Surely many people in home medicine cabinet there is Citramon. This drug is the development of Soviet pharmacologists. If, while abroad, a person asks for Citramon, they simply will not understand him. After all, this medicine is registered only in post-Soviet countries. What does Citramon tablets help with and how to take it correctly?
Composition of Citramon
Citramon is produced by many domestic pharmaceutical companies. This is a combination drug from the group, which consists of several medicinal components. The original composition of Citramon included the substance phenacetin, but due to its high toxicity they stopped adding it to the drug altogether. Classic Citramon consists of three components:
- at a concentration of 180 mg;
- - 240 mg;
- Caffeine - 30 mg.
Paracetamol has antipyretic, analgesic and, to a lesser extent, anti-inflammatory effects. Paracetamol is recognized throughout the world as one of the safest and most effective antipyretic drugs.
Acetylsalicylic acid also has analgesic, antipyretic (antipyretic) and anti-inflammatory effects. Besides, medicinal substance reduces platelet aggregation (sticking together), thereby preventing thrombus formation.
Caffeine improves blood circulation in tissues, reduces drowsiness, and significantly increases performance b. The dosage of caffeine in Citramon is quite small, and therefore it does not have a stimulating effect on the central nervous system. But the substance normalizes the tone of blood vessels in the brain, and also accelerates blood flow. All three components harmoniously enhance each other's action.
Various pharmaceutical companies also produce all sorts of variations of Citramon. As a rule, these variations differ in the concentration of active substances:
- The composition of Citramon Extra includes paracetamol 500 mg, as well as caffeine 50 mg;
- The composition of Citramon Forte includes paracetamol at a concentration of 240 mg, caffeine 40 mg, acetylsalicylic acid 320 mg;
- The composition of Citramon plus (Citrapak) includes paracetamol at a concentration of 180 mg, caffeine 30 mg, acetylsalicylic acid 240 mg, and 40 mg.
Note! On pharmacy shelves you can also find Citramon-P, this is the most ordinary Citramon.
Indications for use
Citramon is available in tablets. The main indication for its use is mild or moderate pain of any origin. So, Citramon helps with, arthralgia,. Citramon is also taken as an antipyretic (antipyretic) for diseases accompanied by high fever, for example.
The medicine is prescribed to adults, one tablet two to three times a day after meals. A maximum of six tablets per day (in three doses) is allowed; any larger quantity will cause an overdose. The drug must be taken with a sufficient amount of water. According to the instructions, Citramon can be taken as an antipyretic drug for no more than three days, and as a pain reliever - no more than five.
Side effects
In general, Citramon is well tolerated by patients. However, it is worth considering the possible side effects of the drug. Citramon contains acetylsalicylic acid, which can lead to the formation of ulcers on the mucous membranes of the stomach and intestines, and ulcerative bleeding.
Due to its antiplatelet effect acetylsalicylic acid the risk of internal, gingival bleeding may increase. Considering this, it is not recommended to use medications containing acetylsalicylic acid on the eve of surgical interventions or dental procedures.
In addition, it is known that the use of acetylsalicylic acid in children as an antipyretic drug for acute viral infections may lead to the development of Reye's syndrome. This pathological condition, manifested by rapid damage to the brain and liver. Reye's syndrome is characterized by high mortality. That's why Children should not take Citramon.
It is also possible that such side effects such as anxiety, irritability, headaches, dizziness, ringing in the ears (), rapid heartbeat, allergic reactions. Many people are interested in whether Citramon can raise blood pressure, because it contains caffeine. Among the side effects indicated in the instructions are: Caffeine is contained in Citramon in low concentration, and therefore does not cause pronounced increases in blood pressure. But at the same time, people with high pressure you need to be careful with Citramon.
Contraindications
Citramon is a very popular drug. But few people think about in what cases it should not be taken. Contraindications include:
- Hypersensitivity to the components of the drug;
- Blood diseases (leukopenia, );
- Exacerbation;
- Hepatic, ;
- Severe form expressed
Composition per tablet
Active substances
: acetylsalicylic acid - 240 mg, paracetamol - 180 mg, caffeine monohydrate or caffeine (caffeine anhydrous) - 30 mg.Excipients
: cocoa - 14 mg, lemon acid- 5 mg, potato starch - 63 mg, low molecular weight povidone (low molecular weight medical polyvinylpyrrolidone) - 4 mg, talc - 9 mg, calcium stearate - 5 mg. Description:tablets are light brown with inclusions, flat-cylindrical with a chamfer and a score, with the smell of cocoa.
Pharmacotherapeutic group:analgesic agent (analgesic non-narcotic drug + psychostimulant drug + non-steroidal anti-inflammatory drug). ATX:N.02.B.A.51 Acetylsalicylic acid in combination with other drugs, excluding psycholeptics
Pharmacodynamics:Combined drug.
Acetylsalicylic acid has an antipyretic and anti-inflammatory effect, relieves pain, especially caused by the inflammatory process, and also moderately inhibits platelet aggregation and thrombus formation, improves microcirculation at the site of inflammation.
Caffeine increases reflex excitability spinal cord, stimulates the respiratory and vasomotor centers, expands blood vessels skeletal muscles, head
brain, heart, kidneys, reduces platelet aggregation; reduces drowsiness, feeling of fatigue. In this combination, in a small dose, it has virtually no stimulating effect on the central nervous system, but helps regulate cerebral vascular tone.Paracetamol has an analgesic, antipyretic and weak anti-inflammatory effect, which is associated with its effect on the thermoregulation center in the hypothalamus and a weakly expressed ability to inhibit the synthesis of prostaglandins
(Pg) in peripheral tissues. Pharmacokinetics: Indications:Pain syndrome of mild and moderate severity (of various origins): headache, migraine, toothache, neuralgia, myalgia, arthralgia, algodismenorrhea. Feverish syndrome: for acute respiratory infections (ARI), influenza.
