Ambrobene is an effective drug that is often prescribed for inflammatory processes occurring in the respiratory tract. A dry cough and difficult to separate sputum are the first signs, based on which the doctor prescribes this medication for treatment. Ambrobene for dry cough can be used in the form of tablets, capsules, syrup, drops, inhalation solution.
Ambrobene contains an active substance called Ambroxol. Once in the body, Ambroxol begins to stimulate the activity of the bronchial mucosa, enhancing the work of receptor cilia. As a result, the receptors begin to contract more intensely, and the removal of sputum is significantly facilitated.
In addition to stimulating the movement of sputum, when taking Ambrobene, it also liquefies. Ambroxol promotes the production of enzymes that are responsible for the action of polysaccharides. Under the influence of the drug, the connections are destroyed, the bronchial secretions become more fluid and pliable.
Ambrobene for wet coughs is prescribed not only for the rapid removal of sputum. This medication has a unique ability to enhance the effect antibacterial drugs in bronchial secretions, thereby contributing to the maximum effectiveness of the treatment.
Indications for the use of Ambrobene
The medication in question is intended for the treatment of infectious and colds, in which a cough with thick, difficult-to-discharge sputum is noticed. Without a doctor's prescription, this medication can only be used by adults and for only 5 days. If there is no improvement in your condition, you need to urgently seek qualified help.
The main indications for use are the following.
- Cough during acute respiratory infections and acute respiratory viral infections, which is accompanied by difficult to separate sputum.
- Dry cough due to colds.
- Viral or bacterial pneumonia.
- Laryngitis.
- Cystic fibrosis.
- Bronchial asthma.
- Scarlet fever, measles and other childhood infections, in which an attack of obsessive cough is expected.
How to take Ambrobene for cough
Ambrobene for wet cough shows good efficiency when removing sputum. If treatment is started on time, then with just one medication you can completely get rid of a wet cough. However, during therapy with Ambrobene, there is one main rule - you need to drink plenty of fluids. And it should be plain water, not juices or tea. It is necessary to drink liquid not only while taking the tablet or syrup, but throughout the entire treatment. This will enhance the effect of liquefying sputum and will promote its rapid removal.
Since Ambrobene is available in several different dosage forms, it is necessary to pay attention to the instructions for use of each type.
Solution for inhalation using a nebulizer
Thanks to the growing popularity of nebulizers, this form of Ambrobene is also beginning to occupy the first positions. Breaking down into volatile components, Ambrobene penetrates immediately into the respiratory tract, making the therapy most effective.
Inhalations with a nebulizer are carried out not only for adults, but also for children, however, before the first use, you should first consult with a pediatrician. The solution for inhalation is prepared immediately before use: for this, Ambrobene is diluted with sodium chloride in a special vessel (ratio one to one). It is better to purchase sodium chloride in a volume of 5 ml - this way you can use a fresh solution in each new treatment session.
Based on the instructions for Ambrobene, the amount of medication for inhalation for adults is 3 ml per procedure. The amount of solution for children is used depending on the age of the child. Approximate scheme: up to 2 years, 1 ml per procedure, from 2 to 6 years – 2 ml.
It is recommended to carry out the procedure with a nebulizer after eating, and it is not advisable to drink or eat within 2 hours. It is necessary to breathe the steam calmly, without strong inhalations and exhalations. If the procedure is planned for a child, try to hold him tightly.
Some people, after a procedure with Ambrobene in the form of inhalation solutions, may experience a disturbance in the perception of taste. This unpleasant effect disappears after 1-2 hours.
Ambrobene tablets (capsules)
This type of drug is the most popular, so in most cases doctors prescribe tablets or capsules for their adult patients. main feature When treated with this drug, you must take it whole, without splitting the tablets or opening the contents. Ambrobene must be taken with a large volume of liquid, and only after meals.
In each individual case, the doctor prescribes individual dosage regimens for the medication, but if your attending physician has not indicated a specific amount, you should adhere to the regimen that is in the instructions:
Attention: Ambrobene for a wet cough in a child under 6 years of age is usually used in the form of a liquid syrup.
- Adult patients take Ambrobene one tablet 3 times a day.
- It is preferable to give children one tablet 1-2 times.
