This page provides a list of all analogues of Buserelin-Long by composition and indication for use. A list of cheap analogues, and you can also compare prices in pharmacies.
- The cheapest analogue of Buserelin-Long:
- The most popular analogue of Buserelin-Long:
- ATX classification: Buserelin
- Active ingredients/composition: buserelin
Cheap analogues of Buserelin-Long
| # | Name | Price in Russia | Price in Ukraine |
|---|---|---|---|
| 1 | triptorelin | 1919 RUR | 134 UAH |
| 2 | triptorelin Similar in indication and method of use | 2617 RUR | 893 UAH |
| 3 | goserelin Similar in indication and method of use | 3200 rub. | 750 UAH |
| 4 | buserelin acetate Analogue in composition and indication | 3285 RUR | 1850 UAH |
| 5 | triptorelin acetate Similar in indication and method of use | 5420 rub. | -- |
When calculating the cost cheap analogues of Buserelin-Long the minimum price was taken into account, which was found in the price lists provided by pharmacies
Popular analogues of Buserelin-Long
The list of drug analogues based on statistics of the most requested drugs
All analogues of Buserelin-Long
The above list of drug analogues, which indicates substitutes Buserelin-Long, is the most suitable because they have the same composition of active ingredients and coincide in indications for use
Analogues by indication and method of use
| Name | Price in Russia | Price in Ukraine |
|---|---|---|
| leuprorelin | -- | -- |
| leuprorelin | -- | -- |
| RUB 16,753 | 2437 UAH | |
| leuprorelin | RUB 16,753 | 2437 UAH |
| leuprorelin | -- | -- |
| leuprorelin | 7875 RUR | 1926 UAH |
| goserelin | 3200 rub. | 750 UAH |
| triptorelin | 2617 RUR | 893 UAH |
| triptorelin | 8076 RUR | 1915 UAH |
| triptorelin | 1919 RUR | 134 UAH |
| triptorelin acetate | 5420 rub. | -- |
To compile a list of cheap analogues of expensive drugs, we use prices that are provided to us by more than 10,000 pharmacies throughout Russia. The database of drugs and their analogues is updated daily, so the information provided on our website is always up to date as of the current day. If you have not found the analogue you are interested in, please use the search above and select the medicine you are interested in from the list. On the page of each of them you will find all possible analogues of the drug you are looking for, as well as prices and addresses of pharmacies where it is available.
How to find a cheap analogue of an expensive medicine?
To find an inexpensive analogue of a medicine, a generic or a synonym, first of all we recommend paying attention to the composition, namely the same active ingredients and indications for use. The same active ingredients of a drug will indicate that the drug is a synonym for the drug, pharmaceutically equivalent or a pharmaceutical alternative. However, we should not forget about the inactive components of similar drugs, which may affect safety and effectiveness. Do not forget about the instructions of doctors; self-medication can harm your health, so always consult a doctor before using any medication.Buserelin-Long price
On the websites below you can find prices for Buserelin-Long and find out about availability at a pharmacy near youBuserelin-Long instructions
INSTRUCTIONS
on the use of the drug
Buserelin-long
Compound
Lyophilisate for the preparation of a suspension for intramuscular administration of prolonged action, containing 3.75 mg of buserelin.
pharmachologic effect
Pharmacotherapeutic group:
antitumor agent, gonadotropin-releasing hormone (GnRH) analogue.
Buserelin-long, indications for use
Hormone-dependent prostate cancer;
Mammary cancer;
Endometriosis (pre- and postoperative periods);
Uterine fibroids;
Hyperplastic processes of the endometrium;
Treatment of infertility (during an in vitro fertilization (IVF) program).
