Home Oral cavity Fluomizin: instructions for use of vaginal tablets. Fluomizin analogues and prices Terms and conditions of storage

Oral cavity

Fluomizin: instructions for use of vaginal tablets. Fluomizin analogues and prices Terms and conditions of storage

Vaginal tablets - 1 tab.:

active substance: dequalinium chloride - 10 mg;
excipients: lactose monohydrate; MCC; magnesium stearate.

Vaginal tablets, 10 mg. 6 tab. in blisters made of aluminum and PVC foil.

1 blister pack is placed in a pack of cardboard.

Description of the dosage form

Tablets are white, oval, biconvex.

pharmachologic effect

Antiseptic.

Pharmacokinetics

With intravaginal administration, an extremely small amount of dequalinium chloride is absorbed through the vaginal mucosa into the systemic circulation, metabolized to a 2,2-dicarboxylic acid derivative and excreted in an unconjugated form through the intestines.

Pharmacodynamics

Fluomizin® contains the active substance dequalinium chloride, which is a quaternary ammonium compound with a broad spectrum of antimicrobial activity. Dequalinium chloride is active against most gram-positive Streptococcus spp. gram-negative bacteria Gardnerella vaginalis, Escherichia coli, Serratia spp., Klebsiella spp., Pseudomonas spp., Proteus spp. and protozoa (Trichomonas vaginalis).

Indications for use Fluomizin

bacterial vaginosis;
candidal vaginitis;
trichomonas vaginitis;
sanitation of the vagina before gynecological operations and childbirth.

Contraindications for the use of Fluomizin

hypersensitivity to the components of the drug;
ulcerative lesions of the epithelium of the vagina and cervix.

Fluomizin Use in pregnancy and children

The drug is approved for use during the entire period of pregnancy and lactation.

Fluomizin side effects

Very rarely, local reactions of irritation (erosion), itching, burning or redness of the vaginal mucosa can be observed. However, these adverse reactions may also be associated with symptoms of a vaginal infection.

Extremely rarely - fever, allergic reactions.

drug interaction

Fluomizin® is incompatible with soap and other anionic surfactants.

Dosage of Fluomizin

During menstruation, treatment should be stopped and the previous course should be continued after it has ended.

It is necessary to carry out a full course of treatment (6 days) in order to avoid relapse.

Overdose

There are no data on overdose. With intravaginal use, overdose is unlikely.

Precautionary measures

Fluomizin® contains excipients that sometimes do not completely dissolve in the vagina. Therefore, the remains of the vaginal tablet can be found on the underwear. This does not affect the effectiveness of Fluomizin®.

In rare cases, with excessive dryness of the vagina, there is a chance that the tablet will remain undissolved. To prevent this, before inserting a vaginal tablet, it must be moistened with water (for 1 s under running water).

During the treatment period, it is recommended to change pads and underwear more often. If clinical signs of infection persist after completion of treatment, a repeat microbiological examination should be performed to identify the pathogen and confirm the diagnosis.

Influence on the ability to drive a car or perform work that requires an increased speed of physical and mental reactions. The drug does not affect the performance of potentially hazardous activities that require special attention and speed of psychomotor reactions (driving a car, etc.).

For the treatment inside the vagina of many common female diseases, the use of a drug such as Fluomizin suppositories is prescribed. They have an antiseptic and antimicrobial effect, are approved for use during pregnancy. Fluomizin is injected directly into the vagina. This drug is used as prescribed by a doctor, independent use is not recommended.

What is fluomizin suppositories

Fluomizin is an oval vaginal tablet (6 pcs/blister) packed in a cardboard box with attached instructions for use. The active substance of the drug is dequalinium chloride. It is prescribed for the treatment of female infections as prescribed by a gynecologist. Before purchasing the product, you need to consult a doctor, only he can determine the diagnosis, decide on the appointment of suppositories and set the required dosage.

