A growth hormone Today it is quite popular among professionals and sports fans. However, recently they have increasingly begun to talk about the side effects and dangers of using this drug, and the information is quite contradictory. Some experts consider growth hormone one of the most effective means for prolonging life, others argue that it is very harmful to our body. Let's try to understand this controversial issue!
The mechanism of action of growth hormone.
A growth hormone, or somatotropin, is a protein that consists of the 191st amino acid. The production and secretion of this hormone occurs in the anterior lobe of the pituitary gland (in the endocrine gland). By the way, of all the existing pituitary hormones, growth hormone is produced in the largest quantity, and this process lasts throughout a person’s life (after 20 years, the production of growth hormone begins to decrease by 15% per decade). The basal level of growth hormone reaches its maximum in early childhood, and peak secretion occurs during adolescence (puberty, intense linear growth).
Main functions of growth hormone.
Having a direct effect on the endocrine glands, somatotropin accelerates the production of a number of growth factors and muscle mass, and also actively regulates the metabolism of human bone tissue.
Growth hormone inhibits enzyme activity, which have a destructive effect on amino acids, regulates collagen synthesis in bone tissue, skin and other tissues and organs. Causes an increase in the size and number of cells of the thyroid gland, adrenal glands, liver, gonads, thymus gland and muscles.
Growth hormone enhances fat breakdown, as a result of which the concentration of fatty acids in the blood increases, which suppress the effect of insulin on membrane glucose transport.
Physiological effects of growth hormone.
Growth hormone prevents the development of a large number of destructive processes in the human body and stimulates restoration ones. Many authoritative scientists claim that under the influence of growth hormone, the body rejuvenates by 10-20 years:
- the skeletal system is strengthened;
- fat deposits are converted into muscle;
- immunity is strengthened;
- mental abilities increase;
- blood cholesterol levels decrease;
- sexual activity increases.
Dosages.
Growth hormone is the strongest active drug for active growth of muscle mass and rapid reduction of fat deposits. But in order to achieve the desired results from taking this drug, a number of conditions are required, which not many people can adhere to (a fairly strict schedule of nutrition, training and injections). So, what is a growth hormone course? Of course, the course of the drug and its dosage depend on the severity of physical activity and the type of sport, for example, dosages for track and field athletes reach 8 units per day, which is insufficient for an effective gain of muscle mass for a weightlifter.
For bodybuilders, the dosage should be at least 12-16 units, and the course duration should be at least 3 months. It is recommended to take growth hormone in large dosages for one simple reason: the receptors quickly get used to the drug, so you should not inject it for a long time. After a course of therapy, a break equal to the length of the course is required.
Of course, growth hormone is not prohibited from being taken for 6 months or more, but only in small dosages of 2-4 units per day. However, it is almost impossible to achieve hypertrophy and hyperplasia of muscle cells with this regimen.
Anabolic effect of growth hormone and related drugs.
Your goal is hyper growth of muscle mass. For such a process, your body will need maximum stimulation, and growth hormone alone will not cope. Complex therapy is required, including drugs that can not only enhance the effect of growth hormone, but also ensure the safety of your body. There is a certain regimen of drugs: growth hormone - anabolic and androgenic steroids - insulin - thyroid hormones. Let's look at each drug separately.
Androgenic steroids have powerful anabolic properties and significantly enhance muscle cell hypertrophy, so their inclusion in the complex is mandatory. Steroids will also stimulate cell hyperplasia, which will lead to faster results.
Insulin is also a mandatory drug in the complex, especially if the dosages of growth hormone are really high. Insulin will ease the load placed on the pancreas, which, under the influence of growth hormone, enhances its work and quickly depletes its reserves, and will also accelerate the growth of muscle cells. It is recommended to take 6-8 units of insulin before each meal.
Thyroid hormones help accelerate metabolism and stimulate tissue growth. The inclusion of thyroid hormones in the cycle will weaken the effect of growth hormone on the function of the gland (the size of the thyroid gland may increase). It is important to know that the use of growth hormone in large dosages can lead to changes in the functions of the thyroid gland (the development of hypothyroidism). Athletes using rather large dosages of growth hormone should take triiodothyronine (thyroid hormone) 50 mcg per day in two doses. However, large dosages of triiodothyronine are not recommended, as this will contribute to the opposite effect, i.e. loss of muscle mass.
What are the concerns?
Growth hormone, being an anabolic agent, promotes more intense metabolic processes and the production of free radicals in the body, which in turn leads to a shortening of life and the occurrence of a host of diseases: heart attack, stroke, cancer, etc.