Contraindications
Pregnancy;
Lactation period;
Hypersensitivity to the components of the drug
Directions for use and doses
For hormone-dependent prostate cancer, Buserelin-long is administered at a dose of 3.75 mg (1 injection) intramuscularly (IM) every 4 weeks. In the treatment of endometriosis and endometrial hyperplastic processes, the drug is administered in a dose of 3.75 mg intramuscularly once every 4 weeks. Treatment should begin in the first five days of the menstrual cycle. Duration of treatment is 4 - 6 months. When treating uterine fibroids, Buserelin-long is administered at a dose of 3.75 mg intramuscularly once every 4 weeks. Treatment should begin in the first five days of the menstrual cycle. Duration of treatment - 3 months before surgery, in other cases - 6 months; 2 When treating infertility using in vitro fertilization (IVF), Buserelin-long is administered in a dose of 3.75 mg (1 injection) intramuscularly once at the beginning of the follicular phase (on the 2nd day of the menstrual cycle) or in the middle of the luteal phase (21 - 24 days ) menstrual cycle preceding stimulation. After blockade of pituitary function, confirmed by a decrease in the concentration of estrogen in the blood serum by at least 50% of the initial level (usually determined 12 to 15 days after injection of Buserelin-long), in the absence of ovarian cysts (according to ultrasound), the thickness of the endometrium is not more than 5 mm, stimulation of superovulation begins with gonadotropic hormones under ultrasound monitoring and control of the level of estradiol in the blood serum.
Side effects
Allergic reactions: urticaria, skin hyperemia, rarely - angioedema.
From the central nervous system: frequent mood swings, sleep disturbances, depression, headache.
From the musculoskeletal system: with long-term use - bone demineralization, which is a risk of developing osteoporosis.
In women - headache, depression, sweating and changes in libido, dryness of the vaginal mucosa, pain in the lower abdomen, rarely - menstrual bleeding (during the first weeks of treatment).
In men, during the treatment of prostate cancer - during the first 2 - 3 weeks after the first injection, buserelin can cause exacerbation and progression of the underlying disease (associated with stimulation of the synthesis of gonadotropins and, accordingly, testosterone), gynecomastia, possible “hot flashes”, increased sweating and decreased potency (rarely requires discontinuation of therapy), transient increase in the concentration of androgens in the blood, urinary retention, “renal edema” - swelling of the face, eyelids, legs; muscle weakness in the lower extremities. When patients with prostate cancer begin treatment, they may experience a temporary increase in bone pain; in this case, symptomatic therapy should be carried out. Isolated cases of ureteral obstruction and spinal cord compression have been noted.
Other: in isolated cases (the cause-and-effect relationship has not been clearly established) - pulmonary embolism, dyspeptic disorders.
special instructions
In women, patients with any form of depression should be under close medical supervision during treatment with the drug. Ovulation induction should be performed under strict medical supervision. In the initial stage of treatment with the drug, the development of ovarian cysts is possible. 5 Before starting treatment, it is recommended to exclude pregnancy and stop taking hormonal contraceptives, however, during the first two months of using the drug, it is necessary to use other (non-hormonal) methods of contraception. After cessation of treatment, ovarian function is restored. The first menstruation resumes after 3 months. In men In order to effectively prevent possible side effects in the first phase of the drug's action, it is necessary to use antiandrogens two weeks before the first injection of Buserelin-long and for two weeks after the first injection.
INFLUENCE ON THE ABILITY TO DRIVE A CAR AND OTHER MECHANISMS
Caution should be exercised when prescribing the drug to patients engaged in potentially hazardous activities that require increased attention and speed of mental and motor reactions.
Drug interactions
The simultaneous use of the drug "Buserelin-long" with drugs containing sex hormones (for example, in the mode of ovulation induction) may contribute to the occurrence of ovarian hyperstimulation syndrome. With simultaneous use, Buserelin-long may reduce the effectiveness of hypoglycemic agents.
Overdose
Currently, no cases of overdose have been reported.
Storage conditions
In a dry place, protected from light, at a temperature not exceeding 25°C.
Keep out of the reach of children.
Latin name: Buserelin Long
ATX code: L02AE01
Active substance: Buserelin
Manufacturer: F-Sintez, Russia
Conditions for dispensing from a pharmacy: On prescription
Buserelin Long is classified as an antitumor drug and is a synthetic analogue of the gonadotropin-releasing hormone.