Ambrobene cough syrup
Ambrobene syrup for dry cough is often used in young children. For correct dosage Manufacturers of the medicine included a special cup with serifs in the packaging, with which you need to calculate the required amount of medicine.
The manufacturer suggests dosing the syrup depending on the patient’s age.
- Up to 2 years, half a measuring cup 2 times a day is optimal.
- From 2 to 6 years - the amount of medication does not change, but the frequency of administration reaches 3 times a day.
- From 6 to 12 years - one whole measuring cup 3 times a day.
Some older children or elderly people, due to special circumstances, also prefer Ambrobene syrup. In this case, they need to take 2 standard doses 3 times a day. If the patient's condition improves, you can reduce the syrup intake to 4.
Ambrobene drops
Ambrobene can also be used in the form of drops for a dry cough in a child. To do this, the required amount of the drug is mixed with compote or juice, making the medication unnoticeable.
Since this form is usually preferred for children, the manufacturer has indicated the following scheme.
- For a child from 2 months to 2 years - 1 ml of Ambrobene once a day.
- 2 years - 6 years - 1 ml 3 times a day.
- 6 years - 12 years - 2 ml 3 times a day.
Possible contraindications to the use of Ambrobene
The drug in question is prohibited for use by pregnant women in the early stages, if Ambroxol or other components are individually intolerable, in case renal failure, diagnosed epilepsy or stomach ulcer.
Ambrobene is not recommended for use in the form of tablets or capsules for children; it is better to use syrup or drops. However, the syrup is used with caution in children with fructose intolerance. Ambrobene is prescribed with caution in case of impaired motor function of the bronchi, as well as in cases of diagnosed wet cough.
The drug Ambrobene has shown itself to be an effective remedy against dry cough, but in order for the treatment to be as beneficial as possible, it is necessary to strictly follow the proposed treatment regimens, provide the patient with plenty of fluids and prevent hypothermia.
During seasonal illnesses, you need to carefully observe preventive measures and replenish your home first aid kits.
Ambrobene for dry cough is one of the most effective medicines, which is suitable for a child or an adult.
A runny nose, fever and cough are among the most basic symptoms of ARVI. Properly selected medications will help you quickly cure a cold and avoid possible complications. The main thing to remember is not to self-diagnose or self-medicate. If the drugs are ineffective, you should immediately consult a doctor.
Treatment of productive and non-productive cough
Depending on the types of cough, special drugs and medicines are prescribed for its treatment. Of all existing drugs The drugs used in the therapeutic course can be divided into three main groups:
- Mucolytic drugs are drugs that help thin sputum, resulting in its rapid removal from respiratory tract person. These drugs include Ambroxol and Lazolvan.
- Expectorants act on the body in such a way that phlegm comes out as quickly as possible. The leading expectorant drugs are licorice root and Mucaltin.
- Antitussive medications can suppress the cough reflex in the brain. Often used for long-term and persistent cold symptoms. The most famous remedies from this group are Sedotussin and Bronchicum.
Treatment of a non-productive (dry) cough involves quickly transforming it into a productive (wet) cough so that the process of removing mucus from the respiratory tract begins. Complex therapy consists of drinking warm drinks, taking medications and, if not elevated temperature, the use of warm compresses.
Important! When treating a productive cough, you must take medications mucolytic and expectorant groups.
Such products help to quickly remove mucus, which speeds up the healing process.
In addition, highly effective cough treatment methods include therapeutic massage, rubbing and inhalation procedures. Today, inhalations with Ambrobene are often used for dry coughs.
Features and main characteristics of the medical product
Is it possible or not to take Ambrobene for a dry cough? Let's try to figure out what this medication is.
Ambrobene is a medical drug that is available in a variety of pharmacological forms, is a drug from the mucolytic group. The main effect of the drug is to dilute sputum and quickly remove it from the human respiratory tract. This remedy has an expectorant effect, which promotes rapid transition nonproductive cough into productive.
That is why, if the question arises about whether Ambrobene can be taken for a dry cough, the answer will be unequivocal: you can. This medication has proven itself to be a highly effective remedy in the treatment of nonproductive cough.
On a note! Main active ingredient medication Ambrobene is ambroxol hydrochloride, which begins to exhibit its properties within half an hour after administration and persists for 6-10 hours.
