Actovegin - analogues of the drug

Actovegin is a drug that normalizes tissue trophism, restoring the metabolic and conductive functions of tissues. After taking Actovegin, the nutrition of cells and tissues improves, allows the necessary substances to pass into the deep layers of the skin and optimize local blood circulation. But the price of the drug is not the most affordable.

How can you replace Actovegin and still get all the properties of Actovegin at a lower price?
the first analogue is Solcoseryl.

Solcoseryl analogue of Actovegin

Solcoseryl is also aimed at enhancing metabolic processes in the skin and regenerative processes on the skin. In addition, girls use solcoseryl due to its anti-aging properties.
Main properties of solcoseryl:
- Stimulation of collagen production in the skin;
-Improving the transport function of oxygen in tissue;
– Stimulation of cellular respiration;
– Activation of cell growth;
– Regeneration of small damaged vessels;
Solcoseryl is produced in several forms, this is due to ease of use. Dosage forms in which solcoseryl is produced:
– Ointment;
- Pills;
- Injection;
– Gel;
- Pasta.
Effective for necrotic lesions of the epidermis, for example, trophic ulcers, bedsores. Solcoseryl helps soften scar tissue and restore skin after a burn. Therefore, girls after caesarean section Solcoseryl can be lubricated on the skin in the incision area after a period of breastfeeding.
Solcoseryl in gel form has found application in ophthalmology. Damage to the cornea of ​​the eye, keratitis and eye injuries, the drug is able to heal the tissue and help a person forget the problem with the eye. The price of solcoseryl ranges from 230-1660 rubles.

Prices vary - this is due to the fact that different shape Solcoseryl costs differently. Another advantage is that solcoseryl is available without a prescription, so you don’t have to wait to see a doctor to get a prescription.

Curantil as an analogue of Actovegin

Curantil belongs to the group of antiplatelet agents and immunomodulators. Actovegin is considered an analogue due to its blood-thinning and vasodilating properties. Curantil improves blood microcirculation, is used for coronary heart disease, and is used as an interferon inducer for acute respiratory viral infections. The active ingredient of chimes is dipyridamole.
The price of chimes is about 575 rubles.
Main indications for the use of chimes:
– Treatment and prevention of ischemic cerebrovascular accidents;
- encephalopathy;
- primary and secondary prevention of coronary artery disease, especially in case of intolerance acetylsalicylic acid;
- prevention of arterial and venous thrombosis and treatment of their complications;
- prevention of thromboembolism after heart valve replacement surgery;
- prevention of placental insufficiency during complicated pregnancy;
- microcirculation disorders of any type (as part of complex therapy);
- prevention and treatment of influenza, ARVI (as an interferon inducer and immunomodulator) - for taking the drug in a dose of 25 mg.

But it is worth remembering the contraindications, these include:
– Angina pectoris during exacerbation;
– Acute myocardial infarction;
– Narrowing of the aorta and rhythm disturbance;
– Exacerbation of ulcers, peptic ulcer;
– Blockage of the lumen respiratory tract
The drug Actovegin can be replaced with chimes, provided that the doctor approves the replacement. You should not replace the drug on your own, because chimes has serious contraindications and the consequences can lead to an undesirable outcome. The cost of chimes is about 600 rubles, depending on the region the price may vary.

Cavinton and actovegin

Cavinton is aimed at improving cerebral circulation and metabolism in the brain.
Cavinton helps brain tissue consume glucose and oxygen, thereby reducing hypoxia in the tissues. Glucose passes through the blood-brain barrier to the brain without “effort.” It is classified as an analogue of Actovegin due to its similar properties. The active ingredient in Cavinton is vinpocetine and is a structural analogue of Actovegin active substance is not.

Indications for use of Cavinton:
– Chronic diseases cordially- vascular system;
- Decrease neurological symptoms at various forms ah cerebral circulatory insufficiency;
– Meniere's disease;
– Hearing loss and tinnitus.
Cavinton cannot be administered intramuscularly; it is produced in ampoules for intravenous administration and tablets.
The cost of Cavinton is about 400 rubles.

Mexidol as an analogue of Actovegin

Mexidol was also included in the list of Actovegin analogues because it has resistant properties to ischemia and cerebrovascular accidents. In addition, Mexidol has anti-stress, anticonvulsant, and nootropic properties. After taking Mexidol, the content of dopamine (the hormone of joy) in the brain increases, the sleep-wake balance is restored, and memory improves.