Compound

Consider the composition of Fluomizin suppositories, which provides an antiseptic and antimicrobial effect. The active substance is the main component that fights microorganisms that cause certain diseases. To simplify the introduction, manufacturers add excipients. These components are not always completely dissolved by the secretion of the vaginal glands, which must be taken into account when using the drug. The composition of the candles Fluomizin:

active substance - dequalinium chloride 10 mg for each vaginal tablet;
lactose monohydrate;
microcrystalline cellulose;
magnesium salt of stearic acid.

pharmachologic effect

Dequalinium chloride is a compound of the fourth ammonium, which has a wide spectrum of antimicrobial activity. It is used to combat gram-positive infections: streptococcus (golden, beta-hemolytic groups A, B, D, peptostreptococci and others), listeria. Dequalinium chloride is also used to treat diseases in gynecology caused by gram-negative microbes: E. coli, serrations, proteas, bacteroids, pseudomonads, gardnerella, fusobacteria. It is also active against yeast-like fungi Candida and Trichomonas.

Upon contact with the site of action, the active substance included in the Fluomizin suppositories dissolves in secret at a concentration of 4000-2000 mg / l, while the minimum concentration for microbes is 90 mg / l. The main part of the drug is excreted naturally. The residue, overcoming the mucosal barrier, enters the bloodstream, is metabolized into a sulfuric acid derivative and excreted through the intestines. Two days after application, the swelling of tissues and mucous membranes becomes less, the amount of discharge decreases.

Indications for use

Fluomizin suppositories are used for antiseptic purposes: they treat infectious diseases, fungi. It is prescribed for gynecological problems such as candidal vaginitis, bacterial vaginosis, trichomoniasis. The drug Fluomizin is used for prophylactic purposes: immediately a few hours before childbirth or an operation to disinfect the intravaginal area. Let us consider in more detail the two main reasons for which Fluomizin suppositories are prescribed. This is thrush and colpitis.

With thrush

Thrush is a common female disease caused by a fungus of the Candida group. It does not cause harm to health, but brings a lot of uncomfortable sensations: itching, burning appear in the genital area, white curd discharge appears. If at the first signs of thrush it is not treated, it develops into a chronic disease, which subsequently manifests itself when the immune system is weakened, for example, after a cold. Fluomizin suppositories for thrush, which are included in complex treatment, are one of the remedies that successfully fight this problem.

With colpitis

Inflammation of the female appendages is called colpitis. It is caused by pathogenic bacteria that enter the vagina and become active when the body loses some of its protective functions. The disease without treatment quickly spreads to the cervix, the uterus itself and the ovaries. In the future, the influence of the disease can be detected in infertility, ectopic pregnancy, tumors and other consequences. Therapy for colpitis consists of taking pills, using suppositories, including Fluomizin, and a number of procedures. Candles Fluomizin for colpitis are prescribed only by a doctor.

Instructions for use

Fluomizin suppositories are prescribed by the attending gynecologist, but they can be purchased at a pharmacy without a prescription. Before use, be sure to read the instructions for use enclosed in the carton. For treatment, one suppository is inserted into the vagina just before bedtime. The course of treatment is 2 weeks. During menstruation, a break should be taken in treatment and therapy should be continued at the end of women's days. As for preventive measures before surgery and childbirth, here the dosage is set by the gynecologist individually.

During pregnancy

The results of the study showed that Fluomizin vaginal tablets do not affect the development of the fetus or the child who is breastfed. Treatment occurs without any undesirable effects and other factors that may negatively affect the mother and the baby during the feeding period. The dosage and duration of treatment during this period is prescribed by the doctor after passing the tests. It is forbidden to use the drug without his permission.

In the first trimester

The first trimester is the period of pregnancy when the baby's organs are deposited. At this time, it is worth treating all medicines as carefully as possible, this also applies to this drug. Fluomizin suppositories during pregnancy are prescribed only by a doctor, and in the case when the consequences of the disease for the fetus and woman exceed the possible consequences from the use of the drug.