Indications for use
The use of drugs is indicated for the treatment of hormonal dysfunctions that are caused by hyperestrogenism (both absolute and relative):
- Endometriosis (therapeutic therapy before and after surgery)
- Hyperplastic changes in the endometrial layer of the uterus
- The presence of myomatous nodes.
Buserelin can be prescribed for the purpose of in vitro fertilization (IVF) during infertility treatment.
Compound
The lyophilisate contained in the ampoules contains Buserelin Long - 3.75 mg. Additional components include the following substances:
- Dl-lactic and glycolic acid – 200 mg
- D-mannitol – 85 mg
- Sodium carmellose – 30 mg
- Polysorbate – 2 mg.
To dissolve the lyophilisate, mannitol (0.8% solution) in 1 ml of purified water is used.
Medicinal properties
Buserelin Long FS is a highly effective antitumor drug, similar to natural GRF. The effect of buserelin on the body is based on temporary stimulation of the growth of sex hormones in the blood; it is due to this that a competitive connection occurs with specific receptors of cells located on the surface of the anterior pituitary gland.
If the drug is used exclusively in therapeutic dosages, a blockage of gonadotropic pituitary activity is observed (usually after 12-14 days). On buserelin, the production of testosterone, LH and FSH is reduced, which subsequently contributes to the inhibition of the synthesis of sex hormones inside the gonads. In this case, In women, the level of estradiol is equal to the postmenopausal level; in men, the average value of testosterone decreases to the level characteristic of the post-castration period.
During continuous use of the drug Buserelin Long FS for 2-3 weeks. the testosterone level decreases significantly, thereby achieving the state of orchiectomy (so-called pharmacological castration is observed).
After injection into the muscle, the bioavailability of the drug is quite high.
The highest concentration of the active substance of the drug is observed 2-3 hours after the injection (dose - 3.75 mg), and subsequently remains at the level necessary to inhibit the production of gonadotropins by the pituitary gland (at least 4 weeks).
Release form
Price from 3400 to 4400 rubles.
Buserelin Long FS in the form of a lyophilisate is available in 10 ml dark glass bottles; an additional solvent (2 ml) is included in neutral glass ampoules with instructions. Inside the cell packaging there are:
- bottle of Buserelin Longa
- solvent ampoule
- syringe for single use (5 ml)
- scarifier
- 2 napkins soaked in alcohol.
Buserelin Long: instructions for use
The drug Buserelin Long should be administered intramuscularly only. There is no significant difference at what time of day the injection is given.
The preparation of a medicinal suspension with buserelin is carried out before its administration using the supplied solvent.
A healthcare worker should prepare the solution and inject the drug.
Treatment with this drug is prescribed depending on the type of disease:
- Oncological processes in the prostate (hormone dependent) – 1 in. into the muscle (3.75 mg) with a time interval of 4 weeks.
- Hyperplastic changes in the endometrial layer and endometriosis - therapeutic therapy begins on the 5th day of MC in a single dosage of 3.75 mg, the medication is administered every 4 weeks, the course of therapy is 4-6 months.
- Uterine fibroids - a one-time injection into the muscle with a dosage of 3.75 mg; the drug must be re-injected after 4 weeks. Treatment should be started within 5 days. from the day of the onset of MC, before surgery, therapy is carried out for 3 months, in other cases – 6 months. (in combination with different drugs).
- Infertility treatment – introduction 1 in. into the muscle for 2 days. MC (the possibility of an injection on 21-24 days of MC is not excluded) before the hyperstimulation procedure. After the estrogen level decreases by 2 times, gonadotropic hormones are prescribed. Therapeutic therapy for infertility with other drugs is carried out in the absence of cystic changes in the ovaries and with regular monitoring of estradiol levels and ultrasound.
Use during pregnancy and pregnancy
Not prescribed for this group of patients.
Contraindications
- Increased sensitivity to buserelin
- Pregnancy, GW.
Precautionary measures
To prevent the development of adverse reactions in men in the first phase of the drug’s action, it is recommended to combine the use of this drug with androgenic drugs (2 weeks before the administration of buserelin and 2 weeks after the injection).