Cavinton indications for use

Vegetative dystonia;
– Encephalopathy of various origins;
– Traumatic brain injuries;
– Post-withdrawal disorder;
– Anxiety-phobic disorders;
– Ischemic disease hearts;
– Stressful conditions
The cost of Mexidol is not much cheaper than Actovegin, it is about 400 rubles. You should not replace one drug with another on your own.

Actovegin-medicinal product, which is a deproteinized hemodialysate containing wide range low molecular weight components of cell mass and blood serum of dairy calves with a molecular weight of up to 5000 daltons, the properties of which are currently only partially studied by chemical and pharmacological methods. Country Austria, manufacturer Nycomed.
Release form: gel 20% 20g in tube; cream 5% 20g in tube; ointment 5% 20g in tube; solution for injection with saline solution 4 mg/ml - 250 ml in a bottle, solution for injection with saline solution 8 mg/ml - 250 ml in a bottle, solution for injection 40 mg/ml - 2 ml in ampoules No. 10 and No. 25, solution for injection 40 mg /ml - 5ml in ampoules No. 5 and No. 10; injection solution 40 mg/ml - 10 ml in ampoules No. 5, tablets 200 mg No. 10 and No. 50.

Instructions for use of the drug Actovegin (official instructions)

Clinico - pharmacological group: A drug that activates tissue metabolism, improves trophism and stimulates the regeneration process.

Pharmachologic effect: An antihypoxant is a hemoderivat, which is obtained through dialysis and ultrafiltration (compounds with a molecular weight of less than 5000 daltons penetrate). Positively affects the transport and utilization of glucose, stimulates oxygen consumption (which leads to stabilization plasma membranes cells during ischemia and decreased lactate formation) thus providing an antihypoxic effect. Actovegin increases the concentrations of ATP, ADP, phosphocreatine, as well as amino acids (glutamate, aspartate) and GABA. The effect of the drug Actovegin on the absorption and utilization of oxygen, as well as insulin-like activity with stimulation of glucose transport and oxidation are significant in the treatment of diabetic polyneuropathy. In patients with diabetes mellitus and diabetic polyneuropathy, Actovegin significantly reduces the symptoms of polyneuropathy ( stabbing pain, burning sensation, paresthesia, numbness lower limbs). Sensitivity disorders are objectively reduced and the mental well-being of patients is improved. The effect of Actovegin begins to appear no later than 30 minutes (10-30 minutes) after parenteral administration and reaches a maximum, on average, after 3 hours (2-6 hours).

Pharmacokinetics: Using pharmacokinetic methods, it is impossible to study the pharmacokinetic characteristics (absorption, distribution, excretion) of the active components of the drug Actovegin, since it consists only of physiological components that are usually present in the body. To date, no decrease in the pharmacological effectiveness of hemoderivatives has been found in patients with altered pharmacokinetics (including hepatic or renal failure, metabolic changes associated with old age, due to the metabolic characteristics of newborns).

Indications for use of the drug Actovegin: metabolic and vascular disorders of the brain (including ischemic stroke, traumatic brain injury); peripheral (arterial and venous) vascular disorders and their consequences (arterial angiopathy, trophic ulcers); diabetic polyneuropathy; wound healing (ulcers of various etiologies, trophic disorders /bedsores/, burns, impaired wound healing processes); prevention and treatment of radiation injuries of the skin and mucous membranes during radiation therapy.