When using growth hormone, side effects may occur such as nausea, headache, hyperglycemia, increased intracranial pressure, development of diabetes mellitus, excessive growth of cartilaginous bones, which leads to enlargement of facial features and enlargement of the lower and upper jaw.
To avoid local reactions, subcutaneous injection sites should be changed, as lipoatrophy, the burning of adipose tissue, may develop over time. With open growth zones (up to 25 years), the fact of linear body growth cannot be ruled out.
In custody.
Remember that you should not start a course of growth hormone without auxiliary medications - otherwise you will not only not achieve the desired results, but will also develop a number of chronic diseases. The dosage and duration of use in this case are critical. That's why, be careful and trust only experienced specialists!
It is practically the main reason that modern athletes look simply incomparable. As for all athletes in general, until the end of the 80s of the last century, none of the professionals knew anything about this. Everyone has long known that the use of steroids for bodybuilders is an integral part. But in this sense, growth hormone for muscle growth is a completely special topic, since even now, due to the too high price, not everyone can afford it. The quality is worth it though. At the same time, do not forget that this is an absolutely legal drug, unlike some types of steroids. This hormone has virtually no side effects that could lead to problems associated with the body. But only the right technique can provide a good result that will last for a long time.
At its core, it is a natural hormone that does not interfere with any body function, making it one of the most effective drugs that can help you achieve your goals.
Relation to the drug
In the sports community there are quite contradictory opinions regarding this drug - from enthusiastic exclamations to dismissive caution. This is due to the fact that any innovation is doomed to either success or failure. Unfortunately, the latter turned out to be the case with this drug, but this is not because of its ineffectiveness, but because the muscle growth hormone - somatotropin - is absolutely useless for some athletes, while for others it is a real panacea. Moreover, more than half of the athletes who used this hormone did so incorrectly. Effectiveness can only be achieved through trial and error, but given the cost of this drug, not everyone can afford it.
Proper use of the drug is necessary not so much in order to save your money. Rather, it is used to actually get the worthy result that the athlete is going for. The effectiveness of the drug depends not only on correct use, as some individual parameters may influence this.
Professional medical research
Biology will help you understand in more detail its effect on the body. Growth hormone, which was administered to patients, showed rather mixed results. The largest and most fundamental study that made a big splash was conducted by Dr. Rudman, who subsequently published the results in a medical journal on July 5, 1990. Based on the data obtained, the scientist managed to increase muscle mass in the subjects by 8.8% within 6 months, and this without physical activity. A loss of subcutaneous fat of 14.4% was also recorded without dieting or dietary changes. Although his report reported other positive benefits, no one else was able to achieve similar results. Whether this was due to the high level of professionalism of the doctor and his dedication to the topic, or whether the data was fabricated, no one knows for sure.
Types of growth hormone
Somatropin is a human growth hormone. Peptides are the basis of somatotropin, which is due to complete identity with the same amino acid sequence as the original one produced by the body. Somatropin is an extract from the pituitary gland, which was previously obtained from corpses, but this method is currently prohibited. Nowadays, human growth hormones are produced using genetically modified bacterial cells. In this case, the initial product obtained in this way is no different at all from the one originally created by the hypothalamus. It is designated rHG (recombinant growth hormone), but it is often called simply somatropin, or somatrem.
Natural secretion of growth hormone
Human growth is determined by the presence of somatotropin in the body. Thus, in a man’s blood its content is at the level of 1-5 ng/ml. But this indicator is not even an average, because throughout the day it changes and can reach 20 or even 40 ng/ml. This variation depends on individual characteristics, and if a person with the maximum level of hormones is introduced into the body with an additional portion, then, most likely, he will not feel much of a difference, and it will not be visible on the physical level either. By the way, the “folk method” for determining a large number of hormones still works. So, they look at a man’s feet and palms: their size should be much larger than the average. This is the genetic predisposition of any person. With all this, this method cannot be called the only correct one, since there are exceptions to the rules that do not in any way connect the size of individual body parts with the level of the hormone. Everything is individual in each individual case.
What regulates the natural secretion of growth hormone?
The endocrine gland, located at the base of the brain and influencing the growth, development, and metabolism of the body, is responsible for the process.
The level of growth hormone is controlled directly by the hypothalamus. By the way, he is the main controller in the case of the genitals. The amount of growth hormone and its need for the body is determined by two peptide hormones:
- Somatostatin.
- Somatoliberin.