If there are signs of depression during antitumor therapy, it is best to provide the patient with constant medical supervision.
To achieve good results in the treatment of infertility (IVF procedure), it is necessary to control the induction of ovulation while using buserilin.
Usually the drug from a domestic manufacturer is well tolerated, but in some cases the growth of ovarian cysts can be diagnosed.
Before therapy, it is necessary to exclude pregnancy and replace the COCs taken with a drug that has a different hormone content (the first 2 months of treatment).
After complete withdrawal of the drug Buserelin Long FS, restoration of ovarian function is observed (after 3 months), no differences in their activity compared to the period before treatment are observed.
Particular care must be taken when driving a vehicle and when working with precision machinery.
It is not recommended to purchase the drug outside the pharmacy chain, paying attention to the advertisements “I am selling or selling Buserelin Long at a low price.” The difference between medications purchased in a pharmacy chain and “from hand” can be significant, because the purchase of a counterfeit cannot be ruled out.
Cross-drug interactions
It is worth paying attention to the interaction of buserelin with other drugs that contain different sex hormones. It cannot be said that they are incompatible with the drug Buserelin Long FS, but against the background of complex use, ovarian hyperstimulation syndrome may develop.
The drug can reduce the therapeutic effect of the use of hypoglycemic drugs.
If we talk about compatibility with other drugs, then at the moment there is no reliable information.
Alcohol compatibility
Buserelin and alcohol cannot be combined. During treatment, you must completely stop drinking alcohol. There is a negative effect of alcohol on the functioning of the reproductive system. Under the influence of alcohol, metabolic processes are disrupted and the synthesis of sex hormones slows down.
Side effects
Although the drug has good healing properties, side effects may occur during therapy.
For men:
- Exacerbation of the course of oncological processes in the prostate
- Gynecomastia
- Deterioration of erection
- Severe rush of blood to the head
- Excessive sweating
- Increase in androgen levels in the blood
- Swelling of the limbs and face
- Muscle weakness
- Difficulty passing urine
- Development of ureteral obstruction, rarely – disruption of the spinal cord.
Among women:
- Breakthrough bleeding according to the type of menstruation
- Development of depression
- Severe headaches
- Impaired sleep quality
- Change in emotional mood
- Feeling of dryness inside the vagina
- Feeling of "hot flashes"
- Painful sensations in the lower abdomen
- Increased sweating
- Decline in libido.
General symptoms may also occur:
- Hyperemia of the skin
- Urticaria-type rash
- Demineralization of bone tissue
- Rarely - the development of dyspeptic symptoms, the development of thromboembolism of one of the arteries of the lungs.
Storage conditions and shelf life
The antitumor drug Buserelin Long FS should be stored at a temperature not exceeding 25 C. The shelf life is 2 years.
Analogs
Pharmsintez, Russia
Price from 3624 to 4611 rub.
Buserelin Depot is an excellent drug with antitumor properties; the active ingredient is buserelin. Prescribed for the treatment of cancer of the genitourinary system in men and women, and is used in the treatment of infertility. Produced in the form of a lyophilisate.
Pros:
- Has good antiandrogenic properties
- Used to treat endometriosis
- Highly effective in the treatment of malignant neoplasms of the mammary gland.
Minuses:
- Expensive
- Dispensed according to prescriptions
- High risk of adverse reactions.
pharmachologic effect
A synthetic analogue of natural GnRH. Competitively binds to the receptors of the cells of the anterior pituitary gland, causing a short-term increase in the level of sex hormones in the blood plasma.
The use of the drug in therapeutic doses leads (on average after 12-14 days) to a complete blockade of the gonadotropic function of the pituitary gland, thus inhibiting the release of LH and FSH. As a result, there is a suppression of the synthesis of sex hormones in the ovaries and a decrease in the concentration of estradiol (E2) in the blood plasma to postmenopausal values.
Pharmacokinetics
When administered intranasally, the drug is completely absorbed through the nasal mucosa.
