In this article you can read the instructions for use of the drug Spregal. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Spregal in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Spregal analogues in the presence of existing structural analogues. Use for the treatment of scabies, demodicosis in adults, children, as well as during pregnancy and lactation.
Spregal- a combined drug for the treatment of scabies and demodicosis. Esdepalletrin, which is part of the drug, is a neurotoxic poison for insects. The mechanism of action is to disrupt the cation exchange of nerve cell membranes. Piperonyl butoxide enhances the effect of esdepalletrin.
Compound
Esdepalletrin (esbiol) + Piperonyl butoxide + excipients.
Pharmacokinetics
The components included in the drug are detected in the patient’s blood 1 hour after external use of Spregal. 24 hours after administration of the drug, the concentration of its components in the blood plasma is minimal, and in some cases not determined. 48 hours after using Spregal, no traces of its components are detected in the patient’s blood plasma.
Indications
- treatment of scabies, demodicosis.
Release forms
Aerosol for external use (sometimes mistakenly called spray).
There are no other dosage forms, be it cream, ointment or gel.
Instructions for use and method of use
It is preferable to start treatment in the evening (after 18-19 hours) so that the drug acts throughout the night. After applying the drug you should not wash. Before use, shake the container thoroughly. By spraying, the drug is carefully applied to the surface of the body (except for the skin of the face and head) at a distance of 20-30 cm from the surface of the skin. The drug is first applied to the torso, and then to the limbs (the treated areas begin to become shiny). The drug is applied especially carefully between the fingers, toes, in the armpits, perineum, on all folds and affected areas and left on the skin for 12 hours. After 12 hours, you must wash thoroughly with soap and dry.
As a rule, a single application of Spregal is sufficient. However, it must be borne in mind that even if the treatment is effective, itching and other symptoms may persist for another 8-10 days. If symptoms persist after this period, you can reapply the drug.
When treating children and newborns, while spraying the drug, it is necessary to cover their nose and mouth with a napkin; If diapers are changed, the entire buttock area must be re-treated. When scratches are localized on the face, they are treated with a cotton swab moistened with Spregal.
Side effect
- the appearance of a slight burning sensation, which usually passes quickly.
Contraindications
- bronchial asthma;
- obstructive bronchitis;
- lactation (breastfeeding);
- hypersensitivity to the components of the drug.
Use during pregnancy and breastfeeding
The use of the drug during pregnancy is possible only if the expected benefit to the mother outweighs the potential risk to the fetus.
If it is necessary to use the drug during lactation, you should stop breastfeeding for the period of treatment.
special instructions
The drug should be sprayed in a well-ventilated area.
One bottle of Spregal is enough to treat 3-4 people.
It is necessary to avoid getting the drug into the eyes and mucous membranes. In case of accidental contact with eyes, rinse them thoroughly with warm water.
To avoid secondary infection, bedding and clothing must be treated.
The drug is contraindicated in bronchial asthma, obstructive bronchitis only due to its aerosol form. In this case, it is possible to apply the drug to the skin with a cotton swab moistened with Spregal.
Drug interactions
There are no known drug interactions with Spregal.
Analogues of the drug Spregal
The drug Spregal has no structural analogues for the active substance. The drug is unique in its combination of active ingredients.
Analogs by pharmacological group (medicines for the treatment of scabies):
- Belogent;
- Benzyl benzoate;
- Sodium thiosulfate;
- Jurax.
If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.
The prevalence of this remedy for scabies is due to its low price and high therapeutic effect. A strong burning sensation in the area where the medicine is applied is the only drawback. You can buy benzyl benzoate at any pharmacy at an affordable price.
Benzyl benzoate is available in 2 dosages. A lower concentration is recommended for children.
Methods for treating scabies with benzyl benzoate:
- Take a shower before use to get rid of mites on the surface of the skin and improve blood supply to the epidermis;
- Spread the preparation evenly over the entire surface of the body. Exclude the face and head;
- After 2 days of application, a break of 3 days is recommended. Then it is treated for another 2 days;
- Disinfection of bed and clothing is carried out before the end of treatment.
Dermatologists consider benzyl benzoate emulsion to be a more effective remedy. Compared to ointment, a higher therapeutic effect is observed. The emulsion is well absorbed.
Rules for successful treatment of scabies
- Before starting treatment, you should change your underwear, bed linen, washcloths and take a shower.
- You cannot take a bath or shower during treatment.
- Any means - anti-scabies ointments, solutions, sprays are used at night, there is no need to treat the scalp under the hair, the whole body should be treated, not just the affected area.
