of the prostate gland.

What functions does it perform?

"L-Arginine", the price of which is indicated below, performs many different functions in the human body. Let's look at some of them:

Indications for use

Why do you need the drug "L-Arginine"? Reviews from experts say that this product is recommended for use as an additional source of the amino acid of the same name.

This medication is used as part of complex metabolic therapy, as well as for the prevention of various diseases of internal organs. In addition, the drug in question is able to compensate for the deficiency of nutrients in the body of healthy people who lead an active lifestyle.

Replenishing the amino acid l-arginine is extremely important for people who:

• regularly suffer from nervous disorders, as well as vascular and heart diseases, dystrophy, anemia and epilepsy;
• recovering their physical condition after long-term adherence to a therapeutic diet or substance abuse.

It should also be noted that one of the properties of l-arginine is the ability to increase the level of creatine in muscle tissue. This makes it advisable to use this drug in bodybuilding.

Contraindications for use

The drug "L-Arginine" is contraindicated for:

• herpes;
• individual intolerance to essential substances;
• pregnancy and breastfeeding;
• schizophrenia or other mental illnesses.

According to expert reviews, patients who have been diagnosed with cancer, as well as children during the period of active growth, should refrain from taking this drug. The last prohibition is explained by the fact that the amino acid has a direct effect on growth hormone. Therefore, it can provoke unwanted gigantism.

Careful reception

With extreme caution, the drug "L-Arginine" is prescribed to people with diabetes mellitus and patients who lack glucose tolerance. In the latter case, taking the drug may cause a hormonal shift, which will lead to an increase in the concentration of glucose in the blood.

Daily intake of the drug in an amount of 1 g for two weeks does not cause negative reactions in these groups of patients. At the same time, the amino acid itself is quite gently included in the metabolic processes occurring in the body.

It should also be noted that with extreme caution this remedy is indicated for use by people with kidney pathologies and impaired electrolyte balance.

Methods of application

How to take L-Arginine? According to the instructions, the daily dose of this drug for an adult is 3 grams. It is divided into 3 doses.

The use of capsules should coincide with meals. The duration of therapy is 2-4.5 weeks. A repeat course is possible after 30-60 days.

How to take it for bodybuilding?

For athletes, the daily dose of this drug is 3-9 g. Despite the fact that high dosages give a pronounced result, experienced bodybuilders do not recommend using more than 10 g of medication per day, as this can cause nausea, hypotension, vomiting, diarrhea or weakness.

Some experts recommend calculating the dosage of the drug yourself. To do this, you must adhere to the formula: 115 mg per 1 kg of weight. If such use causes at least one of the above phenomena, then the dose is reduced.

L-Arginine capsules should be taken with plenty of liquid. Let's take the drug together with creatine.

This product should be used immediately before training (60 minutes before the start). After an hour, the level of nitric oxide becomes sufficient for the muscles to begin to be saturated with oxygen, anabolic hormones and amino acids.

It is advisable to take the drug on an empty stomach. Under no circumstances should it be combined with fatty foods, as this will impair its absorption and negatively affect the effectiveness of the medication.

Experts say that for complete absorption of the amino acid, at least 5 hours must pass since the last time you consumed fatty foods.

Drug price

“L-Arginine” at the pharmacy (50 capsules) can be purchased for 850 rubles. When purchasing 90 capsules, you will have to pay about 1,800 rubles.

Arginine is a non-essential amino acid that helps the body cleanse itself of toxins and impurities and keeps the body in good shape. Our body produces this component itself, but sometimes it is not enough. This is why bodybuilders choose supplements with this component. But arginine can be beneficial not only for athletes. Let's find out who else might need it and why.

Beneficial features

Arginine is taken in order to:

• remove toxins and waste from the body;
• enrich the digestive system with nitrogen;
• improve the functioning of the cardiovascular system;
• help the production of hormones, including the hormone of happiness (serotonin);
• improve liver function;
• normalize sugar levels.

Our body can do all this itself by producing arginine. But there are times when this process is impossible - for example, during illness.