Thus, in case of urgent need, they go straight to the pituitary gland. Growth hormone begins to be produced faster due to micropulse signals, but it can be increased using ordinary manipulations:
- peptides;
- somatoliberin;
- ghrelin;
- androgen secretion;
- healthy sleep;
- physical training;
- large amounts of protein.
Using such methods, you can increase the natural concentration of growth hormones by at least three, or even five times, but do not forget that only a reasonable combination of hormones, training and sleep patterns can provide good results.
What can he do?
The action of hormones affects human growth, which is why they have such a name. In addition to stimulating muscles, there are also positive effects on a number of other areas of the body:
- improves lipid levels;
- normalizes metabolic processes;
- sexual activity increases;
- catabolic processes in muscles are inhibited;
- joints and ligaments are strengthened;
- the process of fat burning is enhanced;
- accelerates the growth of young people (up to 25 years);
- increases the supply of glycogen depot in the liver;
- increases skin tone;
- quickly heals body wounds and regenerates new tissue;
- increases the size and number of cells of the liver, gonads and thymus glands.
Hormones: table regarding age
Growth hormone peaks around age 20. After this, secretion declines by an average of 15% for 10 years.
At different time periods of life, the concentration of somatotropin changes. In any case, the older you get, the less hormones are produced in the body. The table clearly shows the average trend of decrease in somatotropin relative to life. Thus, it becomes clear that the best age to take care of yourself and your body will be precisely the period from 15 to 25 years, and it is best to do it from early youth. In other words, “muscle building” will be more productive precisely during the most active periods of hormone production. But at the same time, you should not understand this in such a way that after 25 years no one has a chance to visit the gym and see the effect of training, it’s just that, most likely, you will have to make more efforts.
It is also worth adding that the secretion of growth hormone has its peaks during the day. The peak occurs every 4-5 hours, and the most intense production begins at night, approximately 60 minutes after falling asleep.
The production mechanism occurs as follows. The hypothalamus gives a command to the pituitary gland, which, in turn, begins to synthesize somatotropin. The hormone enters the bloodstream and is sent to the liver, where it is converted and becomes somatomedin. It is this substance that enters directly into muscle tissue.
Field of application in sports
Human growth hormones are widely used by athletes and athletes in particular in 4 areas:
- kit ;
- the fastest possible healing of joints that have been injured (precisely due to the fact that the hormone is effective for healing tendons, it is actively used not only in strength training, but also in athletics, tennis and football, where damage to the Achilles is quite common);
- burning excess fat mass;
- Help for athletes whose growth hormone begins to fall due to age-related changes.
Frequency of injections
Human growth hormone will only be effective if taken correctly. Somatropin was previously administered by injection 3 times a week, but soon specialists began to give injections every day in order to increase its effectiveness and at the same time reduce negative aspects. Scientists were still able to put an end to many years of controversy over the correct use of the hormone. The most effective injection is considered to be every other day. It is thanks to this practice that it was possible not only to qualitatively increase the level of effectiveness, but also to ensure that the sensitivity of the receptors did not decrease, regardless of how long the course of treatment was.
It is worth noting, however, one nuance: the practice of injections every other day gives good results only when the athlete’s diet is not cut, and the athlete himself receives the required amount of calories while gaining weight. In the pre-competition period, daily injections are recommended. This is due to the fact that the caloric content of food at this moment decreases.
The best time for injections varies on average at 1-2 hours before or after physical activity. If the training takes place late in the evening, then it is necessary to slightly adjust the course of taking hormones: for example, the first injection is given in the morning, and the second - a couple of hours before the start of the exercises.
As experts assure, for the best results during a course of taking hormones, it is best to completely adjust your usual training regimen and start going to the gym every other day, along with taking the drug. Naturally, this is only relevant during “working for mass”.
The active time of the hormone is called the half-life and averages from 2 to 4 hours. Despite the fact that this is not the half-life of the drug in the classical sense, the most active phase is observed precisely at this time. This is due to the fact that after 4 hours the drug stops suppressing its own secretion of growth hormone, but the level remains elevated for about 14 hours in a row. Based on this, it is not recommended to inject before bedtime, since the level of self-secretion is most active in the first hour of sleep. But it is also worth noting the fact that when the injection is administered late in the evening, sleep becomes stronger and deeper. Also during this period, burning of subcutaneous fat occurs much more intensely, so the question of what time to give injections becomes an individual question based on specific goals and objectives.