- After treatment, you should also change your bed linen and underwear and take a shower.
- Previously, bedding and underwear should have been boiled for 5-10 minutes in washing powder or soda solution, but if you have an automatic washing machine, it is enough to select the longest program with the maximum temperature - this will be enough for disinfection. After this, to be sure, iron it on both sides.
- Pillows and blankets should be left outdoors for 5 days. The same applies to things that cannot be washed or toys, shoes - they should be sealed in plastic bags and waited for 5 days.
- Treat upholstered furniture and mattresses with an aerosol to kill insects.
- Topical treatments for scabies should not be used for longer than the doctor recommends, despite continued itching, as this may provoke itching from the drug and cause signs of overdose.
- If itching continues after treatment, continue taking antihistamines.
Solutions according to Demyanovich
This treatment method is named after the scientist who developed its recipe. The drug consists of two solutions: a 60% solution of sodium hyposulfite and hydrochloric acid at a 6% concentration. Both solutions are rubbed in separately, first sodium hyposulfite, then hydrochloric acid. The procedure should be carried out in a warm room, and upon completion it should be ventilated to get rid of foreign odors. The treatment procedure is carried out in the following order:
- sodium hyposulfite is slightly heated and thoroughly rubbed, starting with the hands and moving along the torso, the entire surface of the legs;
- rubbing time of the first solution is 15 minutes (about 3 minutes for each part of the body);
- 5-10 minute break to dry the skin;
- rubbing the second solution in the same sequence, but allotting a minute to each area (in this case, you need to make 4 passes with 5-minute breaks to dry the skin).
The next day the procedure must be repeated. After this, a person with scabies should not wash their skin for 3 days. This is not very pleasant, since after rubbing the composition there will be an unpleasant sensation and a persistent smell of sulfur, but this requirement must be observed.
Among the advantages of the method are low cost of treatment and high efficiency. Disadvantages include the difficulty of treating the skin and the manifestation of dermatitis if the technique is used incorrectly.
Course of the disease
Many patients are concerned about the question: how to cure scabies in one day? Almost nothing. But you can’t just start the disease. After a few weeks, the mild rash will develop into papulovesicular rash. The body thus reacts to the vital activity of ticks and exhibits an allergic reaction to their excrement. Some people even suffer from purulent rashes and bloody crusts, which are often symmetrical in nature.
Typical scabies is characterized by group itching. If all family members begin to itch more intensely in the evening, then a visit to the dermatologist should not be put off for long.
Instructions for use Spregal
Doctors advise starting treatment several hours before bedtime so that the effect of the drug is maximum. During the day, a person can wash off the medicine, accidentally remove it, and there will be no full treatment. After the aerosol has been applied to the skin, you cannot wash it. Typically, if several people live in the same apartment, they should all be treated with Spregal anti-scabies spray.
After treatment, the active components of the drug enter the bloodstream within an hour, but after a day the average concentration of the drug in the blood remains minimal. And after 48 hours, no trace of the medicine remains in the blood.
One can, which is intended for external use only, can treat 3 to 4 people.
There are rules for how to treat a person with Spregal, and if you follow the instructions, the treatment will bring tangible benefits after the first use.
Processing procedure
First, you need to choose the most optimal place for the procedure, since there should be no sources of fire nearby, and the room should not be too hot. The product ignites very quickly, which is why precautions are necessary. Smoking is strictly prohibited. You need to find a place that could be well ventilated after treatment with the spray, where there is access to fresh air.
There should be a base of non-slip material under the feet of the person being treated, as the medicine is oil-based and the floor may become slippery after treatment. Therefore, to avoid injury, you need to prepare a mat or towel in advance.
The procedure must begin with the torso, then the arms and legs are treated. You can't touch your head or face. The aerosol should be kept from the skin at a distance of 20-30 centimeters. Contact of the medicine with the eyes should be avoided. During spraying, you need to protect your eyes, nasal and oral cavities.
If the product penetrates the mucous membrane of the eyes, mouth or nose, rinse with a very large amount of water.
Getting the drug inside the body is very dangerous! If this happens due to negligence, immediately seek medical help so that gastric lavage is done within the first hour and symptomatic therapy with enterosorbents is prescribed.
Particular attention is paid to such areas on the skin as the places between the phalanges of the fingers and toes. Particular care must be taken to treat all flexural surfaces that scabies mites love to inhabit. The spray should also be applied thoroughly to the most affected areas. If traces of scabies are present on the face, in this case the inflamed surfaces are treated with a cotton swab dipped in Spregal spray. When during the procedure you feel unpleasant phenomena, the skin reacts with itching, severe tingling, you need to stop treatment and tell your doctor about this phenomenon.