Excreted in small quantities into breast milk.
T 1/2 is about 3 hours.
Indications
Hormone-dependent pathology of the reproductive system caused by absolute or relative hyperestrogenism:
— endometriosis (pre- and postoperative periods);
- uterine fibroids;
— hyperplastic processes of the endometrium;
— treatment of infertility (during an in vitro fertilization program).
Dosage regimen
At treatment of endometriosis, uterine fibroids, endometrial hyperplastic processes the drug is administered into the nasal passages after cleansing them at a dose of 900 mcg/day. A single dose of the drug when the pump is fully pressed is 150 mcg. The daily dose of the drug is administered in equal portions, one injection into each nostril 3 times a day at regular intervals (6-8 hours) in the morning, afternoon and evening. Treatment with Buserelin should begin on the first or second day of the menstrual cycle and be administered continuously throughout the entire course of treatment. The course of treatment is 4-6 months.
At infertility treatment using in vitro fertilization method the drug is administered intranasally, one injection (150 mcg) into each nostril 3-4 times a day at regular intervals. Daily dose 900-1200 mcg. Buserelin is prescribed at the beginning of the follicular phase (on the 2nd day of the menstrual cycle) or in the middle of the luteal phase (21-24 days) of the menstrual cycle preceding stimulation. After 14-17 days, when estradiol in the patients’ blood serum decreases by at least 50% of the initial level, there are no cysts in the ovaries, and the thickness of the endometrium is no more than 5 mm, stimulation of superovulation with gonadotropic hormones begins under ultrasound monitoring and control of the level of estradiol in the blood serum. If necessary, the dose of Buserelin can be adjusted.
Side effect
From the side of the central nervous system: headache, dizziness, nervousness, fatigue, sleep disturbance, drowsiness, decreased memory and ability to concentrate, emotional lability, development of depression or worsening of its course.
From the senses: tinnitus, hearing and vision impairment (blurred vision), feeling of pressure on the eyeball.
From the endocrine system:"flushes" of blood to the skin of the face and upper chest, increased sweating, vaginal dryness, decreased libido, pain in the lower abdomen, bone demineralization; rarely - menstrual-like bleeding (usually during the first weeks of treatment).
From the cardiovascular system: palpitations, increased blood pressure (in patients with arterial hypertension).
Allergic reactions: urticaria, skin itching, skin hyperemia, very rarely - bronchospasm, anaphylactic and/or anaphylactoid shock, angioedema.
From the digestive system: nausea, vomiting, thirst, diarrhea, constipation, loss of appetite, weight gain or loss.
From the laboratory parameters: decreased glucose tolerance, hyperglycemia; changes in the lipid spectrum; increased activity of serum transaminases, hyperbilirubinemia; thrombocytopenia or leukopenia.
Others: in isolated cases - nosebleeds; pulmonary embolism; swelling in the ankles and feet; weakening or increasing hair growth on the head and body; pain in the back, joints.
Local reactions: irritation of the nasal mucosa, dryness and pain in the nose.
Contraindications for use
- pregnancy;
- lactation period;
- hypersensitivity to the components of the drug.
WITH caution The drug should be used for arterial hypertension, diabetes mellitus, and depression.
Use during pregnancy and breastfeeding
The use of the drug during pregnancy and lactation is contraindicated.
Overdose
Currently, no cases of overdose of Buserelin have been reported.
Drug interactions
The simultaneous use of Buserelin with other drugs containing sex hormones (for example, in ovulation induction mode) may contribute to the occurrence of ovarian hyperstimulation syndrome.
With simultaneous use, Buserelin may reduce the effectiveness of hypoglycemic agents.
Conditions for dispensing from pharmacies
The drug is available with a prescription.
Storage conditions and periods
List B. The drug should be stored out of the reach of children, protected from light at a temperature of 8° to 25°C. Shelf life - 3 years.
special instructions
Patients with any form of depression during treatment with Buserelin should be under close medical supervision.
Ovulation induction should be performed under strict medical supervision.