The main indications for the use of this medication are organ diseases respiratory system as a result of the formation of viscous sputum on the mucous membrane of the respiratory organs. Such diseases include:
- nonproductive cough caused by colds and acute respiratory viral infections;
- development of inflammatory processes in the respiratory system different forms;
- bronchitis in various forms (both acute and chronic);
- pneumonia;
- one of the types of bronchial asthma, which is accompanied by sputum production.
Thus, Ambrobene can be taken for dry or wet cough, depending on the nature of its origin.
In what forms is the medicine available?
Modern pharmaceutical companies offer their consumers various forms of release of this drug. Depending on the individual characteristics and needs, each person can choose the appropriate form of Ambrobene for himself.
Ambrobene can be presented in the following release forms:
- The tableted product is presented in the form of round tablets white with a dividing strip. The main active ingredient is Ambroxol; the auxiliary components are: corn starch, lactose monohydrate, silicon dioxide and magnesium stearate.
- A syrup that is great for treating babies. Ambrobene syrup is very actively used for dry cough in children. In 5 ml medicine contains 15 mg of active ingredient. The package contains instructions for use, the drug and a measuring cup to determine the required dose.
- The capsules contain a colorless gelatin base and are coated with a thin layer of dark shell.
- Solution for injections.
- The solution for internal use is a colorless, odorless liquid. When used orally, the medicine should be taken with a sufficient amount clean water, tea or juice. The package contains a measuring cup for convenient determination of the required dosage.
- A solution that is used for inhalation procedures. Suitable exclusively for nebulizers, that is, steam inhalations are prohibited with this solution. Thanks to such procedures, the discharge of sputum is accelerated, since Ambrobene penetrates faster into the tissues of the mucous membranes of the respiratory tract.
Additionally pharmaceutical industry produces this medicine in tablet form effervescent form and in the form of tablets with prolonged effects.
Features of taking the medication
The dosage and therapeutic course of treatment of Ambrobene directly depend on the release form medical product. In addition, age and general state patient's health.
The product in tablet format is taken during meals or immediately after it, washed down with a sufficiently large amount of clean water. The number of appointments per day for adults and children over 12 years of age is determined by the attending physician, taking into account the patient’s condition and the individual characteristics of his body. After three days, the course of treatment must be adjusted; in the process of adjusting the course, the effect of the drug on the body during the first three days of administration is taken into account. Only the attending physician has the right to clarify the dosage for further use of the drug. It should be noted that this drug in tablet form should not be given to children under 6 years of age. Persons aged 6 to 12 years can take 1/2 tablet 2-3 times a day, as recommended by the instructions for use. It should be remembered that taking the drug is allowed only on the recommendation of a doctor and in strict accordance with the dosages recommended by him.
Children willingly take the medicine in syrup form. In the instructions for use medical product the frequency of reception is indicated:
- for a child under two years of age - once or twice a day;
- a child under five years old can be given the drug no more than three times a day;
- for children from 5 to 12 years old, the recommended frequency of taking the drug is 3 times a day;
- Children (after 12 years) and adults are allowed to take the drug three times a day.
After the three-day course of treatment, you must switch to taking the drug twice a day.
When prescribing this drug for treatment, you should not rely on the instructions for use and prescribe dosages yourself. The required dosage and the frequency of use of the drug during treatment can only be determined by the attending physician.
Inhalations with Ambrobene are widely used for dry cough in children. To carry out the procedures, you must use a special device - a nebulizer.
Ambrobene solution is used for dry cough as follows:
- to prepare an inhalation mixture, it is necessary to mix equal quantities of the medicine with sodium chloride solution;
- the temperature of the resulting liquid should not be very high; the ideal temperature is equal to the temperature of the human body;
- When carrying out inhalation procedures, doctors recommend breathing calmly and evenly so as not to provoke a new coughing attack.
The permissible number of procedures may not depend on the patient’s age:
- For children under two years of age, a maximum of two procedures per day can be performed.
- For a child aged two to six years, it is recommended to carry out two procedures.
- Starting from the age of six, such procedures are carried out twice a day, 3 mg of the drug.
When performing inhalations with the drug for patients of different ages The concentration of the drug may differ. The volume of the drug required during inhalation and the number of procedures per day are determined by the attending physician.