How to insert Fluomizin correctly

Fluomizin is inserted directly into the vagina. In some cases, the excipients that make up the vaginal tablets are not completely absorbed by the body, and some of them come out in the form of copious secretions. This is a normal consequence of using candles. At night, it is recommended to wear thick cotton underwear and use sanitary pads to avoid staining. Consider step by step how to properly carry out the procedure so that the treatment is effective:

Before the procedure, you need to thoroughly wash your hands, lie on your side, bending your knees to your chest.
Gently insert the candle inside. If the insertion causes discomfort due to dryness in the vagina, it is recommended to first dip the vaginal tablet in warm water for a few seconds.
Complete the procedure. It is impossible to get up after the introduction, otherwise the dissolved suppository may leak out ahead of time, and the effect of the treatment will be incomplete.

Burning after Fluomizin

After the introduction of the Fluomizin suppository, a slight burning sensation will be felt after three to five minutes: this is normal, so there is no need to worry. If the burning sensation is unbearable, then you should make an enema of clean boiled water to wash the remnants of the pill from the vagina, and consult a doctor in the morning. This may cause an allergic reaction to the drug. If burning accompanies swelling and itching of the mucosa, you should consult a doctor. Most likely, he will prescribe an antihistamine drug, for example, Suprastin or Diazolin.

Side effects

Burning is the main side effect of Fluomizin suppositories. There may be rashes and itching on the skin at the site of use. Sometimes there are local irritant reactions similar to erosion: this is due to inflammation due to infection or a lack of the hormone estrogen. In very rare cases, patients who are treated with Fluomizin suppositories complain of fever and chills.

Contraindications

Before using Fluomizin suppositories, it is imperative to study the instructions, which will indicate contraindications. This drug is not intended for children and girls who have not reached reproductive age. Fluomizin suppositories are contraindicated in women with diagnosed ulcers of the cervix and vaginal epithelium or other violations of the integrity of the vaginal mucosa.

Candles can not be used by those who have had an allergic reaction to the drug or have been found to have individual intolerance to dequalinium chloride or the auxiliary components of Fluomizin suppositories. The drug can be taken by those women who drive a car or are engaged in work that requires increased attention and concentration. There are no data from clinical studies on the interaction of the drug with alcohol.

drug interaction

The interaction of Fluomizin suppositories for intravaginal use with other drugs has not been identified. If a woman is taking other medicines at the time of treatment with this drug, then her gynecologist should be informed about this. The drug Fluomizin is not compatible only with anionic active substances, that is, soap. Doctors do not recommend washing with soap later than an hour before the injection.

Analogues

You cannot find drugs similar in composition, however, there are drugs whose pharmacological actions are similar to Fluimizin. These include Hexicon, Livarol, Zalain, Klion, Macmirror and others. Consider in more detail a few analogs:

Hexicon. These are antiseptic suppositories, the active ingredient of which is chlorhexidine bigluconate. The agent is active against most gram-positive and gram-negative types of bacteria. It is prescribed for ureaplasma, trichomoniasis, gonorrhea, chlamydia and other infectious diseases. Used before childbirth or surgery, as an emergency remedy after unprotected intercourse.
Livarol. Livarol is an antifungal vaginal suppository. The active substance here is ketoconazole. These suppositories are prescribed for thrush in acute and chronic form, with mixed infections, during a violation of the vaginal microflora. They are recommended for long-term use of antibiotics.
Zalain. These candles are antifungal agents that also have an antiseptic effect. They are prescribed for thrush and other infections. The active substance of Zalain is sertaconosole nitrate. Instructions for use of this drug are similar to Fluomizin. Also available as a cream.

Latin name: Fluomizin
ATX code: G01AC05
Active substance: Dequalinium chloride
Manufacturer: Rottendorf Pharma, Germany
Pharmacy leave condition: Over the counter

Fluomizin is an antiseptic drug used in gynecology for the treatment of infectious diseases.

Indications for use

Vaginal tablets are prescribed for use with:

Vaginitis caused by Trichomonas
Vaginitis caused by Candida (thrush)
Vaginosis of bacterial origin.

Also, the use of Fluomizin is possible for the purpose of sanitation of the genital tract before delivery or surgery.

Compound

Fluomizin tablets contain a monocomponent - dequalinium chloride. Its mass fraction in one tablet is 10 mg.