In the initial stage of treatment with the drug, the development of ovarian cysts is possible.
A repeated course of treatment should be started only after a careful assessment of the balance between the expected benefit and the potential risk of developing osteoporosis.
Patients who wear contact lenses may experience signs of eye irritation.
Given the intranasal route of administration, irritation of the nasal mucosa is possible, and sometimes nosebleeds. The drug can be used for rhinitis, but before using it, the nasal passages should be cleaned.
The use of the drug Buserelin in combination with surgical treatment for endometriosis reduces the size of pathological foci and their blood supply, inflammatory manifestations and, therefore, reduces the operation time, and postoperative therapy improves results, reducing the frequency of postoperative relapses and reducing the formation of adhesions.
Impact on the ability to drive vehicles and operate machinery
During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Buserelin is used for the complex treatment of hormone-dependent malignant tumors in men and women. This product is available in the form of a nasal spray or solution for intramuscular injection. In the pharmacy, the medicine may be called: “Buserelin-depot”, “Buserelin-long” or simply “Buserelin”. This synthetic analogue of natural gonadotropin-releasing hormone is especially helpful in the treatment of endometriosis (the main complication of which is infertility).
The combination of a course of conservative treatment with Buserelin with surgery for endometriosis significantly reduces blood loss during surgery and its duration. During the recovery period, the use of these hormones suppresses the development of remaining foci of inflammation, improves the processes of tissue repair and regeneration.
Pregnancy after Buserelin depot or long can occur in 2-4 months. In addition to endometriosis, Buserelin is used in the treatment of prostate cancer in men, breast cancer in women, and uterine fibroids.
Comparison of types of drugs produced
Buserelin Long and Depot - the difference can be seen in the comparative table. And only the attending physician can say which form is best to choose for successful treatment.
Buserelin | |||
| Active substance: | |||
| Treatment method: | Intramuscular injections | Nasal spray | |
| Set: |
| 17.5 ml dark glass bottle with sprayer | |
| Buserelin acetate: | |||
| Excipients: |
| benzalkonium chloride and water for injection | |
| Solvent: 0.8% Mannitol solution | in 1 ml water for injection | in 2 ml water for injection | |
| Released: | Requires a doctor's prescription |
||
| Storage conditions: | Temperature no more than 25°C |
||
| Shelf life: | Bottle with lyophilisate – no more than 2 years Ampoule with solvent – 3 years | Bottle with lyophilisate – no more than 3 years Ampoule with solvent – 5 years | Up to 3 years |
Each drug is developed and manufactured according to certain technologies and principles. The substances included in its composition may produce undesirable results in combination with other pharmaceuticals. Preparations containing buserelin cannot be used in parallel with medications that lower blood sugar levels and sex hormones (when stimulating ovulation).
For what diseases can Buserelin be prescribed?
Treatment with this drug is carried out for pathological diseases of the reproductive system:
- uterine fibroids;
- hyperplastic changes in the endometrium;
- ovarian tumors;
- mammary cancer;
- prostate cancer.
The drug Buserelin has proven itself well in the treatment of infertility using in vitro fertilization. It suppresses the work of the woman’s hormonal system and makes it possible to artificially control the processes of egg maturation, fertilization and implantation in the uterus. This helps a woman to become pregnant successfully.
What happens in the body under the influence of Buserelin
Buserelin is a synthetic analogue of gonadotropin-releasing hormone (abbreviated as GnRH). It is a stimulating hormone and effectively stimulates the pituitary gland. The active work of this endocrine gland turns off the production of follicle-stimulating and luteinizing hormones and completely stops ovulation in women. During treatment, the content of estradiol in the blood is very low - at the level of postmenopausal values, and the physical and psychological state of patients corresponds to the period of sexual decline (mood swings, hot flashes and palpitations).
Under what circumstances is the medicine contraindicated?
The drug Buserelin cannot be taken independently (without a doctor’s prescription). The doctor will definitely check the amount of hormones in the blood, conduct an ultrasound examination of the internal organs and other necessary tests.
