Piroplasmosis is a seasonal vector-borne disease that is spread by ixodid ticks of the genus Dermacentor. On early stage it stops in 2 - 3 days with one injection. In advanced cases, they develop severe complications, up to the death of the animal. In this article we will look at how piroplasmosis develops in a dog, treatment, medications, and means of prevention.

How does piroplasmosis develop in a dog?

Nowadays in veterinary medicine the second name of the disease is more often used – babesiosis. Dogs become infected from March to October, when the air temperature rises above plus 5 degrees, and ixoid ticks wake up. Outbreaks are recorded from April to June and August-September. Previously dogs fell ill after walking in the forest, and now piroplasmosis is also diagnosed in city dogs.

Pyroplasmas enter circulatory system dogs. There they invade red blood cells, grow, multiply, and release toxic products. As a result, red blood cells disintegrate. Some of the blood cells are “eaten away” by piroplasms. But in severe cases, the bulk is destroyed by the animal’s own immunity. It perceives red blood cells as foreign agents.

The remaining blood cells cannot cope with their main task - saturating the cells with oxygen. The brain, heart muscle, liver, kidneys suffer from hypoxia:

• The heart and lungs work with redoubled force to restore normal level oxygen in tissues.
• Weakened kidneys cannot cope with the removal of destroyed red blood cells.
• The liver does not have time to process the toxic breakdown products of hemoglobin, which a huge number comes out of red blood cells.
• Accumulate in the body harmful products, intoxication occurs.
• Hypoxia and the action of toxins destroy brain cells.

Internal changes are more difficult for puppies, young dogs under one year old and older animals after 9 years.

Symptoms of acute and chronic piroplasmosis

The incubation period of piroplasmosis lasts 7–10 days. This is the average period. The first symptoms may appear after 3 days or after 3 weeks. In isolated cases, the disease develops within a few hours.

The first signs of acute piroplasmosis are changes in the animal’s behavior:

• the dog sleeps a lot;
• reluctant to go for walks;
• drinks constantly;
• eats poorly or refuses food altogether;
• the temperature rises sharply to 40 - 41 degrees.

Then the symptoms develop progressively:

• The animal is breathing heavily and rapidly.
• Moves with an unsteady gait or does not stand up at all when asked to paw.
• The color of urine changes: from dark yellow to blood brown.
• The mucous membranes dry out, turn pale, and then turn yellow.
• Signs appear eating disorder: diarrhea with mucus and blood, yellow vomit.
• The whites of the eyes and tooth enamel turn yellow.
• Heart rate increases.

Piroplasmosis occurs in the lungs and severe form. In the first case, symptoms are limited to an increase in temperature by a degree, lethargy and loss of appetite. In severe cases, most of the listed symptoms appear.

Chronic piroplasmosis develops in dogs with high resistance to the pathogen and in animals that have recently recovered from the disease. The symptoms are vague and can be easily confused with other diseases:

• The temperature rises at the beginning of the disease for 1–2 days, then returns to normal.
• The dog's health and behavior are unstable. Lethargy and apathy are replaced by periods of improvement.
• Diarrhea alternates with constipation, and the stool is sometimes yellow.
• Signs of anemia appear: mucous membranes turn pale, muscles weaken.
• Appetite periodically disappears, the animal becomes exhausted.

Pets suffer from acute piroplasmosis purebred dogs. Chronic form It often develops in strong stray animals, domestic mongrel dogs, and mixed breeds.

For any alarming symptoms the dog is shown veterinarian. If treatment is started immediately, the acute stage is stopped in 2–3 days. In severe cases, this will take 5–7 days. Then complications develop, and the recovery time after the illness increases. Acute piroplasmosis does not go away spontaneously. Without treatment, the dog fades away within a week.