The drug must remain on the skin for at least 12 hours. If you had to wash your hands at this time, you definitely need to apply Spregal again. After the treatment procedure, all clothes and underwear will need to be completely changed. Clothes worn before treatment must be urgently washed and treated so that a new infection does not occur.
After 12 hours, all remaining medication will need to be thoroughly washed off, washed with soap and wiped dry.
As practice shows, it is enough that the spray is used once, the effect is achieved immediately. Itching or other symptoms characteristic of scabies may continue for a week, but then they disappear without a trace. But if after treatment discomfort remains for a long time, the symptoms do not go away, then you should consult a doctor.
There is another important procedure - this is the treatment of linen and premises. Disinfection is a must. Furniture and carpeting in the house should be treated to remove any possible pockets of re-infestation.
If treatment is required for an infant, after changing the diaper or diapers, the buttocks are treated again.
A-Par
It is also an analogue of Spregal, the only difference is the volume of the bottle. A-Par is produced in the form of an aerosol in bottles of 152 g. The treatment regimen is similar to Spregal. First the body is processed, then the limbs. It is important to exclude the possibility of the spray getting into the eyes and other mucous membranes.
Before use, be sure to read the instructions with contraindications.
pharmachologic effect
The product contains a neurotoxic poison for insects, esdepalletrin, which damages their nervous system. The mechanism of action is associated with a disruption of cation exchange in the membranes of nerve cells. The substance piperonyl butoxide stimulates the effect esdepaletrina. The product begins to act after its first use.
Course and methods of treating scabies
The choice of treatment method is as important as the choice of medication, since the method determines how much of the anti-scabies agent will get under the patient’s skin. And in this case, the doctor makes his own choice, since treatment methods in this situation are not regulated in any way.
There are general rules that must be followed:
- Treat the entire body and limbs, not just the affected areas. Apply the product in a thin layer, especially carefully treat the hands, the skin between the fingers, armpits, scrotum and perineum.
- The dosage should not be large. You cannot use other drugs together with the main remedy.
- It is unacceptable for the medicine to come into contact with mucous membranes and eyes.
- If the disease is advanced and complications appear, skin lesions are treated first. Treatment of secondary infection is carried out with antiseptics and methods of general biotherapy. Eczema is treated with topical emollients.
- With Norwegian scabies, the patient is isolated and the affected skin is cleansed with keratolytic agents.
Helminths are often found in the bodies of children and adults. They are divided into 3 large groups:
- roundworms;
- flatworms (flukes);
- tapeworms.
Most anthelmintic drugs are available in tablet form. The most effective of them are Vermox, Praziquantel, Levamisole, Albendazole. "Levamisole" has the most powerful effect on round helminths (ascaris, toxocar, hookworm).The therapeutic effect is associated with the ability of the main active substance to cause paralysis of the smooth muscles of worms. The action begins a few hours after taking the tablets. After a day, the body is gradually freed from roundworms. It is important that Levamisole is able to stimulate the immune system, which is very important when treating patients. It can be used both for the treatment and prevention of helminthiasis.
It is indicated for the following helminthiases:
- ascariasis;
- toxocariasis;
- hookworm;
- strongyloidiasis;
- necatorosa.
"Albendazole" is prescribed for the following helminthiases: cysticercosis, echinococcosis, ascariasis, enterobiasis, trichuriasis, toxocariasis, necatoriasis, giardiasis, opisthorchiasis and some others. The drug cannot be used during the period of bearing and feeding a child, for diseases of the retina and individual intolerance. No less effective and in demand is a medicine called Praziquantel.
Vermox tablets
Vermoxa tablets can be used for prophylactic purposes. This is relevant if someone close to you has contact helminth infections (enterobiasis, hymenolepiasis). In such a situation, just a single dose of 1 tablet is enough. Vermox is well tolerated by children. When carrying out treatment, the doctor independently determines the dose for the child based on his age. The drug must be taken with water. A contraindication to the use of Vermox is the presence of ulcerative colitis or Crohn's disease.
The thing is that during treatment, a massive release of helminths (roundworms) from the intestines is possible, which can lead to intestinal obstruction. Contraindications are also age under 2 years, pregnancy and lactation, liver and kidney failure. It must be remembered that it is not advisable to prescribe Vermox simultaneously with Levamisole due to the possibility of intoxication of the body.