When taking this drug, you should strictly adhere to all recommended dosages. There are restrictions when taking a medication that must be taken into account. It is prohibited to carry out treatment with this medicine in the following cases:
- during pregnancy;
- if there allergic reactions on the components of the product;
- stomach or duodenal ulcer;
- if there is an inflammatory process in the kidneys;
- with serious liver pathologies;
- patients suffering from epilepsy.
In addition, the drug in some cases can provoke a negative side effect. Such effects on the patient’s body manifest themselves as follows:
- From the respiratory system, rhinorrhea may develop, which manifests itself in the form of mucus leaking from the nose. There is a feeling of dryness in the respiratory tract.
- From the authorities gastrointestinal tract Diarrhea or constipation, nausea with vomiting, and a feeling of dryness in the mouth may develop.
- On skin Various allergic reactions may develop in the form of urticaria, itching or swelling.
Sometimes patients who are given droppers with Ambrobene solution complain of severe headaches, a feeling of fatigue and shortness of breath.
In case of non-compliance permissible dosages Nausea with vomiting, decreased levels may occur blood pressure.
Important! When purchasing Ambrobene at a pharmacy, you should remember that you can take this drug for a dry cough, but follow all recommendations and permissible doses.
What analogues of the drug exist?
It should be taken into account that the majority modern medicines, which belong to the mucolytic group and have an expectorant effect, contain one active ingredient - ambroxol hydrochloride.
The most popular analogues that can replace Ambrobene are:
- Ambrol.
- Ambroxol is available in various forms and with different dosages. Today it is one of the most affordable drugs for different types cough. It has an effective effect on the body if there are acute or chronic respiratory tract diseases. Suitable for therapy in patients of different ages with mandatory compliance with permissible dosages.
Can be used for cough various shapes drugs: syrups, tablets, capsules with expectorant properties. Among the many existing drugs that are in demand, it is worth highlighting Ambrobene.
Cough occurs due to the development inflammatory process in the respiratory tract, most often caused by infectious diseases. When you cough, the bronchi are cleared, so it is important to use effective means that contribute to this process.
Colds may be accompanied by dry or wet cough, and you need to understand which cough requires which medicine. With a wet cough, sputum is released. This condition is tolerated more easily by patients. The situation is more complicated with a dry cough, since it greatly irritates the mucous membrane. Ambrobene is used to alleviate just such a condition. It liquefies mucus and removes it.
Treatment of any colds need to start right away. If you start the disease, the likelihood of complications increases many times. You can start treatment with the remedy in question.
When can it be used?
Indications for use include diseases that occur with the appearance. Ambrobene is prescribed:
- when dry cold cough, for example, with tracheitis;
- lung diseases ( chronic forms and obstructions);
- chronic and acute form bronchitis;
- pneumonia;
- bronchial asthma, occurring with difficult sputum separation;
- bronchiectasis.
Release form
The following options are available:
- capsules;
- pills;
- solution for intravenous administration;
- syrup;
- inhalation solution;
- oral solution;
- soluble tablets;
- regular tablets.
Thanks to the variety of release forms, you can choose the one that is ideal for both adults and children
How does it work?
When using the drug in a way in which it does not enter the digestive tract, an immediate effect of the drug is observed. The duration of action after administration can range from 6 to 12 hours.
When taken orally, it also acts quickly, and its effect lasts for 8 hours. The drug is processed by the liver and excreted by the kidneys.
In tablet form
The active ingredient is ambroxol hydrochloride. You can take the medicine during or after meals with plenty of water. The tablets can be taken by children over 5 years of age.
Syrup
The instructions allow you to take the syrup even for children under 2 years of age, except for newborn babies and premature babies.
Flavoring is added to the syrup, so children drink it with pleasure. The product is bottled in dark glass bottles. It is taken similarly to the product available in tablets - during or after meals.
In capsule form
The product is a gelatin capsule, which contains medicinal substance. They can be taken only after meals, without chewing. Experts advise drinking it with plenty of water, as in this case the drug will work better.
The product in capsules can only be taken by patients over 12 years of age. But even after reaching this age (and for adults), the instructions prescribe to take only 1 capsule per day, it is recommended to do this in the morning.