Diagnosis of piroplasmosis

The doctor makes a preliminary diagnosis according to external signs, takes into account the season and where the animal walks. Symptoms of piroplasmosis resemble other diseases with similar symptoms: leptospirosis, kidney and liver pathologies, carnivore plague, poisoning. This is why the dog should not be left at home. Without accurate diagnosis The owner risks treating the dog for the wrong disease, wasting time and causing even more harm to the animal.

To clarify the diagnosis, the clinic conducts laboratory tests:

• Microscopic rapid analysis. Destroyed red blood cells and piroplasms embedded in them are found in the blood. Sometimes they are not detected, and the test shows a false negative result.
• Microscopic analysis of a stained smear. This diagnostic method is more accurate than the previous one. Peripheral blood is taken from the animal, usually from the ear. Then mixed with a solution that colors the cells and their elements in different shades. Pyroplasmas are painted blue, their nuclei are red-violet.

This is what piroplasmas (babesia) look like under a microscope.

Biochemical analysis of blood and urine shows the degree of change internal organs. It will be needed after cupping acute stage illness during recovery.

Piroplasmosis in dogs - treatment, medications

• destruction of piroplasms with antiprotozoal drugs;
• removal of intoxication;
• maintenance therapy.

A specific regimen is prescribed by a veterinarian depending on the severity of the disease.

Antiprotozoal drugs for the treatment of piroplasmosis in dogs

To destroy piroplasms, only 2 substances are used: diminazene or imidocarb. A lot of medicines are produced based on them:

Diminazene destroys the structure of unicellular organisms and leads to mass death of piroplasms. The drugs are available in powder form for dilution in sterile water for injection. The prepared solution is administered intramuscularly or subcutaneously once.

If piroplasms are detected in the blood a day after the injection, then a second injection is prescribed. The drugs contain an additional component, phenazone, which relieves fever, pain, and suppresses harmful bacteria.

Medicines with diminazene destroy piroplasms in the first hours after the injection, but they are toxic to the liver and kidneys. Animals often develop side symptoms. Vomiting and diarrhea develop. Increased salivation and urination, anxiety. Therefore, injections are never given without preliminary diagnosis. The dosage for the dog is selected by the treating veterinarian based on body weight.

Imidocarb blocks the entry of the vitamin-like substance inositol into red blood cells. Without it, piroplasms cannot exist and die. Medicines of the imidocarb group are available in the form of a ready-made solution for injection.

Injections are given subcutaneously 1 time. If the pathogen remains in the blood after 24 hours, the injection is repeated. Medicines should not be administered intravenously.

To alleviate the condition, the dog is injected with prednisolone: ​​2 mg per 1 kg of body weight twice a day for two days. He suppresses immune reaction, relieve signs of allergies, intoxication, stimulates the growth of red blood cells. Instead of human medicine You can inject a veterinary solution with prednisolone.

Additional medications during the recovery period

If the disease is caught at an early stage, the dog recovers safely without auxiliary medications. In severe cases, a drip is connected. Solutions of sodium chloride, ringer, and glucose 5% are administered. They restore the water-salt balance, enhance urine production, and toxic substances are released along with it.

Additional drugs are prescribed based on the results biochemical tests blood and urine. They show which organs need support. Your dog may need:

Here are examples of specific medications:

In case of renal or liver failure, plasmapheresis is prescribed. During the procedure, the blood is “driven” through filters. Dead cells of piroplasms and destroyed red blood cells settle on the membranes and do not affect the weakened kidneys and liver.

How to care for a dog and what to feed it

The dog's vivacity after the acute stage has been stopped is deceptive and does not mean full recovery. The disease affects all organs, so the animal is put on a gentle regimen for 2–4 weeks. Do not give physical activity, protect against hypothermia and overheating. Walks are shortened in time, but they are taken outside every 4 hours so that the dog empties his bladder on time.

A dog’s diet after piroplasmosis depends on which organs were damaged during the illness. The diet is developed by a veterinarian based on the results of blood and urine biochemistry.