Drugs against protozoa
Antimalarials
Most often, representatives of the quinoline group are used to treat malaria. The most popular of them is Delagil. Recently, resistance to this drug has developed on the part of the causative agent of tropical malaria, so Delagil has begun to be used less frequently. This medication can also be used against amoebas. "Delagil" is taken as a preventive and therapeutic agent.
An alternative antimalarial drug is Quinidine. It is more toxic to the body, but has a stronger effect. Primaquine can be used to help patients with malaria. This is a synthetic aminoquinoline. When carrying out treatment using the above medications, the doctor must monitor blood counts and the patient’s condition.
Side effects
The drug has no significant side effects. A brief tingling or burning sensation may occur. In rare cases of individual intolerance to the components of the spray, allergic reactions occur. Be sure to follow the instructions, take precautions, do not take orally, avoid contact with mucous membranes.
Spregal spray price
Spregal analogues, synonyms and group drugs
Unknown.
Tablets are now very rarely used to treat scabies. Doctors prefer more modern medications. For example, Spregal spray. Products such as tablets are used only if ointments and sprays do not produce the desired effect.
The drug Butadione is considered effective. The active ingredient is phenylbutazone. It has a destructive effect against scabies mites. Release form: tablets. The use of this medicine produces an analgesic and anti-inflammatory effect. Take this way: 1 tablet 3 times a day.
Contraindications for use:
- children under 12 years of age;
- peptic ulcer;
- intolerance to acetylsalicylic acid;
- period of pregnancy and lactation;
- disorders of the cardiovascular system;
- renal failure;
- individual sensitivity to the components in the composition.
Medicines can only be used after a doctor's prescription.
Evgenia, 28 years old, Belgorod My husband works as a doctor. Due to the nature of his profession, he has to deal with a variety of people.
Most likely, he contracted demodicosis from one of his patients. His first symptoms began in early spring.
I think the tick had been living on his body for a long time, but as the weather conditions worsened, it became more active. At first, we attributed the red itchy pimples to allergies.
The husband nevertheless decided to turn to a colleague for help, who advised him to use Spregal. The treatment was carried out by the whole family.
The itching stopped almost immediately, the rash disappeared without a trace only after 10 days.
Svetlana, 32 years old, Irkutsk If you carry out high-quality disinfection in the house, carefully treat clothes and bedding, Spregal will really help get rid of the problem in one go. I, like many, attributed the small rashes on my son’s cheeks to allergies.
I was shocked when the dermatologist reported that some kind of mite lived on the child’s body. Initially, Spregal only helped for a short time.
A month later, the unpleasant symptoms returned. Then, on the recommendation of a dermatologist, she gave the house a thorough cleaning and boiled the child’s clothes and bedding.
I re-treated my son with the spray. The rashes went away and have not yet returned.
Masha, 25 years old, KurganSpregal is a really effective drug. The only thing I don't like is its pungent smell and stickiness immediately after application. Absorbs in 20-30 minutes. I was “lucky” to encounter both demodicosis and scabies. Both times I used Spregal. The unpleasant symptoms quickly went away.
Use of Spregal for pregnant women and newborns
The use of the drug for pregnant women is acceptable, but not advisable. For breastfeeding mothers, the drug is contraindicated! The final decision on the possibility of using the product should be made after consultation with a doctor.
The aerosol can be used by newborns. When handling, keep your eyes, mouth and nose safe. If the medicine gets on the baby's mucous membranes, they will need to be washed with plenty of warm water.
There is no evidence of negative effects in overdose. The spray does not affect the reaction and psychomotor functions, so you can drive a car or operate machinery during the treatment period.
There are certain conditions for storing Spregal spray. It should be kept in a safe place away from children. The temperature of this place should not exceed 25 degrees Celsius. It is strictly forbidden to heat the aluminum can over 50 degrees, pierce it, or try to open it. Avoid direct sunlight.
The period of use is two years.
You need to find out how much the product costs in pharmacies, the average price is 950 rubles.
Release form
The product is produced in the form of an aerosol for external use. This is a clear solution of light or dark yellow color. Contained in 152g continuous valved aluminum aerosol cans.
Indications
It is prescribed for the treatment of various types of scabies - typical, nodular, Norwegian, pseudo-scabies, scabies of “clean people”, swimmer’s itch, and sometimes for treatment of demodex skin mites. Before prescription, a test is carried out to determine the sensitivity of the pathogen to the drug. Developed in accordance with international safety standards, Spregal scabies aerosol is prescribed to infants and young children. In consultation with the doctor and strict adherence to the instructions, treatment of pregnant and lactating women is allowed.