Side effects
With all the positive and unique aspects, growth hormone for muscle growth also has several undesirable side effects, which can manifest themselves in increased blood pressure, disruption of the thyroid gland, an increase in the size of the kidneys and heart, and hypoglycemia. In the case of long courses with a large dosage, there may be a risk of rapid development of diabetes in those athletes who have a genetic predisposition to this disease, or who already have it in the initial stages.
Particular attention is paid to the hormone that reduces insulin activity. Thus, it seems to be able to warn of an impending hypoglycemic coma. Any athlete knows that as soon as blood sugar levels decrease, the secretion of growth hormone immediately increases. But at a time when an athlete uses a high-calorie diet while gaining weight, the hormone also provokes a large release of insulin. Thus, the risk of hypoglycemia increases several times. Prolactin in the blood may also increase, but there is no point in seriously fearing this, because no more than 1/3 of athletes are sensitive to it. But even if it does occur, it can be easily dealt with with bromocriptine. The last of the possible actual side effects can be considered “tunnel syndrome,” which is caused by a pinched nerve in the carpal tunnel.
By the way, about the last one. A rather “interesting” side effect of using growth hormone is this so-called “tunnel syndrome”. This disease is typical for those who work a lot at the computer, and is a neurological disease manifested by prolonged pain and numbness of the fingers.
Once again about genetic differences
Once again, it is worth recalling that growth hormone for muscle growth affects everyone differently. Some athletes do not feel any effect on the body at all, due to the fact that antibodies are not formed, but for other athletes this is a real panacea. So, there is a noticeable increase in weight or the fat-burning effect of the substance is manifested. One interesting study showed that the response to this growth hormone directly depends on
Growth hormone and anabolic steroids
It is worth remembering the following: in order to get rid of excess fat or increase body weight, it is not enough to take only growth hormone. In this case, steroids will be an excellent supplement. Most relevant with somatotropin is the use of testosterone, special drugs “Stanozol”, “Trenbolone” or “Methandrostenolone”.
Thus, if the athlete is very responsible in choosing the dosage and administration of the drug, then growth hormone will be able to help achieve the necessary results and will not cause any side effects. But even if they occur, almost all of them are reversible. By the way, it’s worth adding to everything that scientists have discovered a certain rejuvenating effect of the hormone on the body (along with other positive effects).
Naturally, it is necessary to lead only a healthy lifestyle and eliminate all bad habits, and in the case of taking medications, it is best to consult a specialist or doctor.
Thus, now you have an idea of what hormone is responsible for growth, how exactly its synthesis occurs and how it can help achieve the goal. It is imperative to purchase drugs only in specialized institutions that have all the necessary documents and a license. Despite the fact that growth hormone that is spoiled or expired has virtually no negative effect on the body, there will be no benefit from such a product either, and the money will be wasted. By following simple rules regarding its purchase and use, you can easily and quickly achieve the desired results.
A small embryo born in the mother's womb grows very quickly. This is the work of a hormone whose purpose is the growth of the body. The hormone reaches its highest level in the fetus by 5-6 months of pregnancy. Incredibly, its concentration at this time is almost a hundred times greater than that of an adult. It is called somatotropin and is produced by a small gland - the pituitary gland (in the brain). There is a statement that a person grows mainly at night. Is it so?
Hormone secretion is a periodic phenomenon, with several peaks per day. The biggest surge in hormone production is observed at night, a couple of hours after falling asleep. That’s why there is an opinion that we grow at night. With its help, tubular bones begin to grow in length and protein production accelerates. The hormone is involved in metabolic processes and regulates the ratio of body weight to fat, promotes normal functioning of the brain and heart, causes an increase in the amount of glucose, being an insulin antagonist. It strengthens the bone structure and helps strengthen the muscle corset.
How the artificial compound became popular
With age, the amount of the hormone decreases, so a person becomes decrepit and ages: muscle mass is lost, bones become fragile, memory, sleep, speech, perception are impaired, endurance decreases, and fat accumulates. That’s why many people want to be in good physical shape in old age. The effect of an artificial anabolic drug on the human body has been studied and research was carried out back in the nineties of the last century. Renowned endocrinologist Daniel Rudman received positive results, albeit short-term.
But some people do not pay too much attention to the fact that growth hormone has quite serious side effects. Others simply ignore them, enjoying the positive effects of the administration of somatotropin and its analogues. Many prove that these drugs do not have a negative effect , if you don’t get carried away with them, but know when to stop.