A hormonal drug containing the substance buserelin is not prescribed if:
- The woman is pregnant. Using the medicine while carrying a child can lead to a delay in the development of the embryo or miscarriage. Immediately after childbirth, you should also not undergo treatment if the woman is breastfeeding. The drug has the ability to penetrate into milk and affect the baby.
- A woman has entered menopause.
- The patient is experiencing a period of depression. Taking Buserelin can worsen the psychological state.
- The diagnosis is: diabetes or high blood pressure. In these diseases, blood vessels become fragile and cannot withstand additional stress.
- The patient has not reached puberty (so as not to destroy the developing hormonal background).
- In case of individual intolerance to the components of the drug.
How does the body as a whole react to treatment?
The brain controls all processes within a person, producing certain hormones. Any interference in this complex process causes deviations in the functioning of all organs. That is why Buserelin is taken only under the supervision of a doctor: in order to monitor and promptly minimize negative manifestations. Patients describe the following side effects:
| Among women | In men |
| Depression, insomnia, tearfulness | Exacerbation and intensification of the underlying disease, severe bone pain |
| Headache | Muscle weakness in the legs |
| Vaginal dryness | Urinary retention |
| Decreased sexual desire | Decreased potency |
| Bleeding similar to menstrual bleeding (in the first weeks of use); pain in the lower abdomen | Gynecomastia (breast enlargement) |
| Tides | Swelling of the legs, face |
| Increased sweating | |
| Hyperemia (redness) of the skin | |
| Hives and other allergic reactions (including anaphylactic shock) | |
| Leaching of calcium from bones (leads to osteoporosis) | |
| High blood pressure and tachycardia (weak blood vessels may cause nosebleeds) | |
| The sense of smell deteriorates, vision becomes unclear and blurry | |
| Nausea and vomiting, diarrhea or constipation | |
| Loss of appetite (causes noticeable fluctuations in weight) |
Buserelin nasal spray
Endometriosis is most often treated with drops. They have a more affordable price than the drug for intramuscular administration. The daily norm (900 mcg) is divided into three doses. From one spray, the body receives 150 mcg of medication. The dosage regimen is as follows: one injection into each nostril three times a day. The nose must be clean so that all the medication reaches its intended destination. A runny nose is not a contraindication to treatment. The main thing is to keep your sinuses clean and open. To preliminary cleanse the nose of accumulated mucus, you can use saline solutions.
The main disadvantage of this form of administration is the exact adherence to time intervals. Between doses (injections) can take from 6 to 8 hours. Even your night's rest will have to be adjusted to accommodate your medication dosing schedule. The course lasts 3-6 months and, according to patients, requires a lot of patience and self-discipline.
Use of the drug in ampoules
In the form of injections, Buserelin therapy follows a simpler scheme than a spray: an intramuscular injection is given every 28 days. For each diagnosis, there is a specific method of taking the drug:
- If treatment is being carried out for endometriosis, uterine fibroids or endometrial hyperplastic processes, the first injection is given between 1 and 5 days from the start of menstruation. Subsequent injections are given at intervals of 4 weeks. The course of therapy is from 3 to 6 months.
- Men with prostate cancer and women with breast cancer are prescribed injections according to a similar scheme.
- When treating infertility or in preparation for IVF, the first injection can be done on the second day of the cycle (the follicular phase is just beginning) or in the period from 21 to 24 days (the luteal phase in the middle). 2 weeks after the administration of the medication, the amount of estrogen in the blood plasma is reduced by half, and if an ultrasound examination does not show problems in the uterus and ovaries in the form of a cyst, the doctor prescribes stimulation of the ovulation process (gonadotropic hormones are used). This complex procedure is performed under ultrasound monitoring. During therapy, the level of estradiol is constantly monitored, and the doctor can change the dose of Buserelin depending on the situation.
How to prepare solution for injection
The pharmaceutical packaging of the drug for intramuscular administration contains a pair of bottles and a syringe with two needles. One bottle contains the drug, and the second contains the solvent. Needles are needed: one for mixing the medicine, the other for injection. The solvent is drawn up with a syringe and injected into the capsule with the main suspension. The mixture should be shaken thoroughly and the drug should be allowed to completely dissolve. The needle on the syringe is then changed and the injection can be performed.