Additionally present:

Lactose monohydrate
Magnesium stearate
Cellulose microcrystalline.

Medicinal properties

Dequalinium chloride refers to ammonium compounds that have the widest antimicrobial spectrum. This drug is active against gram-positive pathogenic microorganisms, and in particular staphylococci (activity is observed against β-hemolytic strains A, B), listeria, peptostreptococci, Staphylococcus aureus, Candida yeast; gram-negative pathogenic microorganisms - E. coli, gardnerella.

The drug inhibits the vital activity of Pseudomonas, Serration, Klebsiella, Proteus, Trichomonas.

With intravaginal use, a small amount of the active component of vaginal suppositories enters the general circulation, undergoes a transformation process and is converted into dicarboxylic acid. Excretion of metabolic products is carried out by the intestines.

Release form

Fluomizin 10 is presented in oval-shaped tablets of a creamy white hue. Tablets (6 pcs.) are placed in a blister pack. The pack contains 1 pack of Fluomizin and instructions for use.

Features of treatment with Fluomizin

Price: from 677 to 1020 rubles.

The use of vaginal tablets can only be started after consultation with a specialist.

The introduction of a vaginal tablet is carried out in the supine position with bent legs (preferably at bedtime). The tablet should be taken once a day.

In the event of the onset of menstruation, it is recommended to interrupt the treatment started and continue after the disappearance of spotting. The duration of therapy is 6 days, this will be enough to prevent the occurrence of relapse. Fluomizin suppositories for thrush are prescribed for use according to the standard scheme.

It is worth using additional creams and ointments only after consulting a gynecologist.

Use during pregnancy and breastfeeding

Fluomizin suppositories during pregnancy are usually not prescribed, since there is no data on the use of this drug in the 1st and 2nd trimesters. But pregnancy is not an absolute contraindication to the use of the drug. It is worth noting that the 1st trimester of pregnancy is a very important period in the development of the embryo, the use of any drugs should take place only after consultation with a gynecologist. If you have been prescribed the use of these suppositories in the first trimester, you should strictly follow the instructions and do not exceed the recommended dose.

These suppositories can be prescribed for sanitation of the genital tract immediately before childbirth. In this case, Fluomizin suppositories during pregnancy will prevent infection of the child during childbirth.

If it becomes necessary to carry out treatment during the period of breastfeeding, it is worth stopping breastfeeding.

Contraindications

The prescribed drug should not be used if:

Erosion of the cervix or other ulcerative lesions of the epithelial layer of the vagina (with erosion, the risk of complications is high)
Excessive susceptibility to Fluomizin (components contained in tablets).

It is contraindicated to use the drug in suppositories before the onset of sexual relations.

Precautionary measures

During the use of vaginal suppositories, uncharacteristic discharge may be observed (a few hours after using Fluomizin), this is due to the incomplete dissolution of the components of the drug inside the vagina. If a small amount of the drug flows out of the genital tract, this is acceptable. Although the suppositories leak, this in no way affects the effectiveness of the treatment. If the suppository leaks some time after insertion, sanitary pads must be used. After completion of therapy, the amount of discharge will decrease significantly.

If the walls of the vagina are dry, the tablet may not dissolve completely, therefore, before use, it must be well moistened with water (hold under running water for 1 second).

If, after the course of treatment, a burning sensation is felt and when the underwear is replaced, there is a discharge, as before therapy, a microbiological analysis will be required. If you have such symptoms after using Fluomizin, you should consult a doctor.

When using candles, you should refrain from sexual intercourse.

It is worth noting that men need to undergo parallel treatment with a partner. If there have been sexual contacts before, it is most likely that the partner also has an infectious agent.

Cross-drug interactions

Intimate hygiene after using Fluomizin should be gentle, it is worth completely eliminating the use of soap and other anionic surfactants.

Alcohol compatibility

It is undesirable to drink alcohol during the use of candles, the effectiveness of the therapy may decrease.

Side effects

After using Fluomizin, local reactions may occur, namely:

Irritation that can develop into erosion
severe itching
Hyperemia of the mucous membranes.