Ambrobene for inhalation
Can be used for them mineral water or special inhalation solutions. Thanks to the use of an inhaler, such solutions enter directly into the mucous tissues and act immediately. You need to know that for steam inhalations such solutions are not suitable.
To facilitate the process of removing mucus from the respiratory tract, inhalations are often recommended
Solution
This form of release is intended for oral administration, and it is washed down with plenty of liquid. The solution can even be used to treat children under 2 years of age.
To prepare the mixture for inhalation, Ambrobene solution is diluted in equal proportions with sodium chloride. The temperature of the solution should be room temperature; inhalations should not be done with cold solutions. It is necessary to breathe evenly and calmly during the procedure.
Inhalations with Ambrobene for children under 2 years of age are done exclusively under the supervision of a doctor. Patients with bronchial asthma are advised to take bronchodilators before the procedure. This is necessary in order to avoid spasm of the respiratory tract.
Application of injections
This form can be used for intramuscular injection, and for subcutaneous and intravenous.
Ambrobene during pregnancy
Tests that could confirm complete safety during this period have not been conducted on humans. When tested on animals, no negative impact was not identified. In the first half of pregnancy (more precisely, up to 28 weeks), the decision to take medication can only be made by a specialist.
As for the lactation period, studies have shown that the drug penetrates into milk and enters the baby’s body during breastfeeding. Therefore, during this period, the decision to use should only be made by a doctor.
Contraindications and side effects
The medicine is widely used, but there are a number of restrictions. It should not be used when:
- individual intolerance to ambroxol and other components;
- stomach ulcer;
- duodenal ulcer;
- epilepsy;
- kidney diseases;
- in the first trimester of pregnancy.
People who have liver pathologies can take it exclusively under the supervision of a doctor. Situations in which respiratory tract diseases are accompanied by increased sputum production in the lungs also require attention.
The following may also appear: side effects:
- rhinorrhea and dryness in the respiratory canals;
- dry mouth and increased salivation, diarrhea, constipation, nausea;
- allergic reactions, in rare cases - contact dermatitis or anaphylactic shock;
- at intravenous administration: shortness of breath, headaches, chills, fever, fatigue, heaviness in the limbs.
In case of an overdose, there is a significant deterioration in health, blood pressure decreases, a feeling of nausea, vomiting occurs, and salivation increases.
In such cases, it is necessary to rinse the stomach (relevant within 1.5 hours after administration) and eat foods high in fat.
Ambrobene (tablets, syrup, solution, for inhalation) - instructions for use, price, reviews
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The site provides background information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!
Ambrobene refers to chemicals, which has an expectorant and sputum-thinning effect. The drug has a therapeutic effect in diseases with cough and difficult sputum discharge. Main active substance is ambroxol. Ambrobene also has an antioxidant effect: it neutralizes and removes damaging molecules called free radicals from the body.The drug reduces the viscosity of sputum and facilitates its outflow from the bronchi. Ambrobene works as follows:
- the drug stimulates the production of enzymes in the bronchial mucosa that break down the bonds between the substances that make up the sputum;
- activates the formation of surfactant (a mixture of active substances that prevent the alveoli of the lungs from sticking together);
- activates the function of the cilia of the bronchial mucosa, preventing them from sticking together.
Ambrobene penetrates in the highest concentration into the lung tissue and can enter breast milk, through the placental barrier and into cerebrospinal fluid. The effect after internal administration of the drug is observed within 30 minutes and lasts (depending on the dose) 6-12 hours. After administration as an injection, Ambrobene acts faster and lasts for 6-10 hours. Excreted from the body with urine.
Release forms
- Tablets – 30 mg, 20 pieces per package;
- Ambrobene retard capsules – 75 mg ambroxol, 10 or 20 pieces per package;
- Syrup (3 mg ambroxol in 1 ml) – 100 ml bottles;
- Solution for inhalation and internal administration (7.5 mg ambroxol in 1 ml) – bottles of 40 ml and 100 ml;
- Solution for injection in ampoules (15 mg ambroxol in 2 ml) – 5 ampoules per package.