Contraindications:■ Peptic ulcer of the stomach and duodenum in the acute phase;
■ Gastrointestinal bleeding (including a history);
■ Severe liver and/or kidney dysfunction, gout;
■ Hemorrhagic diathesis, hypocoagulation;
■ Surgical interventions accompanied by heavy bleeding;
■ Pregnancy (I and III trimester), lactation period;
■ Glucose-6-phosphate dehydrogenase deficiency;
■ Glaucoma;
■ Hypersensitivity to the components of the drug, asthma induced by taking acetylsalicylic acid, salicylates and other non-steroidal anti-inflammatory drugs;
■ Children's age (up to 15 years - the risk of developing Reye's syndrome in children with hyperthermia due to viral diseases);
■ Increased excitability, sleep disturbances;
■ Organic diseases of cardio-vascular system(including acute myocardial infarction, atherosclerosis);
■ Severe arterial hypertension
■ Portal hypertension
■ Vitamin deficiency K
■ Hyioproteinemia
Carefully:■ Mild to moderate renal failure, liver failure with increased transamipase levels, benign hyperbilirubinemia (including Gilbert's syndrome, alcoholic liver damage), alcoholism, epilepsy and a tendency to seizures, elderly age, gout, arterial hypertension.
Pregnancy and lactation:Acetylsalicylic acid, when used in the first trimester of pregnancy, has a teratogenic effect; in the third trimester leads to inhibition labor activity. They are excreted in breast milk, so use during lactation is contraindicated. Directions for use and dosage:The drug should not be taken for more than 5 days as an analgesic drug and for more than 3 days as an antipyretic (without prescription and medical supervision).
Orally (during or after meals), 1 tablet every 4 hours, for pain - 1 - 2 tablets; the average daily dose is 3 - 4 tablets, the maximum daily dose is 8 tablets. The course of treatment is no more than 3-5 days.
Side effects:Adverse reactions characteristic of acetylsalicylic acid, paracetamol and caffeine may be observed: anorexia, nausea, vomiting, gastralgia, decreased platelet aggregation, erosive and ulcerative lesions of the gastrointestinal tract and duodenum, gastrointestinal bleeding, allergic reactions, bronchospasm, exudative erythema multiforme (including Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), renal failure, liver failure, dizziness, tachycardia, increased blood pressure. With long-term use - headache, blurred vision, tinnitus, hypocoagulation, hemorrhagic syndrome (nose bleed, bleeding gums, purpura, etc.), kidney damage with papillary necrosis, Reine's syndrome in children.
Overdose:Symptoms:
- for mild intoxications: nausea, vomiting, stomach pain, dizziness, ringing in the ears;
- in case of severe intoxication: lethargy, drowsiness, collapse, convulsions,difficulty breathing, anuria, bleeding.
Treatment:gastric lavage using activated carbon, symptomatic therapy, depending on the metabolic state - the introduction of sodium bicarbonate, sodium citrate or sodium lactate, which enhances the excretion of acetylsalicylic acid due to alkalinization of urine.
Interaction:Strengthens the effect of heparin, indirect anticoagulants, reserpine, steroid hormones and hypoglycemic drugs.
Concomitant use with other non-steroidal anti-inflammatory drugs and methotrexate increases the risk of side effects.
Reduces the effectiveness of pyrone o lactona, furosemide, antihypertensive drugs, as well as pros-gout drugs that promote the excretion of uric acid.
Barbiturates, . , antiepileptic drugs and other stimulants of microsomal oxidation promote the formation of toxic paracetamol metabolites that affect liver function.
Metoclopramide accelerates the absorption of paracetamol.
Under the influence of paracetamol, the elimination time of chloramphenicol increases 5 times. At readmission may enhance the effect of anticoagulin (dicoumarin derivatives). accelerates the absorption of ergotamine.
When taking the drug and alcohol-containing liquids simultaneously, the risk of toxic damage liver.
Special instructions:Do not prescribe the drug to children under 15 years of age due to the high risk of Reis' syndrome. Reye's syndrome is manifested by prolonged vomiting, acute encephalopathy, and liver enlargement.
Citramon for headaches is a combination drug that belongs to the group of analgesics and antipyretics.
Citramon helps provide analgesic, anti-inflammatory and moderate antipyretic effects. The active components of the tablets mutually enhance therapeutic effect each other. The drug helps to cope with moderate headaches and light forms migraine. For the treatment of severe pain, a combination of Citramon with other groups of drugs may be required.
Medical indications
It has been proven that if you have a headache, there is no simpler, but faster and more effective medicine.
Citramon is indicated for people of all ages: it can be a young mother or an elderly person.
It is only important that the patient has no contraindications to taking this drug.
Actions, indications and contraindications are determined by chemical features medications.
The drug will help every patient to eliminate pain of varying intensity.
Only after a detailed examination, studying all the symptoms of headache, will the doctor prescribe the necessary safe dosages of the medication.
You can also consult a pharmacist at your pharmacy for advice on use.
What side effects may occur in children taking Citramon?
If the dosage of the drug was exceeded or the tablet was taken by a child less than 15 years old, the following side effects may occur:
- nausea, which may progress to vomiting;
- convulsions;
- headache;
- bleeding from the gums;
- change in vision for the worse;
- development of allergies, which are accompanied by swelling, itching or rashes;
- change in blood pressure;
- increased heart rate;
- frequent bleeding.
To avoid such side effects You should strictly follow the instructions and be sure to take into account the contraindications of Citramon.
Release, use, dosage
Mostly the medication is produced in tablet form, but there are granular forms of release to create a solution against pain.
An annotation for the medication is often not included, because Citramon for pain is produced in blister packs.
The medicine is whitish in color, sometimes brown spots are possible. The composition of the pain medication may vary slightly depending on the manufacturer.
Therefore, if you have a headache, each of the citramones can act with different strength and intensity.
Features of the medicine:
- Citramon P is contraindicated in children under 15 years of age, as it contains acetylsalicylic acid. This is a combination medicine that helps immediately after taking it. The medicine not only relieves pain, but also affects thermoregulation.
- Citramon Forte is used in children from 14 years of age. If your headache is severe, it is enough to take 2 tablets of the medicine. This dosage helps to cope with severe attacks of pain. The maximum daily dosage should not exceed 6 tablets. Some therapists allow up to 8 tablets.
- There is Citramon Darnitsa. This is a typical drug with no special features. Today it is the most popular form of medication, which is not recommended for children. Helps with every episode of headache.
Other releases of medicine for pain are no noticeably different, although the composition differs somewhat.
Before using any medicine, it is important to consult a specialist.
Self-medication can be dangerous, causing serious consequences.
How to take Citramon?
Before starting to take the tablets, you should carefully study the instructions for the drug and consult your doctor.
Unless the doctor has prescribed a different regimen, adults and patients over 15 years of age should take citramon for headaches, 1 tablet every 4 hours.