Here general principles nutrition after illness:

• The dog is fed 4–5 times a day in small portions.
• If the tests are normal, the diet is not changed. The food is ground and served in a semi-liquid, boiled, warm form.
• The meat is boiled and cut into pieces. Then it is mixed with rice, buckwheat porridge or vegetable puree from zucchini and pumpkin.
• For variety, cottage cheese, kefir, fermented baked milk, plain yogurt, and boiled eggs are added to the diet.
• If kidney function is impaired, animal proteins are eliminated or reduced. Instead of beef, they feed dietary rabbit meat, turkey breasts and chicken. Small dogs can be temporarily transferred to meat purees for baby food.
• If tests show anemia, raw beef and liver are added to the diet. Before serving, the products are scalded with boiling water and finely chopped.
• The dog is on industrial feed dry granules are soaked in water. Canned food and pates are heated to 40 degrees. If the tests are bad, the pet is transferred to medicinal lines of the same brand with the usual food.
• Clean water is always left freely available.
• Once every 3-4 weeks, blood and urine are tested to adjust the diet.

After recovery, stable immunity to piroplasmosis is not formed. Dogs can become infected again, but they tolerate the disease more easily.

Prevention of piroplasmosis in dogs

The size of hungry ixodid ticks does not exceed 2–4 mm. They are difficult to see on dark or thick fur. Therefore, examinations after walks do not always protect against infection. The only way to protect your dog is to use tick protection.

Types of prophylactic agents against piroplasmosis

The preparations differ in the duration and degree of protection against pests, and the level of toxicity:

All preparations, except herbal ones, contain toxic components and give side effects. The more toxic the product, the better it protects against the effects of tick bites.

Preparations for the prevention of piroplasmosis in dogs

The table lists the names effective drugs by groups:

Nobivac pyro.

Piroplasmosis is a serious but curable disease. Its outcome depends on the sensitivity and efficiency of the owner. At the slightest alarming symptoms, it is better to take your pet to the clinic, where the doctor will diagnose piroplasmosis in the dog and prescribe treatment and medications. Recovery after the acute stage proceeds in different ways. For some, the disease passes without a trace, for others it reminds itself months and years later.

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In a hyperacute course, the disease develops without pronounced clinical signs, which causes the sudden death of the animal.
Acute course The disease is accompanied by high fever, depression, lack of appetite, and heavy breathing. body temperature rises to 40-41 C and can remain at this level for 2-3 days. The pulse is rapid, the visible mucous membranes are pale, cyanotic with a icteric tinge, the urine becomes reddish or coffee-colored, the animal weakens, the movement of the hind limbs becomes difficult and constrained. The chronic form of the disease lasts 3-5 weeks and is characterized by anemia, muscle weakness and exhaustion.

The diagnosis is made on the basis of clinical signs and epizootological data (detection of attached ticks on the dog’s skin). The results of microscopy of blood smears are decisive. But the absence of piroplasms in a blood smear does not exclude piroplasmosis. In such cases, when making a diagnosis, they rely on the course of the animal’s illness, medical history and the results of other laboratory tests (urinalysis, blood biochemistry, general analysis blood).

Treatment of piroplasmosis carried out in two directions:
1) destruction of the pathogen
2) removing intoxication and maintaining the general condition of the body

1. To destroy the pathogen, drugs from the group of organic dyes (brenil, azidine, methylene blue) are used. A common property of new drugs is their toxicity not only to the pathogen, but also to the patient.

INDEPENDENT USE OF THESE DRUGS IS DANGEROUS! THE DRUGS DO NOT HAVE A PREVENTIVE EFFECT; ADMINISTRATION THEM WITHOUT INDICATIONS IS MEANINGLESS!

2. To relieve intoxication and maintain the body, use a large amount medicines: saline solutions, vitamins, heart medications, etc. the volume and duration of treatment depends on the patient’s condition. In severe cases, IV drips and even blood transfusions may be required.
Anyway recovery period lasts at least one month and requires follow-up tests.