It is worth noting that the presence of burning and redness on the first day of using the drug may be associated with symptoms of a vaginal infection (for example, candidiasis) or even cystitis.

Quite rarely, there is a development of fever, the appearance of an allergy after using Fluomizin.

With severe adverse reactions, it is worth deciding whether to replace the drug with another, for example, an ointment. The doctor will help you choose a medicine to replace antibacterial suppositories, he will tell you what is best suited in a particular case.

Overdose

When using suppositories, the risk of overdose is minimal.

Storage conditions and shelf life

Analogues

Sofartex, France

Price from 320 to 857 rubles.

Terzhinan refers to antimicrobial agents with a combined composition, used to treat infectious gynecological ailments. The active ingredients of Terzhinan are neomycin, prednisolone, and ternidazole. Terzhinan is available in the form of vaginal tablets.

Pros:

High efficiency
Low price for Terzhinan
Ease of use.

Minuses:

Can only be purchased with a prescription
Allergic reactions not excluded
Terzhinan is not recommended for children under 16 years of age.

Nizhpharm, Russia

Price from 41 to 325 rubles.

Hexicon is an antiseptic and disinfectant that is used to treat various gynecological diseases. The active ingredient of Hexicon is chlorhexidine bigluconate. The drug is produced in the form of candles.

Pros:

low price
Can be used during menstruation
Allowed during pregnancy, GV.

Minuses:

Often provokes allergic reactions
Prescribed with caution to children
Do not combine with vaginal suppositories containing iodine.

Candles "Fluomizin" is a tool that women are forced to deal with more and more often, since infections in gynecology are especially pronounced. The appearance of pathogenic flora is caused by various reasons. Against the background of reduced immunity, deep and frequent stress, infections and fungi occur in the intimate area.

The composition of the candles "Fluomizin", release form, packaging

The drug is produced in the form of white vaginal tablets, biconvex and oval. The active ingredient in one piece is 10 milligrams of dequalinium chloride.

Auxiliary components: lactose monohydrate, magnesium stearate, microcrystalline cellulose. In blister packs of six suppositories.

Why are Fluomizin suppositories prescribed?

Indications

Vaginal tablets are prescribed for:

vaginal sanitation before childbirth and gynecological operations;
trichomonas vaginitis;
candidal vaginitis;
bacterial vaginosis.

The drug must be prescribed by a doctor.

Instructions for use of suppositories

Instructions for the use of candles "Fluomizin" is very simple. One tablet is used once a day. It must be inserted into the vaginal cavity as deep as possible, preferably in the evening, just before going to bed, while bending your legs and lying on your back.

It should be noted that in general, six days and six tablets are enough, respectively. Such a treatment period allows you to completely eliminate violations in the body. Just taking the drug correctly is not enough, you also need to pay attention to side effects.

Side effects

What else does the instructions for use for Fluomizin candles tell us?

The drug has side effects, you need to carefully read the instructions before using it.

These include the following symptoms:

burning;
fever;
mucosal redness.

Contraindications

Fluomizin vaginal tablets also have a number of contraindications, which include:

excessive sensitivity;
inflammation on the cavity of the uterine neck;
ulcerative lesions on the cavity of the vaginal epithelium.

It is undesirable to use dequalinium chloride before the start of an intimate life. But it is strictly forbidden to use the drug even with severe thrush for the following categories of patients:

The drug has a simple mechanism of action, since its components affect pathogenic bacteria, killing them and thereby normalizing the activity of the reproductive system. It has already been said that it is not recommended to use the remedy during menstruation, since blood discharge will remove the remedy immediately after administration, it dissolves at a high speed. The drug is used during lactation and pregnancy only if there are serious indications and only after passing all the tests that allow you to accurately establish the disease and its severity.

We continue to consider the instructions for use in gynecology of the Fluomizin suppositories.

The use of tablets during pregnancy

Doctors believe that during pregnancy it is best to avoid drugs such as alcohol, antibiotics, foods that can harm health, cheap vitamins.