Instructions for use
Indications for use
Ambrobene in any dosage form is used to treat chronic and acute diseases respiratory organs, in which there is sputum and its discharge from the respiratory tract is impaired: pneumonia, bronchitis, bronchial asthma, bronchiectasis.The drug is also used to treat respiratory distress syndrome in newborns (including premature babies) in order to activate the synthesis of surfactant.
Contraindications
- individual intolerance to any component of the drug;
- peptic ulcer of the duodenum and stomach;
- epilepsy and convulsive syndrome;
- functional failure of the liver and kidneys;
- secretion of sputum in large quantities and impaired bronchial motility due to immobile cilia (due to the threat of stagnation of sputum in the bronchi).
Side effects
- From the digestive tract (less than 1%): increased secretion saliva or dry mouth, nausea, vomiting, abdominal pain, bowel dysfunction (constipation or diarrhea).
- From the respiratory system (less than 1%): copious discharge from the nose, shortness of breath.
- Allergic reactions (less than 1%): skin rashes urticaria type, itching, facial swelling, fever, anaphylactic shock (isolated cases).
- Other reactions (less than 1%): headache, weakness, heaviness in the legs, chills, increased blood pressure, problems with urination.
- Pills: adults are prescribed 90 mg/day (1 tablet x 3 times) for 2-3 days, and then 30 mg/day (0.5 tablet x 2 times).
- Ambrobene retard capsules: adults: 1 capsule (75 mg) per day.
- Syrup: adults: 90 mg/day (10 ml x 3 times) for 2-3 days, then 60 mg/day (10 ml x 2 times).
- Ambrobene solution inside: for 2-3 days, 90 mg/day (4 ml x 3 times), then 60 mg/day (4 ml x 2 times).
- Ambrobene solution for injection: adults 30-45 mg/day (2 ml x 2-3 r.)
- up to 2 years – 15 mg/day (2.5 ml x 2 times);
- from 2 to 6 years – 22.5 mg/day (2.5 ml x 3 times);
- from 6 to 12 years – 30-45 mg/day (5 ml x 2-3 r.);
- over 12 years old - as for adults: 90 mg/day (10 ml x 3 times) for 2-3 days, then 60 mg/day (10 ml x 2 times).
- up to 2 years – 1 ml x 2 times/day;
- from 2 to 6 years – 1 ml x 3 rubles/day
- from 6 to 12 years – 2 ml x 2-3 rubles/day;
- after 12 years - as for adults: 90 mg/day (4 ml x 3 times) for 2-3 days, then 60 mg/day (4 ml x 2 times).
- Children under 2 years old – 1 ml x 2 times per day;
- 2-6 years – 1 ml x 3 rubles/day;
- after 6 years – 2 ml x 2-3 rubles/day
- children under 2 years old - 1 ml of Ambrobene solution 1-2 times a day (only under the supervision of a doctor);
- children from 2 to 6 years old – 2 ml x 1-2 rubles/day;
- children over 6 years old and adults – 2-3 ml x 1-2 r./day.
- Simultaneous treatment with Ambrobene and other antitussive drugs containing Codeine makes it difficult to produce sputum, because they suppress cough.
- Ambrobene improves the accumulation of antibiotics such as Erythromycin, Amoxicillin, Doxycycline, Cefuroxime in the lung tissue and bronchi.
- Ambrobene in the form of an injection solution cannot be mixed with solutions whose pH is higher than 6.3.
Ambrobene treatment
How to use Ambrobene?
Capsules and tablets should be swallowed whole, without opening the capsule or crushing the tablet. Ambrobene is taken orally after meals. The medicine should be taken with 200 ml of liquid: water, tea or juice. During treatment, the patient should be provided with plenty of fluids, because the drug dilutes sputum better if there is a sufficient amount of liquid in the diet.The drug has no effect on the speed of reaction and attention; there are no professional restrictions during treatment.
Patients diagnosed with diabetes mellitus should take into account that the syrup contains sorbitol as an excipient.
Ambrobene in solution for injection is administered intravenously by drip or slowly in a stream. Before administration, the drug is diluted with saline solution - 0.9% sodium chloride solution, Ringer-Locke solution or 5% dextrose solution.
Solution for internal use dose using a measuring cup included with the medicine package.
The use of the drug in the form of inhalations is described below (in the Ambrobene for inhalations section).