The great desire to look great, have pumped up muscles like in celebrity photos, or lose weight has led to people not taking into account the side effects and believing that this cannot happen to them. Athletes, bodybuilders, movie stars and fashion models are ready to believe in any fairy tale for the sake of their beautiful image. They are told that synthetic growth hormones will improve the quality of life, they are promised that they will grow up, and a lot of magical properties are attributed to the injections:
- Increased strength and muscle tone.
- Reducing fat in problem areas.
- Restoring hair color, thickness and healthy appearance.
- Reducing the number of wrinkles, tightening the oval of the face.
- Improved vision.
- Normalization of blood pressure.
- Increased intimate powers.
- Clarification of consciousness, improvement of mental abilities, absence of depression.
Artificial growth hormone has many dangerous side effects and contraindications
Who will remain indifferent to such assurances? Being young and beautiful for a long time is very tempting. And they pay a lot of money for it, without even remembering that growth hormone has side effects and contraindications that are not at all safe.
Why is the drug dangerous?
A person who thinks about his image, which he has dreamed about so much, simply forgets that he needs to carefully adhere to the recommendations for use and not independently increase the duration of taking the medicine. For such brave souls, the results immediately make themselves known - side effects may appear:
- Swelling of the limbs, carpal tunnel syndrome (pain, numbness occurs due to enlarged muscles compressing the peripheral nerves).
- Muscles ache and symptoms of arthritis appear.
- Gigantism, increase in the volume of internal organs.
- Diabetes, a one-time increase in blood sugar levels - hyperglycemia.
- Hypertension.
- Hardening of the arteries.
- Headache.
Given these consequences, injections of the medication should be done by an experienced practitioner and very carefully. Endocrinologists around the world do not recommend using growth hormone for weight loss or rejuvenation.
Dr. Radman warned in his report that the effect of the drug is unknown in the distant future and the treatment is quite expensive, and similar results can be achieved through exercise. You just need to follow a certain course in accordance with your age.
The famous gerontologist Robert Neil Butler said about the introduction of somatotropin injections that there is a risk of cardiovascular diseases, cancer, and behavioral changes. However, we must admit that for some categories of people such treatment is simply necessary. These are children and adults whose natural growth hormone is particularly deficient. It is prescribed for spina bifida, genetic, chromosomal diseases, when patients are debilitated by serious illnesses.
A person may experience headaches when using the hormone.
A clear sign of an overdose is the appearance of pain. To prevent disproportionate growth of internal organs and bones, somatotropin should be taken strictly according to the instructions, increasing the dosage according to the scheme. Please note that the skeleton grows until the age of 28, so young men can only take growth hormones as a medicine on the recommendation of a doctor. Taking the hormone by young people in gyms to pump up muscles is unjustified; it is better to use stimulants for the reproduction of their own growth hormone. Do not forget that side effects, although infrequent, do occur.
Natural Methods to Increase Secretions
Anyone who truly cares about their health will not resort to injections. A person who understands that at his age growth hormone has begun to be produced less will try to change his lifestyle. You can achieve good results to increase hormone levels by following these methods:
- Proper nutrition. The diet should be balanced, which will help to form a beautiful body. Natural stimulators of growth hormone are amino acids, which are rich in pine nuts, eggs, pumpkin seeds and soybeans, cottage cheese and hard cheeses. Before going to bed, it is better to consume easily digestible proteins in the form of low-fat cottage cheese and chicken eggs.
- Healthy sleep. Remember that growth hormone is produced most during sleep? Sleep duration should be at least 8 hours. Daytime sleep, albeit short, is also useful. It will make you cheerful and energetic and increase the growth hormone.
- Physical exercise. Strength training every day for an hour will make your body unrecognizably beautiful and sculpted. This is the most effective method.
- Run. Run short distances and your muscles will quickly return to normal.
- Discharge. Do not accumulate fatigue and disappointment, stress and emotional distress. They need to be given a way out. A bath and a contrast shower, fasting days and communication with real friends help to come to your senses.
To stimulate the production of growth hormone, you need to eat right
All about somatotropin
Video: which growth hormone is better?
Video: what is growth hormone - positive and side effects
Rich Piana: Side effects of growth hormone
Growth hormone is called somatotropin, which causes a noticeable acceleration in the growth of young people (in length). This effect is observed only in the presence of growth zones in the bones, due to which the length of the tubular bones increases, including the upper and lower extremities. Initially, the drug was extracted from the pituitary gland of corpses, but later its synthetic analogue was obtained.
What is growth hormone and what is it for?