Important! There are many factors that influence the production of thisamino acids - age, gender, weight, bad habits, diet, genetic characteristics. Therefore, older people are often advised to take additional arginine.

For men

This amino acid is important for the male body, as it affects sexual life. Thus, a normal amount of arginine in the body increases sexual desire - with its help, blood vessels dilate and blood flow to the genitals increases. It also serves to protect the genitourinary system from inflammation and various diseases. In addition, fertility, namely the quality and motility of sperm, depends on this substance. It also increases performance and endurance.

For women

Improving sexual activity in women also depends on the level of arginine in the body. It also affects beauty - skin, nails, hair become better under the influence of the amino acid. Arginine is credited with a rejuvenating effect - the action of growth hormone is enhanced, which slows down aging. At the same time, the skin becomes noticeably more elastic.

For children

A deficiency of this amino acid can lead to a stop or deterioration in the child's growth. However, the use of additional substances only necessary if there are indications and advice from a doctor- otherwise, oversaturation with amino acids in the active period of growth will lead to gigantism.

Most often it is prescribed to teenagers when they experience hormonal imbalances that can negatively affect their health.

Did you know? To form 5 thousand proteins in the human body, 22 amino acids are needed.

In bodybuilding

In this area, this additive is used most often and most of all, and all because it helps bodybuilders build muscle mass, while fat will decrease. The substance also helps restore strength after hard training, and in case of injuries, accelerates their healing. However, there are still no facts that confirm all the positive properties of this substance. There is also reason to believe that there is no point in taking it without additional strong nitrogen donors.

For hair

Arginine helps restore hair from the inside- The supplement will be especially useful for severe hair loss. Since the amino acid dilates blood vessels, blood flow to the scalp is significantly improved, thereby accelerating hair growth.

The amino acid is included in many professional hair care products, as it reduces the effect of negative factors on the hair. It will be able to protect hair from the constant influence of dye and elevated temperatures (curling irons, hair dryers, in countries with hot climates).

Harm

Abuse of arginine can lead to negative consequences for the body. This only applies to cases where the substance is taken intentionally in the form of a medicine and without a doctor’s prescription. No harm will happen if the amino acid is produced in the body itself by eating the right foods.

People who have undergone heart surgery or are simply prone to diseases of this organ should avoid taking additional medication. There are also studies that indicate the substance is harmful for asthmatics. The sudden development of atherosclerosis can also cause the supplement to be taken in large quantities.

Important! Under no circumstances should you take arginine with coagulants (bleeding may occur).

People with hemophilia and diabetes should not use the substance without the knowledge of a doctor.

Contraindications and side effects

With prolonged and improper use of arginine, the following side effects may occur:

• deformation of joints and cartilage;
• tissue compaction;
• the appearance of abdominal pain, diarrhea (indigestion is common);
• weakness, nausea;
• decrease in blood pressure.

It is also worth considering that not everyone can take this supplement - It is worth giving up arginine in the following cases:

• when there are nervous disorders (even minor ones);
• during pregnancy and breastfeeding;
• children during the period of active growth;
• in case of individual intolerance to the drug.

Therefore, you need to take the substance only after a doctor’s prescription and following a certain dosage.

Indications and symptoms for use

Taking arginine is recommended for those who engage in heavy physical activity. There are also the following indications:

• cirrhosis and fatty liver degeneration;
• kidney diseases;
• arthritis, arthrosis;
• infertility;
• benign and malignant formations;
• depression.

Instructions for use, portion

The portion depends on the dosage of the amount of arginine in each capsule of the drug. The most common tablets are 500 mg and 1000 mg of amino acid. There are also powders and liquid suspensions.

Important! It is impossible to exceed the norm of arginine per day (3 g) - an overdose will lead to side effects.

Three 500 mg tablets per day are enough. But for bodybuilders, the dose is increased to 9 g per day. However, beginners should start with minimal doses and gradually increase them.

For athletes, the following calculations are accepted: 115 mg per 1 kg of weight. Take 40 minutes before meals or before training. But it is possible both during sports and after, only the effect will be a little worse.