It is during pregnancy that the female body is not only weakened, but also needs only useful substances that improve the functioning of all its systems and do not affect the child. Against the background of hormonal changes occurring in the body, the flora of the reproductive system changes, which causes the formation of a sexual infection, especially if a woman has several intimate partners at the same time.

Regardless of which trimester, Fluomizin suppositories are allowed to be used by pregnant women only after consultation with a gynecologist. It must be remembered that it is one of those drugs that are allowed when carrying a baby, even in the treatment of the following disorders in the body: vaginitis, chlamydia, thrush.

It is during pregnancy that only vaginal tablets are used. The composition of one candle contains 10 milligrams of such an important substance as dequalinium chloride.

In accordance with the instructions for use, Fluomizin suppositories are used for:

The drug begins to act immediately after the introduction into the vaginal cavity, the absorption of the mucosa is carried out in a minimal amount, which excludes the ingress of the substance into the blood and the fetus.

special instructions

It should be noted that there are special instructions for the use of Fluomizin vaginal tablets.

Small secretions do not need to be scared, because the drug has several auxiliary components that cannot dissolve in the vaginal cavity. This circumstance does not reduce the effectiveness of the drug.

In such a condition in a woman as vaginal dryness, it is recommended to moisten the tablets with water before use.

Throughout the course of treatment, you need to use special sanitary pads, they need to be changed more often than usual, in addition, thanks to this, underwear will not be damaged.

With the remaining disorders of the reproductive system after treatment, it is recommended to conduct a repeated microbiological analysis, which will determine the problem and make a more accurate diagnosis.

To prevent urogenital infection, it is recommended that both partners be treated simultaneously.

The appointment is carried out exclusively by a specialist and only after taking a smear; conducting the necessary research; confirmation of the diagnosis.

This is confirmed by the instructions for use for candles "Fluomizin".

Drug analogues

For some women, it is much easier to use not tablets and suppositories, but ointment, in addition, the cost of medicines and composition features are important. Some patients are looking for cheaper drugs, while others, on the contrary, are more expensive. In general, to replace Fluomizin, you can use analogues - both expensive and cheap, but they must have the same composition as the original drug.

You can replace "Fluomizin" with the following means: "Terzhinan"; "Candide B6"; "Hexicon"; "Vagitsin"; "Livarol"; "Ketoconazole"; "Zalain"; "Vagisept"; "Gynoflor"; "Pimafucin" and others.

"Utrozhestan" is not among the analogues. It is undesirable to carry out replacement on your own, you should consult with a specialist.

Analogues are cheaper

Candles "Fluomizin" are an expensive remedy. Cheaper analogues can be used as a replacement, but you must first agree on your choice with your doctor. Let's describe some of them.

"Hexicon"

Antiviral antifungal antiseptic, which produces an antibacterial effect on gram-negative, gram-positive microorganisms, inhibits the activity of yeast-like fungi and chlamydia.

The active ingredient in the preparation is chlorhexidine bigluconate. The excipient is corn starch. "Hexicon" is the cheapest substitute for Fluomizin vaginal suppositories, which has an identical release form - vaginal torpedo-shaped biconvex tablets; vaginal suppositories.

"Hexicon" does not have a negative effect on the vaginal microflora, however, prolonged use can cause resistance of viruses and bacteria to it. In particular, in the treatment of purulent infection, the active substance can significantly reduce its activity.

The drug in accordance with the instructions is used in the treatment of:

exocervicitis;
vaginal dysbacteriosis;
vaginitis (trichomonas, nonspecific, mixed);
with a preventive purpose to prevent sexually transmitted diseases (trichomoniasis, genital herpes, gonorrhea, syphilis, ureaplasmosis);
before childbirth or abortion, the installation of a spiral inside the uterus.

Contraindications:

allergic reactions;
hypersensitivity to the active ingredient.

It can be prescribed to girls before the onset of sexual activity only with the permission of the gynecologist.

Undesirable manifestations (irritation of the vulva, burning, itching) are rare, but if they occur, the drug must be replaced.

"Hexicon" is a cheap analogue of "Fluomizin", which is quite capable of replacing it in case of infection in the urogenital tract. Price - from 250 to 300 rubles.