Dosage regimen:
Injection form: The solution for injection is administered intraarterially, intravenously (including in the form of infusion) and intramuscularly. The infusion rate is about 2 ml/min. The duration of treatment is determined individually, depending on the symptoms and severity of the disease. For ischemic stroke, 20-50 ml (800-2000 mg) of solution for injection is diluted in 200-300 ml of 0.9% sodium chloride solution or 5% dextrose solution and administered intravenously drip daily for 1 week, followed by 10-20 ml (400-800 mg) intravenously for 2 weeks and then switching to taking Actovegin in tablet form. For metabolic and vascular disorders of the brain, 5 to 20 ml of injection solution (200-800 mg/day) is administered intravenously for 2 weeks, followed by switching to Actovegin in tablet form. For peripheral (arterial and venous) vascular disorders and their consequences, administer 20-30 ml (800-1200 mg) of the drug in 200 ml of 0.9% sodium chloride solution or 5% dextrose solution intravenously or intravenously daily; Duration of treatment - 4 weeks. For diabetic polyneuropathy, administer 50 ml (2000 mg) per day intravenously for 3 weeks, followed by switching to taking the drug Actovegin in tablet form - 2-3 tablets 3 times a day for at least 4-5 months. For wound healing, 10 ml (400 mg) intravenously or 5 ml (200 mg) intramuscularly is administered daily or 3-4 times a week, depending on the healing process (in addition to local therapy with Actovegin in dosage forms for external use). For the purpose of prevention and treatment of radiation damage to the skin and mucous membranes, the average dose is 5 ml (200 mg) intravenously daily in the intervals between radiation exposure. For radiation cystitis, 10 ml (400 mg) is administered transurethrally daily in combination with antibiotic therapy. The rate of administration is about 2 ml/min. The duration of treatment is determined individually, depending on the symptoms and severity of the disease. The solution for infusion is administered intravenously or intravenously as a stream. The infusion rate is about 2 ml/min. The duration of treatment is determined individually, depending on the symptoms and severity of the disease. For ischemic stroke, 250-500 ml (1000-2000 mg) per day is administered intravenously for 2 weeks, followed by switching to taking the drug Actovegin in tablet form. For metabolic and vascular disorders of the brain, at the beginning of treatment - 250-500 ml (1000-2000 mg) per day intravenously for 2 weeks, followed by switching to taking the drug Actovegin in tablet form. For peripheral vascular disorders and their consequences, administer 250 ml (1000 mg) intravenously or daily, daily or several times a week, followed by switching to taking the drug Actovegin in tablet form. For diabetic polyneuropathy, administer 250 ml (2000 mg; 8 mg/ml) or 500 ml (2000 mg; 4 mg/ml) per day intravenously for 3 weeks, followed by switching to taking the drug Actovegin in tablet form - 2-3 3 tablets for at least 4-5 months. For wound healing, 250 ml (1000 mg) is administered intravenously daily or several times a week, depending on the speed of healing. Maybe joint use with Actovegin in dosage forms for external use. For the prevention and treatment of radiation damage to the skin and mucous membranes, an average of 250 ml (1000 mg) is administered intravenously the day before and daily during radiation therapy, as well as for 2 weeks after its completion, followed by a transition to taking the drug Actovegin in tablet form - 2-3 tablets 3 times a day for at least 4-5 months.
Tablet form: Prescribe 1-2 tablets orally 3 times a day before meals. Do not chew the tablet, wash it down with a small amount of water. The duration of treatment is 4-6 weeks. For diabetic polyneuropathy, Actovegin is administered intravenously at a dose of 2000 mg/day for 3 weeks, followed by switching to taking the drug in tablet form - 2-3 tablets 3 times a day for at least 4-5 months.
External use: For ulcerative lesions, pre-treatment for the purpose of cleansing them is carried out using a gel, which is applied in a thick layer and covered with a compress with 5% Actovegin ointment or a gauze bandage soaked in ointment. The dressing is changed once a day, for very weeping ulcers - several times a day. IN further treatment You should continue with Actovegin in the form of a 5% cream and complete treatment with Actovegin in the form of a 5% ointment, which is applied in a thin layer. After initial therapy with Actovegin in the form of a 20% gel, the cream is applied in a thin layer. To prevent bedsores, 5% cream or 5% ointment is rubbed into the skin in areas increased risk development of bedsores. To prevent radiation injuries, 5% cream or 5% ointment is applied in a thin layer immediately after radiation therapy and in the intervals between sessions.

Side effect: Allergic reactions: skin rash, skin hyperemia, hyperthermia, up to anaphylactic shock.

Contraindications to the use of the drug Actovegin: decompensated heart failure; pulmonary edema; oliguria; anuria; fluid retention in the body; increased sensitivity to the components of the drug; increased sensitivity to similar drugs. The drug should be prescribed with caution for hyperchloremia and hypernatremia.

Use of the drug Actovegin during pregnancy and breastfeeding: The use of the drug during pregnancy did not have any effect negative impact on the mother or fetus, however, if it is necessary to use the drug during pregnancy, the potential risk to the fetus should be taken into account.

Use for renal impairment: The drug should be prescribed with caution for oliguria and anuria.

Special instructions: Due to the potential development anaphylactic reactions It is recommended to carry out a test (test injection of 2 ml IM) before starting the infusion. In the case of intramuscular administration, the drug should be administered slowly in an amount of no more than 5 ml. Actovegin solutions have a slightly yellowish tint. The color intensity may vary from one batch to another depending on the characteristics of the starting materials used, but this does not affect the effectiveness and tolerability of the drug. Do not use a solution that is opaque or contains particles. After opening the ampoule or bottle, the solution cannot be stored.

Overdose: Information on overdose of the drug Actovegin is not provided.