The permissible maximum must not be exceeded daily dose, which is 8 tablets.
The tablet is taken during or immediately after a meal, washed down with plenty of plain water.
- The drug should not be taken for more than 5 days to eliminate headaches.
- If, in addition to pain, there is an increase in temperature, the tablets are not recommended for use for more than 3 days.
If during this time the use of the medicine has not had the proper therapeutic effect, you should consult a doctor and reconsider the treatment regimen.
If the dosage recommended by the manufacturer or attending physician is not followed, there is a possibility of overdose: nausea, vomiting, difficulty breathing, drowsiness. If an overdose occurs, you should immediately seek qualified medical help.
Composition of the drug
Citramon is combination medicine. Includes 3 main components for a more effective impact on the root cause of pain:
- aspirin (the element quickly minimizes fever, relieves acute inflammation, increases blood microcirculation, relieves headaches);
- paracetamol (has a pronounced antipyretic effect, headaches under the influence of the substance are quickly minimized);
- caffeine (acts as a kind of amplifier of the action of the other two components of the drug, has a tonic effect, relieves sharp pain in the head).
Why might a person have a headache?
The cause of pain in the head may be a disease cervical region spine, brain damage, colds or simple fatigue. A symptom such as headache accompanies:
p, blockquote 3,0,0,0,0 ->
- Migraine attacks in women and attacks cluster pain in men.
- Osteochondrosis, myogelosis, spondylosis and other diseases of the cervical spine.
- Defeat nerve ganglia located on the head.
- Infectious diseases: meningitis, encephalitis.
- Hemorrhagic or ischemic stroke.
- Aneurysm rupture.
- Vascular spasm or chronic pathological narrowing of blood vessels.
- Diseases of the ENT organs: frontal sinusitis, sinusitis, sinusitis.
- Inflammatory processes affecting the ear: otitis media, Meniere's disease.
- Benign or malignant neoplasms in the brain.
Cold, food poisoning, withdrawal syndrome also occurs with headache. Discomfort may occur in people who have suffered a head or neck injury. It is not possible to drink Citramon from the head for every type of pathology; you should definitely follow the instructions and follow the doctor’s recommendations when choosing a medicine.
p, blockquote 4,0,0,0,0 ->
Action of the medication
The medicine works from the first minutes after use. We are talking about a non-steroidal medicine that overcomes headaches of mild to moderate intensity.
It has a mild antipyretic and anti-inflammatory effect on the body.
The tablets improve blood flow in the area where vascular headaches occur. This leads to rapid relief of symptoms.
The effect of the medicine is not only beneficial. The tablets also have a pronounced negative effect.
Due to the presence of aspirin, the medication has a negative effect on the gastric mucosa.
Frequent consumption of Citramon leads to the appearance of ulcers, decreased blood clotting, and allergic reactions.
Due to the presence of caffeine, the effect of the medication includes a sedative effect. At the same time, aspirin helps reduce the ability of platelets to stick together, which also helps prevent thrombosis.
Interaction of Citramon with other drugs
When using Citramon tablets, it is necessary to take into account possible drug interactions drug.
When used simultaneously with indirect anticoagulants, heparin, reserpine, steroid hormones and hypoglycemic drugs, Citramon may enhance the effects of these drugs.
Taking Citramon reduces the effectiveness of diuretics, medications for gout and high blood pressure.
When used simultaneously with barbiturates, antiepileptic drugs, rifampicin, the risk of negative effects on the liver increases.
If long-term use of the drug is necessary, therapy should be carried out under constant medical supervision. The patient must constantly monitor blood pressure levels, the condition of the liver and kidneys, and take blood and stool tests.
Mode of application
Before use, it is important to familiarize yourself with the features of treatment with Citramon. The medication is indicated for short courses of therapy to prevent the harmful effects of the components of the drug on the liver elements and nerve structures.
Citramon is successfully used not only for headaches, but also for episodes of dental, muscle, and joint pain.
The medicine does not help when it comes to chronic form pain or severe intensity of manifestations.
You should not take more than 8 Citramon tablets per day. Otherwise, severe poisoning develops, even death is possible.
The indications note the beneficial effect of the drug in initial stages viral infection, when there are chills, fever and body aches.
Thanks to its combined composition, Citramon is able to eliminate the primary manifestations of the disease.
Pregnancy, lactation - features of therapy
This drug is not recommended for use during pregnancy. The danger of such therapy is associated with aspirin, which is part of Citramon.
This element can adversely affect the baby, provoke bleeding, premature birth and weakness of labor.
You should not take the medicine during lactation. Its components easily pass into milk, and therefore affect the development and growth of the baby.
The greatest danger is the bleeding that may appear in a child after such feeding.
Contraindications
Tablets cannot be taken in case of intolerance to the active or auxiliary substances of the drug, with aspirin asthma, as well as with:
- Gastric ulcer (exacerbation phase of the disease) and gastric bleeding;
- Vitamin deficiency K;
- Increased blood pressure;
- Serious kidney problems;
- Coronary heart disease (severe form);
- Glaucoma;
- At nervous diseases which are accompanied by excitability and insomnia;
- In the period after surgical interventions accompanied by the development of bleeding.
Citramon is used with extreme caution in the development of gout and liver diseases.
Advantages and disadvantages
Almost everyone can take the medicine. It's cheap and effective remedy against headaches. You can take the drug to normalize blood flow.
Due to the caffeine, the drug is used as a sedative. You need to drink Citramon, adhering to the prescribed dosage.
In this case, the medication stimulates the nervous system and brain productivity. You can drink it to stabilize blood flow and normalize blood pressure.
He owns next negative qualities. Long-term drug therapy always leads to the formation of ulcers in the stomach.
In some cases, allergic manifestations and increased bleeding are possible.
Side effects
Taking the drug Citramon may contribute to the development of such adverse reactions: allergies, nasal congestion, rhinitis, itching, bleeding gums, skin rash, dyspeptic disorders, nausea, discomfort and abdominal pain, inflammatory process in the gastrointestinal tract, hypoglycemia, vomiting.
In some cases, sleep disturbances, feelings of fear and anxiety, ringing in the ears, tachycardia, hypoglycemia, and visual impairment were reported.
If these or any other adverse reactions develop, it is recommended to stop using Citramon and consult a doctor. In the future, you may need to reduce the dose of the medicine or find a replacement.