Products containing arginine

If we are not talking about athletes, then it is better to replenish the amino acid naturally - with proper nutrition.

It is important to eat beef or pork, as well as sea and river fish, at least at one meal.

Dietary supplement L-arginine

Most often, arginine is taken as a separate supplement. with the prefix “L” in the name. In the right doses, it helps the heart function, improves blood vessels, lowers cholesterol, and promotes weight loss. Each package of the drug contains instructions for use with the dosage of the amino acid. A course of taking a dietary supplement helps:

• increase the level of growth hormone (growth) in the body;
• improve mood, increase performance;
• help teenagers who have problems with growth;
• heal wounds, sprains or fractures;
• help the kidneys cleanse the body;
• normalize the timing of puberty in children;
• improve potency.

Did you know? In 2000, they wanted to make bodybuilding an Olympic sport, but this did not happen, and disputes on this issue are still ongoing.

So, we found out that only supporting the natural level of arginine in the body through proper nutrition will help you avoid taking additional medications. However, if the need to increase the amount of this amino acid does arise, special nutritional supplements will help normalize metabolic processes and improve well-being.

L-arginine

Compound

1 capsule of L-arginine 180 contains 0.18 g of L-arginine. Auxiliary components: gelatin, MCC, magnesium stearate.

1 capsule of L-arginine 500 contains 0.5 g of L-arginine. Auxiliary components: gelatin, MCC, magnesium stearate.

1 capsule of L-arginine 750 contains 0.75 g of L-arginine. Auxiliary components: gelatin, MCC, magnesium stearate.

pharmachologic effect

The active component of the capsules is an aliphatic amino acid, which is classified as conditionally essential. Arginine is a NO donor and acts as a carrier. The substance improves the supply of enzymatic systems with nitric oxide, takes part in transamination reactions, and enhances the cleansing of the body from accumulated protein metabolic products.

Due to these actions, the following effects are observed when taking arginine-containing capsules: improving muscle trophism, accelerating recovery processes, improving erectile function, lowering blood pressure, improving the flow of other amino acids into muscle tissue.

The drug prevents the development of oxidative stress, protects cells from aging, reduces the formation of pathological (“bad”) cholesterol, increases collateral blood flow, helps reduce the frequency of angina attacks, increases the production of growth hormone, and increases endurance.

Indications for use

The drug L-arginine is prescribed for:
- viral hepatitis, unspecified;
- immunodeficiency states;
- physical activity;
- increased mental stress;
- non-insulin-dependent diabetes mellitus;
- secondary hypertension;
- delayed physical development;
- atherosclerosis;
- male infertility;
- insufficiency of genital reaction;
- essential hypertension;
- chronic ischemic heart disease;
- liver fibrosis;
- cholelithiasis;
- cirrhosis of the liver;
- asthenic conditions;
- cholecystitis.

Contraindications

The drug L-arginine is not prescribed for:
- hypersensitivity to L-arginine;
- pregnancy;
- herpetic infection;
- lactation;
- schizophrenia.

The drug L-arginine is prescribed with caution for:
- electrolyte imbalance;
- anuria (lack of urine);
- kidney pathologies.

Pregnancy

During pregnancy, L-arginine is contraindicated for use.

Drug interactions

No interactions with other drugs have been recorded.

Overdose

Exceeding the therapeutic dosage with signs of poisoning is unlikely, since this requires taking ultra-high doses of L-arginine.

Release form

The drug L-arginine is available in capsules. The packaging is as follows:
- 30 capsules/pack;
- 50 capsules/pack
- 60 capsules/pack;
- 90 capsules/pack;
- 100 capsules/pack;
- 120 capsules/pack;
- 250 capsules/pack.

Storage conditions

The storage temperature for L-arginine capsules is 10-25 degrees Celsius. The shelf life of capsules of all dosages is 2 years.

Active substance:

arginine hydrochloride

Additionally

If asthenia increases during therapy with L-arginine, the latter is discontinued.
For the full effect of therapy, it is necessary to normalize rest and sleep patterns, and abstinence from alcohol and psychostimulant drugs is indicated.

Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.