Drug interactions: Drug interactions with Actovegin have not been established. However, in order to avoid possible pharmaceutical incompatibility, it is not recommended to add other drugs to the Actovegin infusion solution.

Conditions for dispensing from pharmacies: The drug is available with a prescription.

Storage conditions and periods: The drug should be stored in a place protected from light, out of reach of children, at a temperature not exceeding 25°C. Shelf life - 5 years.

An analogue of the drug Actovegin is the drug Solcoseryl (Solcoseryl) - a drug that activates metabolism in tissues, improves trophism and stimulates the regeneration process.

Active substance: deproteinized dialysate from the blood of healthy young calves. Release form: gel 20g in tube; ointment 20g in a tube; eye gel 5g in tube; solution for injection 42.5 mg/ml-2ml in ampoules No. 25; solution for injection 42.5 mg/ml-5 ml in ampoules No. 5; dental adhesive paste 5g.
The drug solcoseryl improves the transport of oxygen and glucose to cells under hypoxic conditions; increases the synthesis of intracellular ATP and promotes an increase in the dose of aerobic glycolysis and oxidative phosphorylation; activates reparative and regenerative processes in tissues; stimulates the proliferation of fibroblasts and the synthesis of collagen in the vascular wall.

Actovegin is a natural preparation; the basis for the medicine is an extract from the blood of calves. Actovegin is successfully used in various areas of medicine: cardiology, neurology, psychiatry, dermatology. The drug received approval in perinatal medicine. Exact analogues of Actovegin, except for Solcoseryl, practically do not exist. For this reason, patients buy generics or synonyms.

Application of Actovegin

The scope of the medicine is quite wide:

• The medicine increases the speed of metabolic processes at the cellular level.
• Improves the quality of blood microcirculation.
• Has antioxidant properties.
• IN short time heals tissue damage.
• Strengthens cellular resistance to oxygen deficiency.

The drug is used for impaired cerebral circulation, in the post-stroke period with a decrease in vascular tone, with complications after operations, for the treatment of encephalitis. Actovegin gels, creams, ointments help with skin damage, dermatological diseases, and burns. The medicine is used to treat pregnant women, since neither the mother nor intrauterine child it cannot harm.

In pediatrics, the drug is used to treat neurological diseases.

Contraindications to treatment with the drug:

• Acute forms pulmonary pathologies.
• Cardiovascular diseases.
• Kidney failure.

Analogues of the drug

The question of what to replace Actovegin with, and whether it can be done, worries many patients. Instead of Actovegin, medications with similar therapeutic effects are used. They have other names: analogues, generics. Cheap analogues of Actovegin are replaced by bakeries as prescribed by a specialist.

Solcoseryl at the same medicinal properties has a wider scope of application and is prescribed for the following pathologies:

• Stroke.
• Venous insufficiency V chronic form.
• Post-traumatic state after traumatic brain injury.
• Pathologies of peripheral arteries according to Fontaine.

The slight difference in the compositions of two similar drugs does not prevent the use of Solcoseryl as a full-fledged analogue of Actovegin

Cerebrolysin

The drug is of animal origin. The active ingredient of the drug is an extract from the brain of pigs. Actovegin substitute has a wide spectrum of action. The drug is used for the treatment of adults and children. Treatment with the drug is indicated for the manifestation of childhood hyperactivity, decreased intelligence in old age, depression, dementia syndromes.

Side effects medications:

• Sweating.
• Disruption of the gastrointestinal tract.
• Deterioration of sleep, irritability.
• Cramps.
• Painful sensations in the back and limbs.
• Dyspnea.
• Skin irritation.
• Apathy.

It is known that Cerebrolysin has been discontinued in many countries. In domestic medicine, the drug is successfully used for injection to restore the functional activity of the brain. The medicine does not have a tablet form; an analogue of Actovegin is used in ampoules.

Cortexin

Compared to Actovegin, Cortexin can be bought cheaper. The medicine is available in powder form. Before the injection, the substance is diluted with novocaine. Due to its mild effect, the medicine is recommended for children. The drug is prohibited for use by pregnant and nursing mothers. The medicine is a nootropic antioxidant. The active substance is extracted from the brain of pigs.

The most common use of the drug is in the field of pediatric neurology. The medicine is used for pathologies:

• Cranial injuries.
• Encephalitis.
• Developmental delay in childhood.
• Learning delay.
• Sleep disturbance.
• Memory loss.
• Post-stress conditions.
• For alcohol poisoning.