Somatotropin (abbr. STG, GR, HGH) is a peptide growth hormone produced in the anterior lobe of the pituitary gland (glands of the brain). In fitness, the substance is used to improve muscle relief. A natural deficiency of secretions in the human body leads to dwarfism. Normally, the concentration of somatotropin in an adult is from 1 to 5 ng/ml. Peak values of the substance in the blood can reach from 10 to 45 ng/ml.
Properties of somatotropin
Pharma is valued for:
- stimulation of muscle growth and inhibition of their destruction;
- reduction of subcutaneous fat;
- regulation of energy use;
- acceleration of healing and rejuvenation;
- stimulation of atrophied parts of the body;
- increase in height up to 26 years of age (due to bone tissue growth);
- increased blood sugar levels;
- stimulation of the immune system.
Some of these properties are achieved not directly, but through IGF-1 (insulin-like growth factor) produced in liver cells under the influence of somatropin. It is IGF-1 that stimulates the enlargement of internal organs and affects the course of processes in the body. Somatotropin enters the liver through the blood.
Secretion changes with age
The concentration and production of somatotropin are maximum in infancy, and peak values (maximum) are observed during adolescent puberty, as evidenced by increased linear growth (including the arms and legs). The secretion of the substance and the amplitude of the peaks decrease during growing up, and in old age they are minimal, which is associated with irreversible processes in the body.
Changes in secretion during the day
The release of the hormone into the circulatory system is inconsistent and changes intensity throughout the day. Peak emissions occur every three to five hours and depend on the biological characteristics of the body. The highest concentration is observed during night sleep, approximately an hour after going to bed. This is why quality sleep is so important when gaining muscle mass.
Growth hormone and bodybuilding
Somatotropin has gained significant popularity among athletes since its use in medicine. Athletes appreciated its properties of increasing muscles and reducing the amount of subcutaneous fat.
A few years after scientists obtained a recombinant substitute, growth hormone as a drug was included in the list of prohibited drugs by the Olympic Games Committee. Despite the ban, the hormone continues to be sold and has recently been gaining popularity, despite the high cost. It plays a special role in bodybuilding, where it is combined with similar anabolic steroids, however, its ineffectiveness has been proven in powerlifting.
Side effects
Like most medications, growth hormone has a negative effect on a number of body systems, in particular, the following are observed:
- hyperglycemia, increased blood pressure (circulatory system);
- tunnel syndrome (nervous system);
- fluid accumulation (excretory system);
- suppression of the thyroid gland.
Growth hormone stimulants
Somatostatin and somatoliberin are natural regulators secreted by cells of the hypothalamus (brain) into the venous system. They affect specifically somatotropes. Their balance and secretion are determined by a number of factors.
To stimulate the secretion of somatotropin, the use of hormonal drugs is not necessary. Without their participation, it is possible to increase the concentration of growth hormone in the blood up to three to five times.
The most effective stimulators of hormone production are peptides, which can increase the level of somatotropin up to 15 times, and their price is an order of magnitude lower than that of hormonal drugs.
The antihypertensive drugs moxonidine, as well as clonidine, are effective in stimulating the production of this hormone. The effect of doses of these drugs of 0.3 mg has been experimentally proven. The first of them increases the concentration of somatotropin in the blood by 27 times, and the second by 48. At the same time, moxonidine stimulates the production of insulin and reduces muscle destruction, which is important for antihypertensive therapy in bodybuilding.
The drug Baclofen (analogue of GABA) performs a similar function, has a euphoric and sedative effect, but penetrates the brain tissue better than GABA and is used as a muscle relaxant.
Works just as well:
Growth hormone course is a very expensive, effective and dangerous doping, although for medical purposes, under the supervision of doctors, somatotropin is practically harmless. Here it would be appropriate to recall the well-known Paracelsus, who somehow believed that everything is poison and everything is medicine. At the same time, they very often say that growth hormone is generally harmless, but they immediately recommend taking it together with insulin and/or thyroid hormones. A course of growth hormone, in fact, can lead to diabetes, suppress the secretion of thyroid hormones, and also contribute to the development of cancer. We definitely don’t recommend using co-ma-to-tro-pin, but, since there is no rest for the pumped-up, we’ll have to consider the reception and this- th drug.
A course of growth hormone involves injections of exogenous somatotropin, that is, we are not talking about the stimulation of its own secretion, but about the introduction of the hormone itself from the outside. There are several ways of producing co-ma-to-tro-pi-na, but we, like pot-re-bi-te-ley, are not in-te-re-su-et it’s how it’s produced, but how high-quality and cheap it is, or rather, what we’re interested in is the price-quality ratio, which we talk about in detail. -lee. The secretion of somatotropin can be stimulated with natural remedies and the use of peptides, but we will talk about this in separate articles. In this article, we will look at the best brands of growth hormone, how to check its quality, how to store it, how to take it, and what results other than cancer member, you can expect so-ma-to-tro-pi-na from the course.