A LITTLE BIOLOGY

Ticks, the size of a raisin, belong to arachnids, i.e. have 4 pairs of legs. Males and females vary in size. Females are much larger than males. Only females drink blood. Having drunk blood, the tick increases several times in size and falls to the ground. Naturally, in this case they will not be detected.

The tick's mouthparts are about 1 mm in size and cannot cause significant damage to the animal. Damage is limited to a minor inflammatory reaction.

Flares have no head. The entire body is united into one gnathosoma complex (cephalothorax), to which the legs and mouthparts are attached. Ticks for a long time can survive without oxygen. Therefore:
1. Removing a tick does not require tricky techniques. You can remove the tick with thin tweezers, passing it between the skin and the tick. Lubricate the bite site with 5% iodine.
2. Watering a tick with oil is an activity for the patient!

Practical advice.

Mandatory inspection of the animal after walks. Ticks often attach themselves to the head, neck, chest, groin, in other places they are found much less frequently. It is advisable to inspect the animal twice with an interval of 1-1.5 hours.

Preventive treatment of dogs with modern acarecidal agents, which are available in the form of collars, sprays and drops on the withers. The point of using these products is based on the fact that the tick does not immediately dig into the skin, but crawls along it for 0.5-2 hours. These products are distributed over the skin and hair without being absorbed into the blood. When the tick comes into contact with “poisoned” hair and skin, it dies. These products, unfortunately, do not provide 100% protection against ticks. The effectiveness of these products depends on how much time has passed since their application.

READ THE INSTRUCTIONS CAREFULLY!

Protective equipment must be used in advance (2-3 days before going out into nature or going on vacation).
When purchasing protective equipment in veterinary pharmacies or pet stores, be sure to pay attention to the expiration date, integrity of the packaging, and instructions in Russian. Be sure to read the instructions!
Large companies (Bayer and Pfizer) have long supplied their products with instructions in Russian.

What to do?

Observe the animal carefully and inspect it regularly. If unreasonable lethargy and weakness, especially progressive ones, appear, yellowing of the visible mucous membranes and whites of the eyes, change in the color of urine to dark or red-brown, immediately show the dog to a veterinarian! The faster the animal is helped, the better the result will be.

The article is intended for the average pet owner and does not aim to bring higher academic knowledge to the masses. The task is very modest: to present in a short and clear form the essence of the disease, basic information about the carriers of the disease, and most importantly, what the owner can do to prevent this from happening or to ensure that the disease is noticed as quickly as possible. The article deliberately does not focus on treatment, because this is a matter for specialists.

Pathogen.
Life cycle Babesia occurs with a change of two hosts. Intermediate(in whose body asexual reproduction occurs) - a dog, and definitive (the definitive host in which sexual reproduction babesia) - mite.

Dogs become infected when bitten by infested ticks. Babesia goes through several stages during its development.
Trophozoites are single-celled organisms that develop in red blood cells and feed on hemoglobin. Trophozoites reproduce by simple division and form merozoites - two teardrop-shaped cells. Sometimes several pairs of merozoites accumulate in an erythrocyte. After reproduction, the erythrocyte is destroyed and merozoites are released into the bloodstream, then each of them penetrates into a new erythrocyte and becomes a trophozoite. In some individuals, division does not occur - they are called gamonts. When a tick feeds on an infected dog, the red blood cells, along with the trophozoites and merozoites, are destroyed in the tick's digestive tract. Only the gamonts remain, which penetrate the intestinal wall and turn into gametes. When two gametes fuse, an egg (zygote) is formed. The zygote forms a kinete, which penetrates the intestinal wall and migrates into the eggs of the female tick. The kinete divides and forms a colony of sporokines. When the female tick of the next generation, emerging from an infected egg, feeds on the blood of a dog, sporokines turn into salivary glands and become sporonts containing thousands of sporozoites inside. When bitten, the sporozoites enter the dog's bloodstream and become trophozoites. The cycle repeats.