The drug has more indications than Actovegin. The medication is used in psychiatry, as a replacement for Actovegin, for brain toxicosis, pathologies of a neurotic nature, for the treatment alcohol addiction. Actovegin injections are prescribed in the presence of symptoms: anxious sleep, memory loss, post-stress conditions, intoxication as a result of alcohol poisoning.

Antioxidant, existing in 2 types: injection solution and tablets

Chimes

Helps improve microcirculation of the vascular system. Prevents hypoxia, eliminates platelet aggregation, helps reduce blood pressure. Used as an antiviral medicine. The drug treats heart pathologies, atherosclerosis, brain pathologies in the presence of weakened blood circulation. The medicine is also used to increase the body's defenses.

Semax

The medicine is released in the form of nasal drops. Used to treat damaged brain, to relieve mental stress in stressful situations. The drug is not recommended for use in pediatric practice.

Cavinton

The medicine has a price significantly lower than Actovegin. Cavinton is used for the treatment of auditory organs, as well as in ophthalmology. The Actovegin analogue in tablets is contraindicated for children. Also, pregnant women, nursing mothers, kidney pathologies, and heart disease should not take the medicine. If lactose intolerance exists, tablet treatment with Cavinton is not permitted.
Telektol, Vinpocetine.

These two drugs have similar effects because they have the same active ingredient. The medicine is prescribed if:

• pathologies of cerebral circulation,
• acute stroke,
• ischemia.

Omaron

Medicine includes 2 active substances: piracetam and cinnarizine. The drug is used for atherosclerosis, depression, and pathologies vestibular apparatus. Also an indication is a delay in the development of intelligence.

Ginkum

Natural remedy, which can replace Actovegin, restores memory, relieves stress, and helps eliminate tinnitus. The drug is used for cerebrovascular pathologies, in the post-stroke period, and for traumatic brain injuries.

The cheapest drug among Actovegin analogues. The medicine helps improve memory, central nervous system activity, and concentration. Unlike Actovegin, Piracetam does not change vascular microcirculation.

It is often recommended to use the medicine in complex therapy

Trental

Used for the treatment of lower extremities. Helps restore memory and sleep. Trental is effectively used for recovery in the post-infarction period. The medicine must not be used to treat patients under 18 years of age. The ban on treatment with the drug applies to pregnant and nursing mothers. It is important for the patient how much the medicine costs. But among analogues of Actovegin, you should buy, regardless of the price, a medicine prescribed by a doctor.

This article will present analogues of Actovegin.

This medicine is natural preparation affecting the metabolic processes of the body. The main active ingredient of the drug is a natural component that is obtained from an extract of calf blood purified from proteins.

Most often, this tool is used in the field of neurology, cardiology and psychiatry, as well as as an adjuvant in dermatology, ophthalmology and other medical fields.

Spectrum of action

The drug "Actovegin" 200 mg and analogues have a very wide range of effects:

• accelerates metabolism at the cellular level;
• improves blood circulation;
• has an antioxidant effect;
• accelerates the process of healing and tissue regeneration;
• eliminates complications after hypoxia and increases the resistance of body cells to oxygen starvation.

The drug "Actovegin" in the form of intramuscular injections and tablets is used for circulatory disorders in the brain, encephalopathy and some cognitive disorders, after traumatic brain injuries and surgical operations, as well as after strokes and with decreased vascular tone.

The gel and ointment of this drug are used for lesions skin, various dermatological diseases, burns and wounds. Analogues of Actovegin should be selected by a doctor.

Disadvantages and advantages of the drug

The main advantage is natural composition of this medicine. In the absence of contraindications, this medication can be used during pregnancy without harm to the mother and fetus. Most often it is used to treat a variety of neurological diseases in children. Natural composition This medication allows its use from the first days of a child’s life. In addition, a big plus is that the drug Actovegin combines well with some other medications.

Contraindications

Despite this, there are contraindications to the use of the drug Actovegin, but they are very few. These include:

• pulmonary edema;
• kidney diseases;
• heart failure;
• fluid retention.

In addition, this medicine should not be used if you are hypersensitive to the ingredients of the drug.

Adverse reactions

Although medicine"Actovegin" is quite easily tolerated, some problems may occur. side effects in the form of an increase temperature indicators and sweating, headaches, dizziness, disorders of the gastrointestinal tract, stomach pain, diarrhea, tachycardia, heart pain, urticaria, Quincke's edema.

If such reactions occur, you should stop using the drug "Actovegin" and replace it with another drug of similar effect.