What is better aspirin or paracetamol
Paracetamol – effective medicine to relieve headaches and stabilize temperature. The main advantage of paracetamol is practically complete absence contraindications, resulting in drug approved for use even in infants.
Medication dosage:
- for adults and children over 12 years old – 500 mg up to 4 times a day;
- for infants aged 3 months to 1 year – 60-120 mg single dosage;
- for children 1-5 years old – 120-250 mg;
- for children 6-12 years old – 250-500 mg.
Infants up to 3 months can be given 10 mg per 1 kg of weight up to 4 times a day at intervals of 4 hours.
Paracetamol crosses the placenta, but no negative effects on the fetus have been detected. The drug should be taken with caution during pregnancy and only on the recommendation of a doctor. During lactation, it is necessary to temporarily stop breastfeeding when using the product.
Citramon: instructions for use, contraindications
The drug can cope with mild, moderate and severe pain. The main indication for the use of this drug is headache. Citramon treats pain resulting from:
- migraine;
- vascular spasms;
- neck muscle tension;
- neurological spasms;
- influenza and other viral infections.
The analgesic effect when taking Citramon during a migraine is achieved thanks to caffeine, which has a positive effect on the condition of the blood vessels in the brain and makes blood flow faster.
However, the combination of components that relieve spasms and inflammation allows the drug to be used for other types of pain. What does Citramon P help with? The medicine is taken to eliminate:
- toothache;
- pain during menstruation;
- muscle pain;
- febrile conditions during influenza or ARVI;
- joint pain.
Patients often have a question about how to take Citramon in order not only to get rid of headaches, but also not to harm their health. Citramon for headaches should be taken in short courses, taking no more than one tablet three times a day after meals. If you have a severe headache, the dosage can be increased, but it is strictly forbidden to take more than 8 tablets in one day, as this can cause severe Citramon poisoning.
Citramon will relieve headaches that are accompanied by high body temperature due to viral infections and acute respiratory infections, but in this case it is forbidden to drink it for more than three days.
Like any other medicine, Citramon P has a number of contraindications:
- Allergic reactions to the components of the drug.
- Diseases of the stomach and intestines, especially gastritis and ulcers. Taking Citramon in this case can provoke internal bleeding in the stomach.
- Kidney and liver diseases.
- Sleep problems and increased excitability of the central nervous system.
- Glaucoma.
- Pregnancy and lactation. The drug can cause abnormalities in fetal development.
- Heart failure.
- Bronchial asthma.
- Age up to 15 years.
Since the drug contains caffeine, many experts do not recommend taking it to patients suffering from arterial hypertension, because this component can cause an increase in blood pressure. However, hypertension can only be considered a relative contraindication to taking Citramon, because the concentration of caffeine in the medicine does not exceed 3 g.
Side effects may occur while taking Citramon:
- bleeding due to poor blood clotting;
- changes in blood pressure;
- tachycardia;
- dizziness and increased pain in the head;
- nausea, and in some cases vomiting;
- kidney dysfunction;
- the appearance of rash and itching on the mucous membranes and skin;
- tinnitus, partial loss of vision.
Since the drug has quite a few contraindications, it is better to consult a specialist before taking it.
- Toothache. This is a temporary solution until you go to the dentist, because sometimes tooth pain can become so unbearable that it interferes with the normal functioning of the body.
- Headache. The drug is recommended for low blood pressure, since the caffeine it contains will increase it, and if the cause of the pain was high blood pressure, then your head will start to hurt even more.
- Muscle pain. It is better to combine the medication with a neck or head massage to relieve tension.
- Menstrual pain. The drug will not save you from them completely, but will help relieve spasms and relieve general state body.
- A cold that causes pain and tension in the muscles.
- Infectious diseases. In this case, it is better to discuss taking the drug with your doctor.
- Joint pain. Citramon will be a temporary solution for eliminating joint pain, since full treatment will require a whole range of drugs and measures.
It is believed that Citramon for headaches is a universal remedy, easy to use, but even it has a number of contraindications, in the presence of which the medicine will not only not help, but will also harm.
Contraindications:
- Allergic reactions to the active or auxiliary substances of the drug.
- Exacerbation of gastrointestinal ulcers. Even small doses of the drug have an aggressive effect on the mucous membrane and can worsen the patient’s condition and develop the risk of bleeding.
- Gastrointestinal bleeding. The main sign of bleeding is blood in the stool.
- Hemophilia and other diseases of reduced blood clotting. Citramon has a certain effect on human blood, which in the presence of these diseases can lead to complications and even bleeding.
- Hemorrhagic diathesis. In these cases, the walls of the vessel become thinner and the risk of bleeding increases.
- Increased pressure in portal vein due to deterioration of blood circulation in adjacent portal vessels. This often indicates liver disease.
- Lack of vitamin K in the body. This also leads to an increased risk of bleeding.
- Kidney failure. Citramon causes a lot of stress on the kidneys, so its use is contraindicated for any problems with this organ.
- Pregnancy. Citramon can have a destructive effect on the fetus and slow down the birth process.
- Lactation period. Various components of the drug enter the child’s body along with mother’s milk, which can negatively affect its development.
- High blood pressure. Citramon due to caffeine will increase this pressure even more.
- Cardiac ischemia.
- Increased intraocular pressure.
- Increased excitability. Caffeine will only make this condition worse.
- Sleep problems. Caffeine has an invigorating effect, which will only worsen insomnia.
- The period before and after surgery. Citramon increases the risk of bleeding.
- Childhood.
Citramon, like other drugs, has a number of contraindications for use. These include:
- Allergy to any of the components included in the tablets.
- Tendency to ulcers or inflammation of the gastrointestinal tract.
- Hemorrhagic diathesis.
- Ischemia.
- Bronchial asthma.
- Any chronic diseases.
- Acute heart failure.
- Vitamin A deficiency.
- Liver and kidney diseases.
- Hypertension.
- Hemophilia and other blood diseases.
- Nausea and vomiting.
- Inflammation of the gums.
- Changes in blood pressure.
- Blood clotting disorder.
- Heartbeat disturbance.
Since caffeine, which is present in Citramon, increases blood pressure, before taking another tablet, make sure that your blood pressure is within normal limits.
It is worth noting that taking Citramon is incompatible with drinking alcohol, as this can lead to bleeding in the intestines and increase the toxic effects of alcohol on the human body.