Antifungal agent "Zalain"

An analogue with the same release form as that of Fluomizin is vaginal suppositories in blisters. The active substance of the composition is sertaconazole nitrate. Auxiliary components: silicon dioxide, colloidal suppocir, witepsol.

The active substance sertaconazole (this is a derivative of benzothiophene, imidazole) has a fungicidal, fungistatic effect. Analogue "Zalain" is often prescribed by gynecologists for a depressing effect on infectious pathogens that provoke the development of sexually transmitted diseases and lead to lesions of the vaginal mucosa (skin).

The active substance sertaconazole in the composition of the product is active against staphylococci, dermatophytes and streptococci. At the heart of its action is the inhibition of the synthesis of ergosterol in the membrane structures of yeast-like bacteria and fungi. The drug is prescribed for candidal vulvovaginitis, that is, infection of the vaginal mucosa with Candida fungi.

The agent is not prescribed for intolerance to the composition. Women during lactation and pregnancy only with a higher benefit than harm to the baby or fetus. It is also a cheap analogue - about 500 rubles.

The drug "Livarol"

A cheap analogue, topical antifungal drug in gynecology, intended for the treatment of infectious fungal infections that are sensitive to the active substance.

The tool is available in the form of torpedo-shaped candles. The active ingredient is ketoconazole, that is, an imidazoledioxolane derivative, which has a fungistatic, fungicidal effect, suppressing the reproduction and growth of a fungal infection.

Excipients: macrogol 1500, butylhydroxyanisole, macrogol 400.

The agent is an analogue that actively inhibits ergosterol synthesis in the intercellular space of microorganisms (streptococci, yeast fungi, dermatophytes, staphylococci).

Indications for use:

It should be noted that Livarol suppositories may be useless in the treatment of bacterial vaginosis. Before using the drug or if side effects occur, you should consult a gynecologist.

Contraindications:

first trimester of pregnancy;
children under twelve;
individual sensitivity.

In special cases, it is allowed in the second and third trimester of pregnancy. During breastfeeding - with caution. Means "Livarol" has a cost of 390 rubles.

Manufacturer
Country of origin
Product group
Description
Release forms
Description of the dosage form
pharmachologic effect
Pharmacokinetics
Special conditions
Compound
Fluomizin indications for use
Contraindications
Dosage
Side effects
drug interaction
Overdose
Storage conditions

Manufacturer

Medinova Ltd

Country of origin

Switzerland

Product group

Antibacterial drugs

Antiseptic for local use in gynecology

Release forms

6 - cellular contour packs (1) - packs of cardboard.

Description of the dosage form

Vaginal tablets, white, oval, biconvex

pharmachologic effect

Antiseptic for local use in gynecology.

uomizin contains the active substance dequalinium chloride, which is a quaternary ammonium compound with a broad spectrum of antimicrobial activity. Dequalinium chloride is active against gram-positive bacteria: Streptococcus spp., including beta-hemolytic streptococci of groups A and B, Staphylococcus aureus, Listeria spp.; anaerobes: Peptostreptococcus (group D); fungi of the genus Candida (Candida tropicalis, Candida albicans, Candida glabrata); Gram-negative bacteria: Gardnerella vaginalis, Escherichia coli, Serratia spp., Klebsiella spp., Pseudomonas spp., Proteus spp.; protozoa: Trichomonas vaginalis.

Pharmacokinetics

With intravaginal administration, a very small amount of dequalinium chloride is absorbed through the vaginal mucosa into the systemic circulation, metabolized to a 2,2-dicarboxylic acid derivative and excreted in an unconjugated form through the intestines.

Special conditions

Fluomizin contains excipients that sometimes do not completely dissolve in the vagina. Therefore, the remains of the vaginal tablet can be found on the underwear. This does not affect the effectiveness of Fluomizin. In rare cases, with excessive dryness of the vagina, there is a chance that the tablet will remain undissolved. Therefore, before inserting a vaginal tablet, it must be moistened with water (for 1 second under running water). During the treatment period, it is recommended to change pads and underwear frequently. If clinical signs of infection persist after completion of treatment, a repeat microbiological examination should be performed to identify the pathogen and confirm the diagnosis.

the period of treatment with the drug is recommended to refrain from sexual intercourse. To prevent urogenital reinfection, simultaneous treatment of sexual partners is necessary. Influence on the ability to drive vehicles and control mechanisms The drug does not affect the performance of potentially hazardous activities that require special attention and speed of psychomotor reactions (driving a car).