In addition to side effects and contraindications, the cost can be considered a disadvantage of this medicine

Analogues of "Actovegin"

If necessary, the drug "Actovegin" can be replaced with medications that are equivalent in therapeutic effect. Such drugs are called “analogues” or “generics”. Despite the large number of analogues of this drug, which can be found in any pharmacy, replacement of the drug is necessary in mandatory agree with a specialist in order to avoid some complications and adverse reactions.

So, let's look at the most popular analogues of Actovegin.

Medicine "Solcoseryl"

This drug is the only one that coincides with the drug “Actovegin” in terms of active ingredients, one of which is an extract from the blood of calves. The drug is a tissue regeneration stimulator and is a chemically standardized dialysate that contains low molecular weight components of cell mass, as well as calf blood serum.

The drug increases resistance to hypoxia, activates cellular metabolism by enhancing the transport of glucose and oxygen, increasing intracellular utilization.

The healing effect of the drug "Solcoseryl" is manifested in increased re-epithelialization after chemical burns eyes, for example, with alkali, as well as after injuries and inflammatory processes.

The drug "Cerebrolysin"

This is an analogue of Actovegin in injections. This product is nootropic drug broad spectrum of action, which consists of peptides obtained from pig brain tissue. Used to treat people of any age. The drug has a pronounced multimodal organ-specific effect, i.e. it provides neuroprotection, metabolic regulation, neurotrophic activity and functional neuromodulation.

“Cerebrolysin” increases the efficiency of aerobic energy metabolism in the brain, normalizes protein synthesis in it, protects neurons from the harmful effects of lactic acidosis, prevents the formation of free radicals and the death of neurons under conditions of ischemia and hypoxia, and reduces the neurotoxic effect of amino acids. This medication is the only nootropic peptidergic agent with established neurotrophic activity, which is similar to the action natural factors neuronal growth, and, in addition, has a beneficial effect on the memory process in case of impaired cognitive functions.

This is confirmed by the instructions for use.

Analogs of Actovegin gel will also be presented.

Medicine "Cortexin"

This medication is a nootropic substance and contains low molecular weight water-soluble polypeptide fractions. It has a pronounced nootropic, antioxidant, neuroprotective and tissue-specific effect. Improves brain function, memory and learning, resistance to a variety of stress influences, improves concentration. The drug has an effect that protects neurons from damage by neurotoxic endogenous factors and reduces the toxic effect of the use of many psychotropic substances. The active components inhibit lipid oxidation, increase the survival of neurons under oxidative stress and hypoxia, activate metabolism, reparative processes improve the functions of the cerebral cortex and the tone of the nervous system.

Cheap analogues for Actovegin injections are easy to find.

Medicine "Mexidol"

It is an antioxidant drug that is used in psychiatry for toxic effects on the brain, neurotic disorders, to eliminate withdrawal symptoms. The medicine has membrane-protective, antihypoxic, nootropic, anxiolytic and anticonvulsant effects, increases resistance to stress and the body's resistance to damaging factors.

The medication improves metabolism and blood circulation in the brain, microcirculation and blood properties, reduces platelet aggregation, stabilizes the membranes of blood elements during hemolysis, has a pronounced lipid-lowering effect, reduces cholesterol levels and enzymatic toxemia in pancreatitis. The use of Actovegin analogues should be strictly according to the instructions.

Its mechanism of action

The mechanism of action of this medication is due to its antioxidant, antihypoxic and membrane protective effects. The drug inhibits the process of lipid oxidation and enhances the activity of superoxide dismutase. "Mexidol" modulates the activity of enzymes and receptor complexes, enhances their binding to ligands, promotes the structural and functionality of biological membranes, the transport of neurotransmitters, increases the level of dopamine in the brain, enhances the compensatory activity of aerobic glycolysis, normalizes the metabolic process in the ischemic myocardium, restores electrical activity myocardium, reduces areas of necrosis, increases coronary blood flow in areas of ischemia.

The drug also increases the activity of nitro drugs and favors the preservation of retinal cells and optic nerve for progressive neuropathies, the causes of which are hypoxia and chronic ischemia.

Cheap analogues for Actovegin injections can be purchased at any pharmacy.

Medicine "Semax"

The drug "Semax" is available in the form of nasal drops and is a synthetic peptide drug. The drug has an original principle of neurospecific action on nervous system and is considered a synthetic analogue of corticotropin, which has nootropic properties and lacks hormonal activity. This drug improves cognitive processes in the brain, increases mental activity, adaptation of brain cells to hypoxia, anesthesia and other damaging influences.