If the pressure is low, then the blood moves too slowly, and therefore it transfers more slowly. necessary for the body substances and oxygen. As a result: the body, as a rule, is cold, hungry, and a headache develops from lack of oxygen and vascular spasm.
If the pressure is high, then the blood moves unnaturally quickly, a large load is placed on the heart, the person becomes hot, there is tinnitus, pulsation in the temporal region. Excessive stress on blood vessels provokes headaches.
Blood pressure, as you know, has two indicators: systolic and diastolic. Systolic pressure is the pressure in the blood vessels that occurs when the heart contracts and pushes blood into the circulatory system. Diastolic pressure is a measure of the pressure at the moment when the heart relaxes after systole.
We’ll talk further about how citramon affects blood pressure.
Inexpensive but fast-acting Citramon is familiar to almost every woman. Not everyone uses it in everyday life, but many know that Citramon helps with various pains, fever and inflammatory processes. Most often, it is women who resort to its help, because it can improve the condition during menstrual bleeding, although it has a blood-thinning effect (that is, it can potentially cause bleeding), which not everyone thinks about.
And yet, the main difference between Citramon, for which people “loved” it, is its pronounced analgesic effect. This drug is quite quickly and almost always able to eliminate or reduce headaches, toothaches, and muscle pain, thanks to which it has received a reliable registration in our home medicine cabinets.
Phenpiverinium bromide (an antispasmodic), reducing the hypertonicity of smooth muscles, blocks pain and has a relaxing effect.
- allergic reactions or intolerance to its constituent components;
- stomach or duodenal ulcer;
- hypertension or high blood pressure;
- dysfunction or disease of the kidneys or liver;
- Citramon can cause health problems in the baby, so women during pregnancy and nursing mothers are prohibited from using it;
- increased excitability of the central nervous system, since the caffeine contained in the tablets can cause sleep disturbances.
With cardiac or renal failure reception is reduced to a minimum, and in some cases prohibited.
Regarding the question that interests many, whether Citramon-P can be taken by children, we can definitely say that under 15 years of age it is not recommended, as it can provoke brain disease (Reye's syndrome), as well as liver dysfunction. Side effects observed with overdose include nausea and vomiting, convulsions, rapid pulse, unstable arterial pressure, and in some cases – bleeding gums.
Moderate pain of the following origin: toothache, headache, muscle pain, spasms during menstruation, symptoms of fever during influenza, acute respiratory infections, as well as all other diseases one way or another associated with inflammation and infection.
Children, pregnancy and breastfeeding
Citramon is contraindicated in the first and third trimester of pregnancy. Acetylsalicylic acid, which is part of it, has a teratogenic effect, which can lead to the development congenital anomalies fetus
Use in the third trimester promotes premature closure of the aortic duct and increases the risk of bleeding during childbirth. In the second trimester, indications for Citramon should be carefully assessed by a doctor. The drug can be used only in cases where the expected benefit from the treatment significantly outweighs the potential risk of impact on fetal development.
The use of ASA-containing drugs for the treatment of ARVI in children (with or without hyperthermia) is contraindicated without prior consultation with a doctor.
For some viral infections (particularly infections caused by a virus chickenpox or influenza A or B viruses) there is a possibility of developing acute hepatic encephalopathy (Reye's syndrome), which requires immediate medical intervention. One of the signs of Reye's syndrome is prolonged vomiting.
Taking into account the above reasons, the use of tablets in patients under sixteen years of age is contraindicated. Since the drug has a large number of side effects, for children with a headache or toothache, it is better to choose safer remedies.
What is better analgin or aspirin
Analgin is another drug for effectively eliminating headaches. It is impossible to say which of these drugs is better; much depends on personal tolerance to the drug. However, analgin has a significant advantage - taking this medicine is allowed in childhood.
Analgin tablets contain the active component - metamizole sodium.
Dosage:
- adults – 250-500 mg 2-3 times a day;
- children aged 2 to 3 years – 50-100 mg;
- children aged 4-5 years – 100-200 mg;
- children 6-7 years old – 200 mg;
- children 8-14 years old - 250-300 mg.
The drug is used with caution during pregnancy and in children under 3 months.
Pregnant
During pregnancy, the use of citramon is possible only in the second trimester.
Vacation conditions and price
The average cost of Citramon P (tablets No. 10) in Moscow is 10 rubles. The pharmacy chain dispenses the medication without a doctor's prescription. It is recommended to consult a medical specialist before taking them.
The shelf life of Citramon tablets is 4 years. They must be stored in an intact package, in a dark, dry place, out of reach of children, at an air temperature of no higher than 25 C.
https://www.youtube.com/watch?v=Mmw7Q5lEG3M
Can citramon help with migraines?
Citramon is available in the form of tablets that are light brown in color and smell of caffeine. The main indication for its use is the treatment of headaches.
The drug contains several active substances, namely:
- Acetylsalicylic acid
- Paracetamol
- Caffeine
- Excipients.
Citramon refers to pharmacological group analgesics and antipyretics. Therefore, it has a wide range of applications.
But the main indication is the relief of migraine headaches. However, before starting treatment, it is necessary to establish a final diagnosis.
In the human body, Citramon exhibits the following effects:
- Reducing pain severity
- Stopping the inflammatory reaction
- Decreased body temperature
- Reducing the adhesion of red blood cells to each other.
In addition, this drug helps restore microcirculation in the inflammatory focus, which helps resolve inflammation. This effect is not known to everyone, so it is rarely used for anti-inflammatory purposes, although it turns out to be quite effective in this regard.
The effectiveness of the drug for migraines primarily depends on the caffeine included in the drug. This substance helps normalize tone cerebral vessels, and also accelerate intracerebral blood flow.
Doses used for migraines do not cause pathological agitation nervous system, That is important advantage this drug.
Analogues
Citramon has many both Russian and foreign analogues, expensive and cheap.
Askofen-P
- tablets, 10 pcs. – 27 rub.
- tablets, 20 pcs. – 51 rub.
Coficil-Plus
- tablets, 10 pcs. – 9 rub.
Migrenol Extra
- tablets, 8 pcs. – 196 rub.
- tablets, 16 pcs. – 233 rub.
Excedrin
- tablets, 10 pcs. – 159 rub.
- tablets, 20 pcs. – 260 rub.
How to get rid of a hangover
Massage and self-massage. To relieve tension pain, you can rub your neck, occipital part skulls
A compress is applied to the head, warm or cold, depending on what brings relief.