Medifox
This medication for scabies is available in the form of a 5% cream and 24 ml bottles of solution. The cream should be rubbed over the entire surface of the body - from the soles of the feet to the head. Children also need to treat their forehead, temples and scalp. The approximate consumption of cream for one procedure is 30 g. The cream should remain on the skin for 14 hours, after which it can be washed off, and after 4 days the procedure can be repeated again.
A bottle of Medifox is designed for a three-day course of therapy. Before using the drug, it is necessary to prepare an aqueous emulsion consisting of 8 ml of medifox and 100 ml of boiled and cooled water. The finished emulsion is rubbed into the skin before going to bed so as to avoid getting it on the face, neck and hair. You can wash off the emulsion no earlier than 4 days of treatment. After taking a shower, you can replace your underwear and bedding and repeat the course.
Why is scabies sometimes difficult to cure?
Almost 80% of patients visit dermatological centers due to ineffective previously treated scabies. You should know that all substances used for therapy act on adult ticks without destroying the embryos, the development period of which is 4 days. Therefore, not a one-time treatment is necessary, but also repeated sanitation of the skin on the 4th day, which kills the larvae that hatched from the eggs.
Research states that among 195 patients, after a single treatment with permethrin cream, clinical recovery was observed in only 46% of patients. Therefore, none of the drugs used today in Russia should be used once.
Scabies is a disease that is not always easy to diagnose, as it sometimes complicates other skin diseases:
- Most often, the diagnosis is not difficult to establish, but there are atypical variants of scabies or its combination with other dermatological diseases.
- The main criterion confirming the diagnosis of scabies is the result of examination of scrapings from the lesion, as well as the clinical picture of the rash.
- In clean patients who wash their hands thoroughly and take a shower every day, rashes are usually scanty, the progression and spread of the disease is slow, and typical scabies are rare.
- In the summer-autumn period, a high incidence of scabies has recently been observed in Russia.
Symptoms and signs of the disease
The disease is accompanied by the following negative symptoms.
- Intense itching, worse at night.
- Formation of white stripes on the skin more than 15 mm long.
- Development of a characteristic rash on the skin.
- As a consequence of the active activity of the mite, the intensity of the itching increases every day.
- Very large scratches may form on the skin due to the inability to control oneself (especially during sleep).
- Lack of treatment causes purulent formations and the development of infection.
The disease may not manifest itself in any way during the first few days after infection. But as soon as the female lays the first eggs, the person will begin to feel itching, which will only intensify every day.
The disease can be detected at the initial stage only when the desire to itch arises. To treat the disease, special sprays are used.
What ointments relieve scabies?
The most effective form for treating scabies in a child is an ointment:
- Sulfuric acid is the most inexpensive drug. Method of application: daily rubbing into the skin affected by ticks for 7 days.
- “Permethrin” is a highly effective drug. You can completely get rid of the tick after 2 skin treatments.
- “Benzyl benzoate” is an ointment that can kill adult scabies mites in just 2 applications.
Important! The above drugs have different concentrations, so when purchasing an ointment, tell the pharmacist that you are buying it for a child.
Permethrin
After a single use, the patient receives protection from relapse for at least two weeks. Instructions for the drug are included in the package. You should definitely familiarize yourself with it.
Postscabiosis dermatitis
One of the consequences of the abuse of ointments and solutions in the treatment of the disease is postscabiosis dermatitis. Overdoses occur when, after completing therapy, the patient is still bothered by unpleasant sensations, for example, itchy skin. Some patients increase the dosage on their own, or start using other drugs, hoping to get a therapeutic effect. However, the itching only intensifies and an additional rash appears.
Postscabiosis dermatitis can manifest itself not only from excessive treatment, but also in patients with a tendency to allergic dermatosis, as well as in cases of individual resistance to drugs. This disease, unlike allergic contact dermatitis, affects only the skin of the body where there are the most intense abrasions of the skin. The rash is small in size, has no definite boundaries, cracks run through the skin, slight peeling and erosion are observed.
To get rid of post-scabiosis dermatitis, it is necessary to undergo a course of treatment with sedatives, calcium and antihistamines. In advanced cases, chatter or zinc paste is prescribed. In some situations, the doctor may recommend the use of hormonal creams (for example, sinaflan).
Sequential development of the disease
Experts distinguish the following stages of scabies:
Can be taken during pregnancy only if the expected benefit outweighs the possible risk. Spregal is not used during lactation.
What remedies for scabies are used in Russia?