Properties of somatotropin and consequences of taking
A growth hormone is a polypeptide hormone of the anterior pituitary gland, which in adolescence, until the “growth zones” of bones close, is responsible for their growth in length, which is what its name is associated with. Also, the functions of somatotropin include stimulating the synthesis of protein structures and the reduction of subcutaneous fat. This is why the growth hormone course alone is used only for “drying”, and together with AAS and/or in-su-lin also for gaining muscle mass. As you understand, in terms of protein metabolism, growth hormone and insulin are synergists, both hormones enhance protein synthesis, but in terms of carbohydrate metabolism they are antagonists. In-su-ling reduces the level of sugar in the blood, but growth hormone, on the contrary, significantly increases it. This is precisely why in long-term courses or when dosages exceed more than 10 units per day, so-ma-to-tropin is recommended together with insulin.
The natural production of growth hormone occurs according to circadian rhythms and, although the average value of the hormone in the blood is 1-5 ng/ml, during hormone releases this concentration can reach from 10 up to 40ng/ml. On average, such emissions occur every 3-5 hours and occur most intensely during sleep, and 1-2 hours after a person falls asleep, such a release necessarily occurs . Re-gu-li-ru-et-sya you work with somatoliberin and somatostatin, the first, as the name implies, sti- mu-li-ru-et the secretion of the hormone, and the second one slows it down. You raise this hormone with the hypothalamus, and all natural methods of increasing growth hormones and peptides act on the same principle - stimulate you-to-work-ku so-ma-to-li-be-ri-na gi-po-ta-la-mu-som.
Growth hormone can influence the synthesis of protein structures, both directly through co-ma-to-tropin receptors and through IGF-1. In general, the anabolic effects of so-ma-to-tro-pi-na are associated specifically with IGF-1, but the breakdown of fatty acids occurs along a different route. In practice, all of the above means 2 facts: a course of growth hormone can at the same time gain muscle mass and burn fat, but this can lead to serious consequences. -do with side effects. We have already listed them above, but it would not be amiss to say about them again: firstly, this is diabetes, but this side effect can be stopped with in-su-lin or diabetes-free CF, secondly , this is the suppression of the secretion of thyroid hormones, which is stopped by taking them during the course and, thirdly, the development of cancer cells, which is impossible to grow. It is also worth noting that insulin can lead to a hypo-gly-ke-mi-ches-koy with a fatal outcome, and thyroid hormones can -re-re-tion of own hormones.
During a course of somatotropin lasting up to 2 months and in dosages of up to 10 units per day, you can use Diabeton MB as a safer analogue of insulin. As for T3 and T4, that is, thyroid hormones, with dosages of up to 10 units per day and a course duration of up to 2-3 months, you can do without them. But we do not recommend that you live without androgenic anabolic steroids. In general, we don’t re-co-men-do-eat either one or the other, since amateurs don’t need it, and for pro-fessionals it’s simply not ethical, but, if you are so pumped up that you are injecting so-ma-to-tro-pin, then be so kind as to give yourself an AAS. The point here is simply a matter of effectiveness, taking co-ma-to-tro-pin without AAS is like drinking vodka without beer, you can, but there’s no point.
How to choose growth hormone
Today, the somatotropin market in Russia is flooded with growth hormones from Europe, China, as well as domestic manufacturers. European growth hormones are all very high quality, they can be bought at the pharmacy, as well as a number of Chinese and Russian preparations, but they are very expensive. Vadim Ivanov, owner of Do4a.com, conducted a number of pre-pa-ra-tov tests in 2015, checking their compliance with the declared quality, but we sis-te-ma-ti-zi-ro It was these data that produced the following table. But before moving on to its content, we would like to draw your attention to the fact that the % of pureness may vary depending on si-mos-ti depends on how long the growth hormone takes. It’s best to take the drug up to six months. The fact is that it needs to be stored at the op-re-de-lent temperature, and this is often violated, which leads to the destruction of the active substance . In terms of health, this is not scary, since somatotropin is dissolved in amino acids, but paying through the nose for protein is probably pointless.