Walking on fresh air, frequent ventilation of sleeping areas. Water treatments– taking a relaxing bath, preparing a foot bath with mustard.
Help eliminate nerve pain medicinal decoctions from herbs: anise, motherwort, lingonberry, hawthorn, coltsfoot leaves, bearberry. You can prepare a decoction from one type of herb or a mixture of them.
Remember, you can rarely take pills for headaches, no more than once a month. If discomfort is noted frequently, the discomfort does not go away when taken medicines, you need to seek help from medical professionals.
Nursing mothers
Citramon does not affect lactation, but its use during breastfeeding is contraindicated.
The components of the drug are able to penetrate into breast milk, and with it - into the baby’s body. This increases the risk of developing Reye's syndrome in a child.
If taking citramone is necessary, you should:
- stop breastfeeding;
- reduce the dosage of the drug (down to 1/2 tablet);
- drink more fluids to quickly remove the drug from the body.
Characteristic
The active ingredient in Aspirin is acetylsalicylic acid. It has antipyretic and analgesic effects. It affects the central areas of the brain, eliminating pain and discomfort and lowering body temperature. This fast-acting remedy. So, the effect appears within 10 minutes after taking the tablet.
The tablets are coated with a special coating that dissolves in the intestines.
This is aimed at reducing the occurrence of peptic ulcers. The tablet also contains cellulose and corn starch, but they do not have any therapeutic effect.
Aspirin is produced only in tablet form. Intravenous and intramuscular injections this drug does not exist. You can only find analogues of Aspirin, presented as effervescent soluble tablets. Due to this, the action of the drug is accelerated and the effect occurs within a few minutes.
Range
Release forms
- pills;
- granules or powder for preparing a solution;
- capsules.
Choose a granular or powder analgesic: when dissolved, it will penetrate the bloodstream faster and exhibit pain-relieving properties.
Tablets are produced:
- 6 pieces in paper packaging;
- 10 and 20 in blister packs;
- 30 in polymer jars.
Brands and manufacturers
| Name | Manufacturer |
| Citramon-P | "Avexima", "Pharmstandard", "Uralbiopharm", "Tathimfarmpreparaty", "Reneval", "Atoll" |
| Citramon MFF | "MosPharma" |
| Aquacitramon | "Rozpharm" |
| Citramon-LekT | Tyumen Chemical and Pharmaceutical Plant |
| Citramon Borimed | Borisov Medical Preparations Plant |
| Citramarine | "Marbiopharm" |
| Excedrin | GlaxoSmithKline Healthcare |
| Citramon-P Ultra | "Atoll" |
| Citramon Ultra | Obolensk pharmaceutical enterprise |
| Citrapar | "Bryntsalov-A" |
| Migrenol Extra | Four Ventures Enterprises |
| Coficil Plus | "Uralbiopharm", Barnaul Medical Preparations Plant |
| Askofen-P | "OTCPharm" |
Price category
The popularity of Citramon to a certain extent may be due to its affordable price. Tablets in regular paper packaging will cost no more than 10 rubles. Citramon is available in almost every pharmacy different options, from 10 to 100 rubles per package. The price will ultimately be influenced by the manufacturer itself and how the medicine is packaged.
Citramon is one of the most affordable analgesics - its cost starts from 3-4 rubles for 10 tablets in regular packaging and ends at a price of just over 100 rubles for a concentrated drug in modern blisters. For the most part, the final price is influenced not so much by the composition as by the packaging, so the price of Citramon remains budget-friendly.
Citramon for headaches: features of the drug use
If symptoms have been bothering you for a long time, get tested. There is a suspicion of:
- Migraine is a chronic pathology that requires the use of potent triptans.
- Stroke or pre-stroke condition. It can be provoked by ischemia (vascular thrombosis), atherosclerosis, hemorrhage (internal bleeding) and accompanied by severe attacks of headache.
- Tumor - new growths in the brain require surgical intervention.
- Congenital aneurysms.
- Stress pain or muscle strain.
In the latter case, it is not necessary to immediately take Citramon or Analgin tablets. Rest helps deep sleep and relaxing massage. In general, you should remember: when a headache starts, you don’t need to take medications right away.
- acetylsalicylic acid: as a means of relieving inflammation, affecting heat exchange and blood permeability into capillaries. As a result, the feeling of pain is dulled;
- phenacetin: on this moment the product is withdrawn from production due to identified side effects;
- caffeine: as a central nervous system energizer, respiratory system, increasing the tone of the heart muscle, accelerating the pulse and heartbeat. In addition, after taking it, the desire to sleep and fatigue disappears, activity and performance increase;
- cocoa: as an organic antidepressant and stimulant;
- citric acid: as a catalyst for biochemical reactions in the body.
Content
Every first aid kit contains a universal drug that relieves fatigue, treats headaches or toothache, has an anti-inflammatory and antipyretic effect - Citramon P tablets. In order not to harm the body when taking the medication, doctors advise strictly adhering to the dosages indicated in the instructions, the course of administration and becoming familiar with the side effects.
What is Citramon P
This is a combined non-hormonal analgesic wide range actions. The drug has analgesic, antipyretic and anti-inflammatory effects. Tablets are prescribed by doctors to eliminate various pain syndromes, when the first symptoms of flu appear or when colds. The combined drug increases blood pressure in hypotensive patients, effectively eliminates toothache, and helps with elevated body temperature.
Compound
Early Citramon was produced on the basis of several active ingredients: acetylsalicylic acid, phenacetin, cocoa, caffeine and citric acid. However, after the official international ban on phenacetin classic recipe slightly modified. Now the composition includes acetylsalicylic acid, caffeine and paracetamol. Auxiliary components of Citramon P: potato starch, citric acid, talc, calcium stearate. Dosage active ingredients in one tablet is presented in the table:
Release form
Tablets of heterogeneous content with small inclusions, usually brown or light brown in color. The quantity and form of packaging depends on the manufacturer, for example:
- Citramon, produced by the Anzhero-Sudzhensky Chemical Plant, is produced in a cardboard pack, blisters of 20 pcs.
- Tablets from pharmaceutical company Tatkhimpharmaceuticals are sold in paper packaging of 6 pcs.
- Pharmstandard-medicines produce Citramon in aluminum blisters of 10 pcs.
Pharmacodynamics and pharmacokinetics
The effect of citramon is due to the influence of active components on the body:
- Acetylsalicylic acid has an antipyretic effect, has anti-inflammatory properties, relieves pain, reduces microcirculation at the site of inflammation and reduces platelet aggregation.