Pathogenesis.
The pathogens themselves and the toxic products of their vital activity have an allergic effect on the animal’s body. Profound changes occur in the blood - acidosis, hypoglycemia, progressive hemolysis of red blood cells. Partial hemoglobin is converted into bilirubin and hemosiderin, and partially excreted in the urine. Bilirubin leads to the formation of hemolytic jaundice. Subsequently, due to liver damage, jaundice acquires a mixed (hemolytic-parenchymal) character. Vascular permeability increases, which leads to the formation of edema and hemorrhages. Hemolysis causes the development of hypoxia, reducing the possibility of neutralizing toxic products. Dystrophic and inflammatory processes in internal organs. Intoxication of the body increases. Irreversible changes occur in the central nervous system. In such cases, the prognosis is unfavorable.

Symptoms
Incubation period(time from the moment of infection to the onset of symptoms) ranges from 1 to 20 days (most often 3-4).
Distinguish acute and chronic course of the disease.
Acute course: In the first 2-3 days, body temperature rises to 40-41* (the norm for a dog is 38-39*). Dogs become lethargic, refuse food, and often experience shortness of breath. On the 2-5th day of illness, the color of urine changes (from bright orange to dark brown). The mucous membranes are pale, with a jaundiced tint. It is difficult for the animal to move, and sometimes paresis or paralysis occurs. On the 3-7th day of illness, the body temperature drops to 35-36* and the disease ends in death.
Chronic course. (occurs extremely rarely, about 2% of all cases of the disease). It is observed in dogs with increased resistance, outbred dogs, and those who have previously had piroplasmosis. Body temperature rises in the first 2-3 days, then decreases to normal. Animals are lethargic and get tired quickly. Appetite is reduced. Improvements in the condition are followed by periods of depression. Periodic digestive disorders. Characteristic signs are progressive anemia and exhaustion. The disease lasts from 3 weeks to 3 months and ends with recovery.
It is worth remembering that the disease often occurs with incomplete symptoms. Therefore, if at least one of the listed symptoms is detected, you should show the animal to a veterinarian.

Diagnostics.
The diagnosis is made based on the examination of blood smears stained according to Romanovsky. Microscopy reveals protozoa (babesia) inside red blood cells.

Our clinic has adopted a standard treatment regimen for piroplasmosis. It includes several mandatory tests blood and repeated examinations. This makes the entire treatment process somewhat more expensive, but it allows you to obtain data on the animal’s condition and prevent complications. You should not neglect the diagnosis and treatment prescribed by your doctor if you do not want to encounter problems and spend many times more money to combat complications. It is no exaggeration to say that these rules are written in blood. Based on our own experience and the experience of colleagues, as well as an analysis of literary sources, we made a diagram that covers the pathology development paths and allows the doctor to get an idea of ​​the dog’s condition and take adequate measures.

IN last years cases have become quite commonrelapses of piroplasmosis. Since some of the piroplasms are not in the bloodstream, but in parenchymal organs (often in the spleen, sometimes in the liver), they do not die during the administration of antiprotozoal drugs, and after some time they enter the bloodstream and can cause a recurrence of the disease. Therefore, we recommend for prevention purposes possible relapse re-inject the drug after 14 days.

Complications.
After suffering piroplasmosis, after a few days the animal’s condition may worsen again. This does not always mean that piroplasmosis has not been completely cured. In most cases, piroplasms are no longer in the body; these are the consequences of toxic and antigenic exposure.
Complications include: kidney, liver and heart failure, diseases of the joints, eyes, and neurological disorders.