Total analogues: 13. Price and availability of analogues of Buserelin in pharmacies. Before using any medication, you should always consult your doctor.The medication is prepared immediately before administration into the body strictly according to the instructions. To avoid accidents during intramuscular injection, the injection should be done in a treatment room.
This page provides a list Buserelin analogues- these are interchangeable drugs that have similar indications for use and belong to the same pharmacological group. Before you buy analogue of Buserelin, it is necessary to consult with a specialist regarding replacement of the drug, study in detail, read and a similar drug.
Endorm
A drug Endorm shown when:
- Hypothyroidism
- Hyperthyroidism (thyrotoxicosis)
- Autoimmune thyroiditis
- Euthyroid goiter (diffuse, nodular, multinodular)
- Endemic goiter
- Prevention of thyroid diseases
- Menopausal syndrome
- Complex treatment of hyperplastic diseases of the female reproductive system (mastopathy, endometriosis, endometrial hyperplasia, etc.)
- Comprehensive treatment of metabolic syndromeGinecol Evalar
Gynecol- a biologically active food supplement - an additional source of arbutin, salidroside - the main active substances that, acting in combination, help maintain a woman’s reproductive health and prevent the exacerbation of inflammatory diseases of the genitourinary system.
Vitazenova
Vitazenova recommended as a dietary supplement for women - an additional source of vitamins: B1, B2, B5, B6, B12, E, A, PP, D3, K, folic acid, biotin, coenzyme Q10; magnesium, iron, zinc, manganese, copper.
The drug Vitazenova is a dietary supplement, a vitamin and mineral complex, which promotes the normal course of physiological processes in the body and maintains a woman’s reproductive health.
Emzenova
A drug Emzenova recommended as a dietary supplement for women - a source of isoflavones, an additional source of vitamins B1, B6 and B12, magnesium, iron, zinc, selenium, glutathione.
Bust-Formula Forte
Bust-Formula Forte It is recommended to use as a dietary supplement to the diet for women. Helps normalize the functions of the genital organs and the condition of the mammary glands with symptoms associated with an imbalance of female sex hormones (premenstrual syndrome, mastopathy, endometriosis, uterine fibroids, menopausal disorders).
Can be used for correction of the mammary glands (increasing breast firmness, tone and elasticity, including after childbirth), and for papillomavirus infection.
Reduces the risk of complications when undergoing hormone replacement therapy.
KOENO QHL
SOLGAR BERRIES WITH PALMETTO
DETRIMAX
SERENOA
PROXIDE WOMAN
INOFOLIK
Quinol
Quinol used for diseases of the female reproductive system, the development of which is based on the processes of pathological cell proliferation.
Quinol can be used to prevent hormonal disorders and hormone-dependent diseases:
- Mastopathy;
- Endometriosis, adenomyosis;
- Myoma (fibromyoma) of the uterus;
- Ovarian cysts;
- Cervical dysplasia;
- Premenstrual syndrome;
- Papillomatosis of the female reproductive system, human papillomavirus infection (papillomas, genital warts).Stella
A drug Stella recommended as an adjunct in the complex therapy of hormone-dependent diseases of the female reproductive system: uterine fibroids, fibrocystic mastopathy, cervical dysplasia, endometriosis, endometrial hyperplasia, etc. in order to normalize estrogen metabolism.
In the prevention of recurrence (recurrence of the disease) of fibroadenomas after surgical treatment.
To reduce the risk of hormone-dependent diseases of the female reproductive system (uterine fibroids, fibrocystic mastopathy, cervical dysplasia, endometriosis, endometrial hyperplasia, etc.).
In the prevention of diseases associated with the human papillomavirus (HPV), such as cervical dysplasia, genital warts, papillomatosis, as well as in the prevention of cervical cancer and breast cancer.
As a means of improving the functional state of the female reproductive system.