- Paracetamol has antipyretic and analgesic properties.
- Caffeine affects the reflex excitability of the spinal cord, respiratory centers, and dilates blood vessels. Caffeine enhances the effect of the previous components, affects the excitation center of the brain, and increases tone.
After taking the medicine active substances absorbed into the bloodstream through gastrointestinal tract. Under the influence of liver enzymes, they break down into metabolites. About 5% of paracetamol metabolites, 10% of caffeine and 60% of salicylates are excreted unchanged in the urine. The active ingredients are easily absorbed into peripheral tissues and body fluids. The maximum concentration in blood plasma is reached an hour after taking the tablet.
Citramon - indications for use
The drug is often used for muscle pain after severe physical activity, to eliminate depression, with low blood pressure. Citramon is often taken to treat fever and other manifestations of infectious viral diseases. According to the instructions, it is advisable to use the tablets:
- for pain syndrome of moderate and weak intensity - headache or toothache, migraines, myalgia, neuralgia, algodismenorrhea;
- for febrile syndrome - acute respiratory infections, acute respiratory viral infections, influenza, colds.
Citramon P - instructions for use
The tablets must be taken orally with a sufficient amount of liquid, immediately after meals. The medicine is taken 2-4 times a day, one tablet. The interval between doses should be at least four hours, and the average dosage should not exceed 3-4 tablets per day. For severe headaches, Citramon can be taken immediately in double dosage. The maximum upper limit of tablets in this case should not exceed 8 pieces. As an antipyretic, you can take the medicine for up to 3 days, as an analgesic - no more than 5 days.
special instructions
With long-term use of the drug, the patient must regularly undergo a blood test to count platelets, a stool test for hidden bleeding, check the condition of the liver and monitor blood pressure. It should be remembered that the medicine contains caffeine, so taking similar drugs with its participation can provoke an overdose.
Tablets can affect the results of doping control in athletes and complicate the diagnosis in the presence of the syndrome acute abdomen. The use of drugs based on acetylsalicylic acid is prohibited before surgical intervention or dental surgery, due to an increased risk of bleeding. Citramon affects the speed of thinking, so during treatment you should stop driving a vehicle and performing dangerous work.
During pregnancy
Use of the drug in the first trimester of pregnancy leads to cleft palate in the child, and in the third trimester to inhibition of labor and hyperplasia of the pulmonary vessels of the fetal pulmonary circulation. Citramon passes into breast milk. Its use during lactation can cause platelet dysfunction in the child and bleeding.
In childhood
According to the instructions, the drug can be used from the age of 15. In children younger age pills can provoke Reye's syndrome, cause serious damage central nervous system and liver dysfunction, suppress platelet synthesis and cause hemorrhagic diathesis. In addition, ASA negatively affects the gastric mucosa of children.
For impaired renal and liver function
Elderly patients and patients suffering from impaired renal and/or liver function, people with benign hyperbilirubinemia should be careful when taking the medicine. Long-term use of paracetamol-based tablets can lead to irreversible renal failure and cause drug-induced nephropathy.
Drug interactions
Citramon tablets must be combined correctly with other medications, otherwise complications and unforeseen situations may arise. Eg:
- the drug enhances the effect of heparin, reserpine, steroid hormones, indirect anticoagulants and hypoglycemic agents;
- simultaneous use of tablets with methotrexate or other non-steroidal anti-inflammatory drugs increases the risk of side effects;
- when interacting with furosemide, gout medications, antihypertensive tablets, their effectiveness decreases;
- rifampicin, barbiturates, anti-epileptic drugs and salicylamide provoke the release of toxic metabolites of paracetamol, which negatively affect the liver;
- when used simultaneously with metoclopramide, the absorption time of paracetamol is reduced;
- Citramon may enhance the effect of anticoagulants;
- taking paracetamol and ethanol increases the risk of hepatotoxic effects.
Side effects
As a rule, when taking Citramon according to the instructions or recommendations of a doctor, negative reactions of the body do not occur; the following rarely appears:
- anorexia;
- erosive and ulcerative lesions;
- nausea;
- bronchospasms;
- allergic reactions;
- gastralgia;
- epidermal necrolysis;
- exudative epithema;
- dizziness;
- gastrointestinal bleeding;
- increased blood pressure and tachycardia;
- noise in ears.
Overdose
If you use pills haphazardly, the following symptoms may occur:
- Mild intoxication – vomiting, nausea, tinnitus, dizziness, stomach pain.
- Severe degree of poisoning - drowsiness, collapse, convulsions, inhibition of reactions, bleeding, coma, anuria, difficulty breathing, respiratory acidosis. With further use of the medicine, irreversible liver damage and kidney dysfunction may occur.
Contraindications
The drug is not prescribed to children under 15 years of age and pregnant women. In addition, citramon is contraindicated:
- at hypersensitivity to the components of the drug;
- glaucoma;
- hemophilia;
- with gastrointestinal lesions;
- presence of bleeding;
- bronchial asthma;
- liver diseases;
- arterial hypertension;
- hypoprothrombinemia;
- increased excitability;
- sleep disorders;
- vitamin deficiency;
- before surgical operations.
Terms of sale and storage
The drug is dispensed from pharmacies without a doctor's prescription. Citramon must be stored in a dry place at a temperature not exceeding 25 degrees. The shelf life of the medicine is 2 years.
Analogues
Synonymous drugs with the same composition of active ingredients are:
- Aquacitramon;
- Migrenol Extra;
- Excedrin;
- Coficil-plus;
- Citrapar;
- Citramon-Darnitsa;
- Askofen P;
- Citrapak;
- Atsepar;
- Tomapirin P;
- Askofen plus;
- Aldon;
- Askofen-ANVI;
- Algomin;
- Neuranidal;
- Iralgesik.
Price for Citramon P
You can purchase the drug at any pharmacy in the country at an affordable price or order home delivery of medications through the online store. The approximate cost of the tablets is shown in the table below:
Video
Citramon is available in almost every home - it is inexpensive, in many ways universal medicine, which helps with headaches, fever, low blood pressure, toothache and hangover. The medicine does not contain narcotic substances or hormones, gives a good general analgesic effect and can eliminate almost any unexpressed pain symptoms, regardless of the type of disease and level of its development.