Prevention.
Basic preventative measure is the treatment of dogs against ixodid ticks. For this purpose, collars, spot-on drops (on the withers) and sprays are used. For the drug to be effective, you must follow the instructions on the packaging. Various drugs They have individual terms of action and dosages, but there are some points common to all drugs.
1. Collars. Contain drugs long acting. From 1.5 to 8 months. They have a cumulative effect. The concentration of the drug on the surface of the animal’s body, necessary to effectively repel ticks, is achieved only on the 5-14th day of wearing the collar. Therefore, the collar must be put on in early spring, before the snow melts) The dog must wear the collar constantly and it must be very fit tightly to the neck. Removable only during washing.
2. Spot-on drops. Duration of action - 3 weeks. Start effective action 3 days after application. For better efficiency You should not wash your dog 3 days before and after applying the drops. Apply drops to the withers regularly throughout the warm season. The drops are valid for 28-30 days.
3. Sprays. If spring took you by surprise and you did not have time to put on a collar or treat your dog with drops in time, the only way to protect your dog today is a spray, since only this form of repellent acts instantly. The dog should be treated with the spray carefully, be sure to treat the entire surface of the body, including the face. In this case, there is a danger of the drug getting into the eyes and Airways To avoid this, instead of spraying the spray in the head area, apply it to a cloth and wipe the fur with it.

4. Tablets. They are given orally, begin to work 2-4 hours after administration and last 1-3 months (see instructions). In order for the drug to work, the tick must bite the dog; the drug enters the tick's body with the blood. This a good option processing in the event that you only remembered ticks on the way to the dacha and measures must be taken immediately.

In addition to treatments, it is necessary to examine the dog daily and, if ticks are found, remove them immediately. Even if the tick is infected, but has recently attached itself, there is a possibility that the piroplasms have not yet entered into the dog's blood, so it is important to remove the tick as quickly as possible.

There are vaccines against piroplasmosis Pirodog and Nobivac Piro.

Vaccines do not provide 100% Protection against infection with piroplasmosis, but in case of infection they significantly reduce the severity of the disease. The initial course of vaccinations consists of 2 injections with an interval of 3 weeks (immunity is formed 3 weeks after the second injection) then repeated every 6 months. Since the dog will be protected only 6 weeks after the start of vaccinations, it is advisable to start vaccinating the animal in the winter.

Unfortunately, no drug provides 100% protection against piroplasmosis and ixodid tick bites, so it is advisable to carry out comprehensive protection. If the animal is vaccinated, it is still worth treating it with repellents and inspecting it for ticks.

Be attentive to your pet; prevention is better than cure.

What is piroplasmosis? How to treat piroplasmosis in dogs?

What is piroplasmosis and how to fight it?

The disease has a pronounced seasonal nature: warm time year (spring-summer-autumn). Peaks of incidence occur in April-June and August-September.

The accumulation of hemoglobin breakdown products causes disruption of the functioning of internal organs: kidneys, liver, heart, central nervous system and others.
The incubation period for piroplasmosis is 7-14 days.

When treating piroplasmosis, therapy is carried out in two directions:
1. pathogen_destruction
2. removing intoxication and maintaining the general condition of the body

Information about piroplasmosis:

Piroplasmosis in dogs

Piroplasmosis in dogs has been very common in the Moscow region in recent years. It was also noted that due to warm winters and frequent thaws, the tick comes out of hibernation earlier... So, this year ixodid ticks have been noted in the Zvenigorod area since March 15.

Piroplasmosis treatment

Usually, treatment of piroplasmosis takes no more than three days, if the owners of the animal noticed their pet’s discomfort and consulted a veterinarian in time, and the dog does not have other diseases.
Treatment of piroplasmosis in dogs usually takes place in 2 stages - the introduction of an anti-pyroplasma drug, for example, PYROSTOP and massive infusions of solutions that relieve intoxication from the breakdown of red blood cells.

Vaccination against piroplasmosis, vaccine against piroplasmosis

Vaccination against piroplasmosis – new, convenient and reliable way keep your pet safe.
Your dog should be vaccinated against piroplasmosis in early spring and repeated twice a year.
The first vaccination is carried out twice with an interval of 3-4 weeks.