| Name | Price for 10 units | A country | Certificate | Examination | Purity | Fake |
| Humatrope | 6000 rub. | France | There is | There is | 97-100% | There is |
| Saizen | 3700 rub. | Italy | There is | There is | 97-100% | There is |
| Rastan | 3425 rub. | Russia | There is | No | 94% | There is |
| Genotropin | 2300 rub. | Belgium | There is | There is | 94% | There is |
| Omnitron | 1750 rub. | Austria | There is | No | 93-95% | There is |
| Norditropin | 1650 rub. | Denmark | There is | No | 96% | There is |
| Jintropin | 1150 rub. | China | There is | There is | 95% | There is |
| Neotropin | 1000 rub. | China | No | No | 92% | few |
| Dynatrope | 800 rub. | Russia | No | No | 89% | No |
| Ansomon | 600 rub. | China | There is | There is | 97% | few |
| Hygetropin | 450 rub. | China | No | No | 93% | few |
The optimal drug, as the study showed, is ansomon, since all dealers without exception can imitate it. The fact is that in the Russian Federation there is no official pre-sta-vi-te-la, so anyone can order the drug directly from the factory. The quality and price of the ansomon have led to a frantic demand for this preparation, which is why it is always fresh, and the fresher the pot, the more active it contains substance, all things being equal. In general, at the time of writing the article, the optimal pre-pa-ra-t was ansomon, but what you inject yourself, people from the future, we still don’t know.
How to take a course of growth hormone
Storage of the drug: Growth hormone should be kept in the refrigerator, since high temperatures promote the destruction of somatotropin into amino acids.
Preparation of the drug: wipe the jar with somatotropin and the ampoules with the liquid with which you will dilute the drug with alcohol; the drug can be diluted with bactericidal or sterile water; the amount of liquid that you will dilute the growth hormone can be anything, it all depends on your preferences; if you dispense 10 units per 1 ml of liquid, then 10 marks on a U100 type syringe will equal 1 unit; the water drawn into the syringe must be mixed with growth hormone powder; for this, it is injected slowly through the syringe into the wall of the jar with so-ma-to-tro-pi-n, so that the water is honey-flax - but it flowed into powder, after which, with light circular movements, the mixture was reduced to a homogeneous mass in the form of a transparent liquid.
When and where to put: You need to take growth hormone in the morning before meals, 2 hours after meals and half an hour before meals, during or immediately after training, during drying, you can put it before bed if you wake up at night for in order to give an injection, then this will also be a good time for injections. In other words, injections should be given when your blood sugar is low. The drug must be administered at the same time. Growth hormones are placed under the skin, most often in the abdomen, which theoretically should contribute to a more rapid reduction of subcutaneous fat in this area. The injections are placed at an angle of 45° and are not given in the same place.
Duration and dosage: the duration of the course of growth hormone is from 2 to 6 months, and dosages range from 5 to 25 units per day; effective dosages start from 10 units, but they need to start from 2-3 weeks, provided that you feel normal; do-zi-rov-ki above 10 units per day are intended for pro-fes-sio-na-loving; The duration of the solo course is 2 months, if you use it for longer than 2 months, then you must include Diabeton MV, but long-term courses of 4-6 months are better because - be careful, because they may require the inclusion of insulin.
Solo course: intended for “drying”, the course begins with 5 units per day, injections are given once a day, if everything is fine, then at 2-3 weeks they begin to give 10 units per day, dividing them into two doses. ema. Duration is from 2 to 6 months, if the course lasts more than 2 months, then you need to drink Diabeton MV, if the course lasts more than 4 months, then you need to drink T-Rock-Sin 25 mcg per day for protection of the thyroid gland. Injections are not given for longer than 6 months, since this threatens to clog the receptors and the production of tolerance to the growth hormone.
Course with AAS: intended for “drying”, duration of AAS course is 8 weeks, give 30 mg win-stro-la per day, and the somatotropin course completely repeats the solo course.
Course with AAS and insulin: intended for weight gain, the duration of the AAS course is 8-12 weeks, as a rule, testosterone enanthate 500 mg per week, you can also add more oxandrolone 40 mg per day, the course of a small dose repeats the solo course, but in this case it is also not necessary to give 10 units of short-acting insulin per day, give 5 units an hour after the injection of somatotropin and after that eat tightly.
A course with AAS, insulin and thyroid hormones: this course can be for weight, it can be for cutting, it depends on whether insulin will be involved, but this course is simply long-term, that’s why During it, thyroid hormones are also given. Sometimes they charge 2 courses of AAS per cycle, and the dosage reaches up to 25 units per day, but this is a course for those who plan to take places in professional tournaments. So you just need to know that such courses simply exist in principle.