The drug is practically non-toxic both with single and long-term use. Allergic, teratogenic, embryotoxic and mutagenic reactions also do not occur during treatment with this drug. The drug does not have a local irritant effect.

We looked at cheap analogues of Actovegin in ampoules.

Comparison of drug analogues

All analogues of this medication differ in pharmacological categories and active ingredients. However, if you decide to replace Actovegin tablets with another drug, you need to pay attention to the fact that each of the analogues also has some additional areas of influence, which in some cases can cause certain side effects and allergic reactions.

Due to its identical composition, only the drug “Solcoseryl” is an absolute analogue of the drug “Actovegin”, therefore, when necessary, experts give preference to this particular medication. The Solcoseryl product has a shorter shelf life, and the Actovegin drug contains a special concentrate for long-term storage. This is their main difference. The cost of medicines is approximately the same.

The drug "Cerebrolysin", like "Actovegin", is also a medicine of animal origin. Both medications are widely used for neurological diseases, however, Cerebrolysin has a wider spectrum of effects and fewer contraindications. Their main difference is their ability to replace the functions of dead brain cells. The price of Cerebrolysin is slightly lower.

"Cortexin" differs from the drug "Actovegin" in that it has a milder effect on the body, however, the slower effect of its use also distinguishes it from this drug.

Mexidol also has a broader therapeutic focus and, unlike the drug Actovegin, not only affects blood circulation and metabolism, but also restores cognitive functions and improves memory. However, the drug Mexidol is contraindicated during pregnancy and lactation.

Pills

This form of release is represented by 3 generics of Actovegin:

• "Courantil";
• "Dipyridamole";
• "Vero-Trimetazidine".

The first two remedies are absolutely similar to each other. Both contain a myotropic vasodilator - dipyridamole. Thanks to this substance, blood microcirculation improves and platelet aggregation decreases, which promotes vasodilation.

An interesting property of “Curantil” and “Dipyridamole” is their effect on human immunity. When taking these medications, interferon production increases, as well as the body's protective qualities in the fight against viruses.

"Vero-Trimetazidine" is intended for the treatment vascular disorders, which were provoked by ischemia, usually in complex therapy. Active component The drug is trimetazidine, which normalizes energy cellular metabolism, ensuring the preservation of homeostasis during the transfer of potassium and calcium ions.

These are the main analogues of Actovegin in tablets.

Actovegin is a drug that significantly improves the number of metabolic processes in the body and has the ability to restore and regenerate new cells. The active ingredient is a specially isolated extract of demireate from the blood of young calves, completely free of protein.

The form of release of the drug is quite varied: in ampoules, in the form of a gel, ointment, cream, solution for injection and even in tablets. The average price in Russia is 1200–1600 rubles, depending on the form of release and the quantity of the medicine.

The main property of Actovegin is its rapid ability to restore blood circulation. The main indications for use are: presence of stroke, diabetes mellitus, arthritis various types, lupus and diseases caused by vascular disorders.

Price policy Actovegin is not small, so we should take a closer look at cheap analogues of the drug in Russia. You can also find a drug substitute produced in countries such as Ukraine and Belarus.

Russian-made analogues

Name of the drug	Price in rubles	Characteristic
Cortexin	800–1200	The active substance is a water-soluble compound of the polypeptide type. Due to ultra-high permeability, it quickly enters cells and significantly restores functional features brain. It is an effective analogue of Actovegin. It has contraindications in case of individual intolerance to cortexin; it is prohibited during pregnancy and lactation.
Vero – trimetazidine	90–120	It has a high antihypoxic effect and is not inferior to Actovegin in many characteristics. Widely applicable in ischemic strokes, cardiac hypoxia. Contraindicated in allergic reactions on the active substance, as well as during pregnancy and lactation.
Noben	500–600	Active substance Idebenone has the ability to increase oxygen volumes, improve blood circulation, and restore brain function. Prescribed for various types of neurasthenia, memory and attention disorders. Use is not recommended in case of intolerance to idebenone or renal failure.
Divaza	250–400	Performs a protective function of neurons, thereby favorably influencing the restoration of brain cells. The active ingredients of the drug are antibodies of a specific brain protein. In case of overdose, allergic side effects are possible. Use by pregnant women and children under 18 years of age is contraindicated.
Mexidol	250–500	A relatively inexpensive domestic analogue of Actovegin. The main substance, Mexidol, has an antioxidant effect and suppresses the development of hypoxia. It can be used in injections when administering an injection solution, dosed tablets. Contraindicated in high sensitivity to the components of the drug, acute renal failure, pregnancy, lactation.
Omaron	100–300	It has the ability to quickly dilate blood vessels, a neotropical effect. Active ingredients: piracetam, cinnarizine. Release form: tablets. Contraindicated in children under 5 years of age, pregnant women, and during lactation.