What you need to pay attention to - symptoms of piroplasmosis

The first symptoms of piroplasmosis are nonspecific - lethargy, loss of appetite or refusal to feed, fever.
Further, as a result of the development of the disease, jaundice appears, the urine turns brown-red, the color of tea leaves, which indicates the breakdown of a large number of red blood cells.

Analysis for piroplasmosis

Has all the necessary equipment to do an independent test for piroplasmosis. We take blood, stain it and look for signs of the presence of piroplasms under a microscope. Our clinic also allows blood collection for PCR testing.

Contact our specialists for help in a timely manner. We will test your pet for piroplasmosis, quickly and accurately make a diagnosis and prescribe effective treatment.

Canine piroplasmosis- an acute or chronic disease characterized by general weakness, increased body temperature, anemia (pallor) of the mucous membranes, hemoglobinuria (blood in the urine). There may be other symptoms associated with secondary lesions various systems and organs.

Symptoms of the disease.The disease manifests itself 1-7, in rare cases, 10 days from the moment the dog is infected and can be acute or chronic.
At acute form in dogs, body temperature rises to 41°C and above. General state becomes depressed. Animals lie down more, are inactive, their appetite sharply decreases and disappears. There is a change in the color of the urine (dark, bloody, brown). The visible mucous membranes of the mouth, nose and eyes are pale, and with severe liver damage they are jaundiced. Breathing is frequent, shallow, sometimes with shortness of breath. Rarely, vomiting and diarrhea may occur. In advanced cases, disruptions in the functioning of vital organs occur, kidney and liver failure develops, damage to the central nervous system occurs, the animal falls into a coma and dies.
The chronic course is usually observed in dogs with increased body resistance. The onset of the disease is often asymptomatic, and only on days 2-3 do they experience lethargy, fatigue, changeable and decreased appetite. Body temperature rises to 40-41°C, but the next day it may drop to normal or may be slightly higher. Most characteristic feature This form of piroplasmosis causes progressive anemia and exhaustion.

Diagnosisdiagnosed on the basis of epidemiological information, characteristic clinical symptoms ( heat and anemia of the mucous membranes) and by laboratory research(if piroplasms are detected in blood smears). Laboratory diagnostics is the main method for making a diagnosis, because clinical symptoms may be characteristic of other diseases (leptospirosis, acute inflammation of the urinary system, etc.)

Epizootology.The disease has a clearly defined seasonality (associated with the life cycle of ticks). There are two peaks: April-May and August-October.
Dogs of all ages are susceptible. Very young and elderly animals, as well as those who become ill again, are more severely ill. After suffering from piroplasmosis, immunity is not formed.

Prevention. The main means of preventing piroplasmosis are preparations for external treatment that repel ticks. Has maximum efficiency complex use drops on the withers "Frontline" once a month from April to October and constantly wearing a flea and tick collar for the same period. In areas heavily affected by ticks, additional treatment with Frontline spray.

For several years now, the PIRODOG vaccine has been used to protect against piroplasmosis. However, according to the Pirodog manufacturers themselves, this vaccine does not protect the animal from infection, but facilitates the course of the disease and reduces the risk deaths. Vaccination does not cancel external treatment measures.

Attention: Vaccination with Pirodog is carried out in our clinic by appointment.

PROCEDURE FOR VACCINE APPLICATION

The Pirodog vaccine is used to prevent piroplasmosis in dogs, starting from 5 months of age, twice with an interval of 3-4 weeks. Revaccination is carried out every 6 months in areas unfavorable for piroplasmosis and annually in areas free from piroplasmosis. Only dewormed and clinically healthy animals are vaccinated.

A quickly disappearing swelling may appear at the injection site. Some animals may experience apathy and decreased appetite after vaccination; these phenomena resolve on their own without treatment.

The Pirodog vaccine can be used together with a vaccine against rabies or leptospirosis. Other vaccines can be used before or after the use of the Pirodog vaccine after 2-3 weeks.