Esdepalletrin
- A-Par aerosol 600 rub.,
- Spregal for scabies 900-1000 rub.
aerosol “Spregal” (France) Since this drug has no effect on tick eggs, body treatment is therefore indicated on days 1 and 5. Spregal is considered the most effective remedy for scabies and less toxic among all foreign drugs.
Spregal and A-par are easy to use, do not have an unpleasant odor, but can cause allergic reactions when inhaled, and part of the drug is absorbed into the blood through the skin.
Benzyl benzoate
- ointment 20% 30-40 rub.,
- emulsion 200g. 150 rub, 50g. 20 rub.
- lotion -20% 50ml. 140 rub.
Which ointment for scabies helps best? This is benzene benzoate. In pharmacies you can buy benzyl benzoate in the form of ointment, emulsion, lotion . This is a cheap and very effective remedy. An emulsion is more practical to use than an ointment. It is easy to wash, does not stain laundry, is easy to apply to the skin, the only minor drawback is that it does not have a strong specific smell.
Ointment, 10% benzyl benzoate, has a concentration insufficient for the treatment of adults, but is suitable for the treatment of children.Medifox
Medifox concentrate for the preparation of emulsion 5%. A modern remedy for scabies. Available in the form of a bottle containing 24 ml of the drug (for ease of use, labels are applied to the bottle). Apply externally in the form of a freshly prepared aqueous emulsion, for which 1/3 of the contents of the bottle is added to 100 ml of warm boiled water. The prepared emulsion is thoroughly rubbed into the skin of the body once a day (at night). The skin of the face and neck, as well as the scalp, cannot be treated. At the end of the course of treatment on the fourth day, the patient should take a shower and change his underwear and bed linen.Price: concentrate for preparing emulsion 100-120 rubles.
Simple sulfur ointment and Wilkinson's ointment
- Sulfur ointment for scabies 30-40 rub.
- Wilkinson 100 rub.
(composed of sulfur, naphthalan ointment, liquid tar, water, soap, calcium carbonate, manufactured by Permpharmacia. Time-tested sulfur-tar and sulfur ointments are also used against scabies, they are rubbed over the entire body for 5-7 days. Winkilson ointment Apply 1 time per day for 3 days.
A significant disadvantage of treating scabies with sulfur ointment, as well as with Wilkinson's ointment, is that they are unpleasant to the touch, are poorly absorbed, the skin takes on an unpleasant appearance, its use disrupts sweating, they have a strong unpleasant odor and stain linen.
Solutions according to Demyanovich
The prescription form is made to order, it is a 6% hydrochloric acid solution, 60% sodium hyposulfite solution.
Treatment with such a solution occurs in this way: first, 1 solution (60% sodium hyposulfite solution) is rubbed in, and then 2 solution (6% hydrochloric acid solution). Rubbing should be done in a warm room; after the procedure, it should be ventilated.How to process: 1 solution should be warmed up a little, rubbed thoroughly, starting with the hands, then the torso, legs, including the soles and toes, rubbing time is 3 minutes for each area, that is, it takes 15 minutes in total, then you need to take a short break for dry the skin and repeat the procedure.
After 10 minutes, rub in the 2nd solution, the processing sequence is maintained, each area takes 1 minute, so 3-4 rubbings should be done with 5 minute breaks for drying. The entire procedure is repeated the next day. Then the patient cannot wash for 3 days (neither bath nor shower can be taken). Only after 3 days you can swim. After treatment, the patient will not have a very pleasant sensation, and the solution has a sulfur smell.
Very often, dermatitis that occurs as a result of scabies appears in patients when they misuse drugs on their own initiative (in 82% of cases), or rather excessive and longer use than prescribed and recommended by the doctor. Persistent itching after treatment is the body’s reaction to the dead mite, and therefore does not require additional treatment.
pharmachologic effect
Combined drug for the treatment of scabies. Esdepalletrin, which is part of the drug, is a neurotoxic poison for insects. The mechanism of action is to disrupt the cation exchange of nerve cell membranes. Piperonyl butoxide enhances the effect of esdepalletrin.
Pharmacokinetics
The components included in the drug are detected in the patient’s blood 1 hour after external use of Spregal. Cmax of esdepalletrin is achieved 1 hour after administration of the drug; Cmax of piperonyl butoxide - 2 hours after application. 24 hours after administration of the drug, the concentration of its components in the blood plasma is minimal, and in some cases not determined. 48 hours after using Spregal, no traces of its components are detected in the patient’s blood plasma.
Indications
- treatment of scabies.