Ukrainian substitutes

There are many analogues of Actovegin produced in Ukraine.

The main ones:

1. Bioglobin - U. Stimulates the metabolic processes of the body, the main substance is bioglobin. Used by injection to treat various forms of arthritis.

   It is partially an analogue of Actovegin, but before use it requires the recommendation of the attending physician.

   Contraindicated for acute diseases hearts, oncological diseases on last stage, pregnancy, lactation. The average price is 300–500 rubles.

2. Ginkgoba. Dietary supplement, which helps improve brain function. The main substance is extract of the ginkgo biloba plant. Significantly improves memory, concentration, mental work.

   Has contraindications for high sensitivity. The average price is 120–220 rubles.

3. Cerebrovital. Also used as food additives to renew brain cells and improve the functioning of the cardiovascular system. The active ingredient is based on gotu kola and lecithin extract.

   If the drug is particularly sensitive, use during pregnancy and lactation is contraindicated. Medicine release form: tablets. The average price is 100–200 rubles.

4. Memorin. Release form: oral solution. Provides oxygen supply to the brain, improves metabolic processes.

   It is a relative analogue of Actovegin and is prescribed for circulatory disorders. The average price is 100–180 rubles.

5. Neuromin - brain energy. Biologically active additive containing a combination of natural components aimed at restoring and preventing the development of brain hypoxia.

   It has contraindications in case of high sensitivity to the components of the drug; it is not recommended for children under 6 years of age during pregnancy or lactation. The average price is 100–200 rubles.

Belarusian generics

Name of the drug	Price in rubles	Characteristic
Neurotropin	1000–1400	Active ingredient Mexidol. Restores oxygen supply to cells, improves blood circulation. Is high-quality analogue Actovegina. Prescribed for various hypoxia, encephalopathy, complex purulent processes (peritonitis).
Pyracesin	150–300	Active ingredients: piracetam, cinnarizine. It has an antihypoxic, vasodilating effect. Inexpensive analogue Actovegina. It is used not only for disorders of the brain, but also as a development stimulator for children with lagging abilities. Contraindicated in pregnancy, breastfeeding, renal failure, hypersensitivity to components.
Piracetam	50–100	Available prototype of Actovegin. The active ingredient piracetam has a positive effect on work brain activity practically does not cause side effects.

Other foreign analogues

A wide range of analogues of foreign production allows you to choose the highest quality and inexpensive synonyms of Actovegin.

1. Solcoseryl. The advantage of this drug is its almost complete identity with Actovegin. The active substance is also a dialysate purified from protein, obtained from the blood of young calves.

   Available in the form of a gel and solution for injection. Used to treat diseases caused by a lack of oxygen in cells and during the healing of wounds and burns. It is not advisable to take the medicine during pregnancy and lactation. The average price is 250–800 rubles.

2. Curantil 25. Contains the main substance dipyridamole. Prescribed for the treatment of various types of thrombosis, applicable for recovery after myocardial infarction. Suitable as an analogue of Actovegin.

   Release form: injections, tablets, dragees. Strictly contraindicated for acute course heart disease, arterial hypotension, stomach ulcers, liver and kidney dysfunction, high sensitivity to the drug, pregnancy and lactation.

   The average price is 600–900 rubles.

3. Nootropil. The main active ingredient is piracetam. A high-quality synonym for Actovegin. Available in the form of injections for injections, tablets, syrup for children.

   Effectively restores and improves brain function. Used to treat various pathologies of the nervous system.

   Main contraindications: pregnancy, lactation, liver failure, bleeding, special sensitivity to piracetam. The average price is 250–350 rubles.

4. Tanakan. Herbal preparation based on ginkgo leaf extract. Enough effective analogue, which improves blood circulation in the brain. Suitable for various neuroses, encephalopathy, Alzheimer's disease.
5. Anantavati. Regulates the activity of the brain using herbal medicines. Available in tablet form.

   Doesn't have serious contraindications, not recommended during pregnancy, lactation and children under 18 years of age. The average price is 100–250 rubles. Has positive reviews from a large number of people.

In the final part of the article I would like to summarize and say that it is better to choose cheap analogue Actovegin is not particularly difficult.

But it should be remembered that replacing with cheap drug should only be carried out on the recommendation of a doctor! After all, the health of any person is the main factor in his well-being. Be healthy!