Compound

dequalinium chloride 10 mg Excipients: lactose monohydrate, microcrystalline cellulose, magnesium stearate

Fluomizin indications for use

- bacterial vaginosis; - candidal vaginitis; - Trichomonas vaginitis; - Sanitation of the vagina before gynecological operations and childbirth.

Fluomizin contraindications

- ulcerative lesions of the epithelium of the vagina and cervix; - Hypersensitivity to the components of the drug. The use of dequalinium chloride before the onset of sexual activity is not recommended.

Fluomizin dosage

10 mg

Fluomizin side effects

Local reactions: very rarely - irritation (erosion), itching, burning or redness of the vaginal mucosa. However, these adverse reactions may also be associated with symptoms of a vaginal infection. Other: very rarely - fever, allergic reactions.

drug interaction

Fluomizin is incompatible with soap and other anionic surfactants

Overdose

There are no data on overdose. With intravaginal use, overdose is unlikely.

Storage conditions

store at room temperature 15-25 degrees
keep away from children

Information provided by the State Register of Medicines.

Indications for use

Vaginal tablets are prescribed for use with:

Vaginitis caused by Trichomonas
Vaginitis caused by Candida (thrush)
Vaginosis of bacterial origin.

Also, the use of Fluomizin is possible for the purpose of sanitation of the genital tract before delivery or surgery.

Compound

Fluomizin tablets contain a monocomponent - dequalinium chloride. Its mass fraction in one tablet is 10 mg.

Additionally present:

Lactose monohydrate
Magnesium stearate
Cellulose microcrystalline.

Medicinal properties

The drug inhibits the vital activity of Pseudomonas, Serration, Klebsiella, Proteus, Trichomonas.

Release form

Fluomizin 10 is presented in oval-shaped tablets of a creamy white hue. Tablets (6 pcs.) are placed in a blister pack. The pack contains 1 pack of Fluomizin and instructions for use.

Features of treatment with Fluomizin

The use of vaginal tablets can only be started after consultation with a specialist.

The introduction of a vaginal tablet is carried out in the supine position with bent legs (preferably at bedtime). The tablet should be taken once a day.

It is worth using additional creams and ointments only after consulting a gynecologist.

Use during pregnancy and breastfeeding

If it becomes necessary to carry out treatment during the period of breastfeeding, it is worth stopping breastfeeding.

Contraindications

The prescribed drug should not be used if:

Erosion of the cervix or other ulcerative lesions of the epithelial layer of the vagina (with erosion, the risk of complications is high)
Excessive susceptibility to Fluomizin (components contained in tablets).

It is contraindicated to use the drug in suppositories before the onset of sexual relations.

Precautionary measures

If the walls of the vagina are dry, the tablet may not dissolve completely, therefore, before use, it must be well moistened with water (hold under running water for 1 second).

When using candles, you should refrain from sexual intercourse.

It is worth noting that men need to undergo parallel treatment with a partner. If there have been sexual contacts before, it is most likely that the partner also has an infectious agent.

Cross-drug interactions

Intimate hygiene after using Fluomizin should be gentle, it is worth completely eliminating the use of soap and other anionic surfactants.

Alcohol compatibility

It is undesirable to drink alcohol during the use of candles, the effectiveness of the therapy may decrease.

Side effects

After using Fluomizin, local reactions may occur, namely:

Irritation that can develop into erosion
severe itching
Hyperemia of the mucous membranes.

It is worth noting that the presence of burning and redness on the first day of using the drug may be associated with symptoms of a vaginal infection (for example, candidiasis) or even cystitis.

Quite rarely, there is a development of fever, the appearance of an allergy after using Fluomizin.