Citramon is produced by Russian and foreign enterprises. In this case, the medicine has approximately the same composition. Previously, Citramon contained phenacetin, but it has long been considered toxic, so it is not added to modern medicines.
Also now in many pharmacy chains you can find Citramon Ultra, which is an analgesic and antipyretic agent with a varied combined composition. Citramon Forte is also on sale - this is a combination medicine that reduces fever, calms inflammatory processes, and provides good pain relief.
Before talking about what Citramon helps a person with, you need to list in detail the main components:
- Acetylsalicylic acid (gives an excellent anti-inflammatory effect, is a non-steroidal substance).
- Paracetamol (the main purpose of the substance is to relieve pain and reduce fever).
- Caffeine (acts as an alkaloid that has a stimulating property and has a corresponding effect on the central nervous system).
Citramon also contains additional components (varie depending on the manufacturing company). Citramon tablets have a strong complex effect due to the wide composition of substances.
Previously, the drug was actively used due to its strong analgesic effect. In accordance with the instructions, it is recommended to drink Citramon for pain of moderate severity, in which the medicine is most effective (if the pain is severe, it is recommended to use potent drugs).
Citramon is a good help for people who develop inflammatory processes inside the body in various organs (the components of the drug help improve microcirculation in painful tissues). The drug helps reduce body temperature. When they say what Citramon P tablets help with, most often they are talking about lowering the temperature, although the medicine can have a beneficial effect on other symptoms of various diseases.
The caffeine contained in the medicine allows blood vessels to dilate after administration, as a result of which the work of various psychomotor centers in the brain is activated. The use of Citramon can slightly increase a person’s level of performance, eliminate fatigue, and relieve drowsiness. However, you should not take it too often and for preventive purposes - only if you have certain symptoms.
Indications for use
It is partly difficult to say what Citramon P tablets can specifically help with, because, given the composition of the drug, the medicine is a fairly universal remedy that provides high-quality medicinal effect on the human body for various disorders. Therefore, many doctors recommend having Citramon in your home medicine cabinet so that you can take it on time if there are appropriate indications.
- Citramon is one of the most popular drugs that are used for severe headaches. The components of the drug have a comprehensive effect on the root causes of pain, provide an excellent analgesic effect, so the pain syndrome is eliminated quite quickly. Along with the elimination painful sensations There is a slight improvement in the level of performance. This is why many experts recommend taking Citramon with you to work (especially if you work in an office). The main advantages of the medicine also include the fact that a person does not get used to the drug, even if he constantly takes it for a long time. One of the disadvantages of Citramon is that the medicine is not able to provide proper assistance if there are severe headaches (or pain in another part of the body). In this case, it is recommended to use potent drugs with a pronounced analgesic effect. Citramon is a symptomatic medicine, therefore it is not recommended to treat chronic diseases with it.
- From low pressure. Taking into account the inclusion of caffeine in the drug, taking Citramon can increase muscle and vascular tone and have a stimulating effect on the central nervous system. As a result of all this, blood pressure increases. Caffeine is contained in relatively small quantities, but it is strongly recommended not to drink coffee or black tea with the tablets, which also contain a high caffeine content. It is best to take Citramon with water.
- For toothache, many doctors also recommend starting treatment with Citramon. Here you need to take into account that this medicine has a beneficial effect and relieves pain if it is mild and moderately intense. With the help of the drug, you can quickly eliminate the initial pain in the teeth, reduce the level of development of the inflammatory process in the gums (for example, this is important for periodontitis and other dental pathologies). You cannot take Citramon for a long time to suppress pain in your teeth. You should see a dentist if possible, rather than temporarily treating oral symptoms.
- For a hangover. For withdrawal symptoms, it is also recommended to take Citramon, but only as a last resort, when no other available means help. The medicine quickly eliminates the symptoms characteristic of a hangover and improves the general condition of a person. It is strictly forbidden to drink Citramon in large quantities, because in this case, the liver will experience excessive stress, which, while drinking alcohol, can provoke various disturbances in the functioning of this organ. Drinking while taking the medicine is strictly prohibited.
- From high temperature. Citramon is one of the most common drugs that have an anti-inflammatory effect, which can be used by people of all ages, because belongs to the group non-steroidal drugs. The medicine helps reduce elevated temperature when this is caused by the development of an inflammatory process or cold symptoms. If the temperature is slightly elevated (no higher than 38 degrees), then you should not take pills - in this case, the body itself can cope with the problem that has arisen.
Instructions for use of the drug
If we talk about how to take Citramon, it is recommended that you first read the manufacturer’s instructions. It is not universal, because medicine of this type is now produced by many pharmaceutical companies, and therefore the principles of taking the drug, dosage, and timing may differ. It is also recommended to consult a doctor on this issue, if possible.
- It is recommended to drink Citramon after meals (it is best to take it with a small amount of water). Speaking about how many tablets you can take per day, it is recommended to take 1-2 tablets every 8 hours and no more often. The maximum daily dosage is 6 tablets.
- If the drug is used to lower the temperature or increase blood pressure, it is recommended to take the medicine for no more than 3-4 days in a row. If your blood pressure remains low, you should take strong medications or consult a doctor.
Many women use Citramon during menstruation to eliminate most of the unwanted symptoms. In this case, you can count on good healing effect(especially if the pain syndrome is mild).
Pregnant women are advised to use this drug with caution, since many manufacturers prohibit drinking Citramon tablets during the 1st and 3rd trimesters of pregnancy. At breastfeeding It is also not recommended to take the medicine, even if your head or teeth hurt very badly. In this case, you should seek help from specialists directly, or temporarily stop breastfeeding.
Contraindications and side effects
Before you find out what Citramon tablets help with, it is recommended that you familiarize yourself with the contraindications:
- Children's age up to 14 years.
- Kidney failure.
- High degree of excitement.
- Glaucoma.
- Erosion in different parts digestive tract.
- Hemophilia.
- Gout.
- Postoperative period.
- Vitamin K deficiency.
It is forbidden to take Citramon if a person has any contraindications. Despite its prevalence and demand, the drug is potent, therefore it will have a powerful negative impact if there are contraindications. You should not give the medicine to children under 14 years of age (even in small quantities), because there is a possibility that the drug will have a big negative effect.
The characteristics and action of Citramon have been well studied, so it has long been proven that many patients who have no contraindications to the use of the medicine can count on receiving positive result from taking the drug. Medicine Well tolerated by people of different ages and with different symptoms.