Dosage regimen
It is preferable to start treatment in the evening (after 18-19 hours) so that the drug acts throughout the night. After applying the drug you should not wash. Before use, shake the container thoroughly. By spraying, the drug is carefully applied to the surface of the body (except for the skin of the face and head) at a distance of 20-30 cm from the surface of the skin. The drug is first applied to the torso, and then to the limbs (the treated areas begin to become shiny). The drug is applied especially carefully between the fingers, toes, in the armpits, perineum, on all folds and affected areas and left on the skin for 12 hours. After 12 hours, you must wash thoroughly with soap and dry.
As a rule, a single application of Spregal is sufficient. However, it must be borne in mind that even if the treatment is effective, itching and other symptoms may persist for another 8-10 days. If symptoms persist after this period, you can reapply the drug.
During treatment children and newborns when spraying the drug, you must cover your nose and mouth with a napkin; If diapers are changed, the entire buttock area must be re-treated. When scratches are localized on the face, they are treated with a cotton swab moistened with Spregal.
Side effect
Local reactions: A slight burning sensation may occur, which usually passes quickly.Contraindications for use
- bronchial asthma;
- obstructive bronchitis;
- lactation (breastfeeding);
- hypersensitivity to the components of the drug.
WITH caution the drug is prescribed during pregnancy.
Use during pregnancy and breastfeeding
The use of the drug during pregnancy is possible only if the expected benefit to the mother outweighs the potential risk to the fetus.
If it is necessary to use the drug during lactation, you should stop breastfeeding for the period of treatment.
Use in children
Application is possible according to the dosage regimen.
Overdose
Currently, no cases of overdose of the drug Spregal have been reported.
Drug interactions
There are no known drug interactions with Spregal.
Conditions for dispensing from pharmacies
The drug is approved for use as a means of OTC.
Storage conditions and periods
The drug should be stored out of the reach of children at room temperature. Shelf life - 2 years.
The cylinder is under pressure: protect from sunlight and do not expose to temperatures exceeding 50°C. Do not pierce or burn even after use. Do not spray onto a fire source or hot object.
Use and store away from fire, heat sources and electrical appliances.
special instructions
The drug should be sprayed in a well-ventilated area.
One bottle of Spregal is enough to treat 3-4 people.
It is necessary to avoid getting the drug into the eyes and mucous membranes. In case of accidental contact with eyes, rinse them thoroughly with warm water.
To avoid secondary infection, bedding and clothing must be treated.
The drug is contraindicated in bronchial asthma, obstructive bronchitis only due to its aerosol form. In this case, it is possible to apply the drug to the skin with a cotton swab moistened with Spregal.
Anti-inflammatory bactericidal, insecticidal drug.
Price from 725 rub.
Anti-inflammatory bactericidal, insecticidal drug.
Application- scabies, demodicosis.
Analogs- Permethrin ointment, Scabicar, Benzyl benzoate ointment. You can find out more about analogues, their prices, and whether they are substitutes at the end of this article.
Today we’ll talk about Spregal aerosol. What is this product and how does it affect the body? What are the indications and contraindications? How and in what doses is it used? What can be replaced?
What kind of remedy
Available in the form of a spray for external use.
The aerosol is produced by Laboratoires OMEGA PHARMA FRANCE (France), 152 g of the drug in an aluminum canister in a cardboard package. Sold in pharmacies without a prescription.
Active ingredient and composition
The active ingredients are Esdepallethrine and Piperonyl butoxide.
The auxiliary composition of Spregal contains the following components:
- ethanol 96%;
- macroglycerides;
- diethylene glycol monoethyl ether;
- propellant HFA 134a.
Pharmacological properties
The action begins after the first application.
Pharmacodynamics and pharmacokinetics
The maximum concentration of the active substance in the blood reaches an hour after use.
The drug is completely eliminated from the body after 48 hours.
Indications for use
Spregal instructions for use say that the indications for use of the drug are scabies and the facial area.
Contraindications
Due to its aerosol form, the drug is contraindicated in chronic respiratory tract pathologies, such as obstructive bronchitis and asthma.
The drug is also contraindicated for:
- hypersensitivity to the components included in the composition;
- lactation.
Directions for use and dosage
Treatment for scabies is carried out in the evening on clean, dry skin of the body. The drug is sprayed from a distance of 20 cm until lightly moistened, avoiding contact with the face. When processing in infancy, the child's face is covered with a napkin or cloth. At each diaper change, repeat applying the product to the buttocks and inguinal folds.
The interdigital areas, skin folds, and armpits are treated with special care. To prevent the spread of the disease, experts recommend treating the whole family for preventive purposes. One bottle of Spregal aerosol is enough to treat 4 people.
When treating demodicosis of the face, the product is applied to the affected area with a tampon.
Spregal should remain on the skin for half a day.
The course of treatment is designed for one or two applications. Symptoms in the form of itching can persist for up to 8 days. If after the specified time the symptoms persist, the treatment should be repeated.
In childhood, during pregnancy and breastfeeding
Use in childhood is possible according to Spregal instructions for use. Use with caution during pregnancy. The drug is contraindicated during breastfeeding.
Side effects
Local skin reactions may occur in the form of burning and redness of the skin.
special instructions
Use the product only in a ventilated area.
Avoid contact with mucous membranes. In case of contact, rinse thoroughly with water.
To avoid re-infection, the patient’s clothing and bedding are also treated with Spregal.
Overdose
With topical use of the drug Spregal spray for scabies, no cases of overdose have been identified.
Drug interactions
No mechanisms of mutual influence of Spregal aerosol on other topical medicinal products were found.
Analogs
Spregal analogues of the drug based on the main active ingredient is drug A - Par.
According to therapeutic effect:
- Benzyl benzoate ointment;
- Sulfuric ointment;
- Permethrin ointment;
- Scabicar;
- Medifox.
The use of the drug and analogues without consulting a doctor is unacceptable and can lead to undesirable consequences.
5 minutes to read. Published 11/09/2018
In this article:
Description and pharmacological action
Spregal spray contains two main potent substances - esbiol and piperonyl butoxide. Additional components include ethanol, macroglyceryls, and propellant. The solution is completely transparent and has a light yellow tint. Thanks to the convenient packaging, the medicine is convenient to spray and apply evenly to the skin.
The pharmacological effect of the drug is associated with the presence of components that have a general insecticidal effect. Esbiol is a neurotoxic poison that has a negative effect on insects and contributes to their destruction.
After contact of pests with the drug, cation exchange in the membranes of nerve cells is disrupted. Piperonyl butoxide enhances the effect of esbiol.
This video describes methods to combat scabies:
Mode of application
The instructions for use of Spregal describe in detail the recommendations from the manufacturer. The drug must be applied evenly to the surface of the body. Do not spray the spray on your face or scalp. The optimal distance is 20−30 centimeters. First, the product is applied to the body, then the arms and legs are treated.
Spregal spray should be applied first to the torso, and only then to the arms and legs. To remove the product from your body, you need to shower with soap. In most cases, a single use of the spray is sufficient for patients. Sometimes after application, symptoms of scabies persist for 7 days. If clinical manifestations have not disappeared after a week, body needs to be re-processed and also consult your doctor.
In order to remove the product from the body, you need to take a shower with soap. The drug Spregal is allowed to treat small and newborn children. When spraying the product, be sure to cover your mouth and nose with a napkin.
After each diaper change, the buttock area is re-treated. To eliminate scratching on the face, apply the product to the affected areas applied with a cotton swab.
Contraindications to treatment
Before starting treatment, it is important to familiarize yourself with all contraindications so as not to harm the body.
The manufacturer indicates several main diseases, for which it is prohibited to use Spregal spray:
- bronchial asthma;
If you have bronchial asthma, taking Spregal spray is contraindicated - obstructive bronchitis;
- individual hypersensitivity to individual components.
All these contraindications apply to the drug, which is available in spray form. For bronchial asthma and bronchitis, to treat the body, you can take a swab, moisten it in the product and apply it to the skin.
Inexpensive analogues
There are several effective inexpensive analogues that perfectly replace Spregal spray. Before starting therapy, it is recommended to consult with your doctor.
The following substitutes can be distinguished:
These two drugs have their own contraindications. They should not be applied to the skin of children under one year of age. The main contraindication is individual intolerance to individual components of the drug.
Another effective substitute that is inexpensive is Permethrin. The cost of this product is only 150 rubles. Permethrin is completely similar in its composition, indications and method of use to Spregal spray.
Permethrin is a cheap analogue of Spregal spray Another analogue substitute for Spregal is A-Par spray. It is produced in France, its structure is similar to a spray. Recently, the drug Para-Plus appeared in pharmacies. It is used exclusively for external use.
Spray A-Par is a good analogue of Spregal spray Spregal has proven itself well for the treatment of scabies, so it is often recommended for use against subcutaneous mites. To choose a cheaper analogue, you need seek help from your doctor. He will definitely study the indications and possible contraindications for use, as well as the advisability of replacing medications. The price of Spregal analogs is several times lower, but many of them have a similar composition and mechanism of action.