Ambrobene dosage
At functional disorders liver or kidneys, lower doses are used and with increasing intervals between doses of the drug. Only a doctor can prescribe a dosage regimen in these cases.
Overdose
Symptoms of a drug overdose may include nausea, vomiting, drooling, and decreased blood pressure. To help with an overdose, you should rinse your stomach and take fat-containing foods in the first 2 hours after taking the medicine.For dosages for children, see below in the section “Ambrobene for children”
Ambrobene for children
Ambrobene in tablet form is contraindicated in children under 6 years of age, and in the form of retard capsules - up to 12 years of age. Up to 2 years of age, Ambrobene can be used only as prescribed by a doctor and under his supervision. The drug is given orally to the child after meals with a sufficient amount of liquid (warm tea, juice, water, broth).Most convenient dosage form Ambrobene for the treatment of children - syrup. It is dosed using a plastic measuring cup: 1 ml of syrup contains 3 mg of active ingredient.
Doses of syrup for children
Doses of the drug in tablets
children from 6 to 12 years old – 0.5 tablets. x 2-3 rubles/day.Doses of the drug in capsules for children over 12 years of age
1 capsule (75 mg) per day, preferably at the same time of day.Doses of the drug for children in the form of an oral solution
Doses of the drug for children in the form of injections
Ambrobene solution for injection is administered to children subcutaneously, intramuscularly and intravenously (drip or slow stream). The solvent used is saline solution (0.9%) sodium chloride, Ringer-Locke solution, 5% solution of levulose, glucose.The dose of the drug is prescribed at the rate of 1.2 -1.6 mg/kg of the baby’s body weight.
For respiratory distress syndrome in newborns (including premature babies), the dose of the drug can be increased to 10 mg/kg body weight per day, and even up to 30 mg/kg body weight in severe cases. The daily dose of the medicine is administered 3-4 times a day. Discontinue the drug when symptoms disappear.
The injection solution cannot be combined in the same dropper (or syringe) with medications whose pH is higher than 6.3.
For the use of Ambrobene in the form of inhalations for children, see below in the section “Ambrobene for inhalations”.
For inhalations
In the treatment of respiratory diseases, you can also use a method such as Ambrobene inhalation. Sometimes it will be more effective than other routes of drug administration. This is especially true for the treatment of chronic diseases ( bronchial asthma, obstructive bronchitis, bronchiectasis).Benefits of this treatment: the medicinal substance immediately enters the bronchial mucosa and acts immediately; the drug has more effective action, which gives the smallest number adverse reactions; Ambrobene inhalations can reduce treatment time and doses of antibacterial drugs.
The drug quickly thins out thick, viscous mucus that impairs the patency of the bronchi. By coughing up sputum after inhalation, the patient feels significant relief. Using Ambrobene inhalations for bronchiectasis, you can achieve longer remission.
The bronchi are cleared of clear, viscous mucus by inhalation after an attack of bronchial asthma. To prevent the occurrence of an attack of bronchospasm provoked by inhalation, the patient is recommended to take bronchial dilators before the procedure.
For Ambrobene inhalation, a solution is used, which can also be used internally. In some cases, simultaneous administration of the drug orally and by inhalation is used, taking into account daily dose medicines. The solution is dosed using a measuring cup.
For inhalations, you can use any modern equipment (with the exception of steam inhalations). The most convenient device is a nebulizer, which converts the medicine into an aerosol that can penetrate hard-to-reach areas of the lungs and bronchi. This device is convenient to use both in the hospital and at home.
Before use, the Ambrobene solution is diluted by half with physiological sodium chloride solution and heated to 36-37˚C. The prepared solution is placed in a special container, then the inhaler is turned on. To prevent coughing during inhalation, you should breathe normally and not deeply. You can inhale the medicine using a mask placed on the face or through a special breathing tube (the mouthpiece is placed in the mouth).
Ambrobene dosages for inhalation:
During pregnancy and lactation
Experiments on animals did not reveal any teratogenic effects of Ambrobene on the fetus. There is no clinical data confirming the safety of the drug during pregnancy. Based on this, it is recommended to avoid prescribing the drug to pregnant women (especially in the first trimester).In the second or third trimester of pregnancy, the appointment of Ambrobene is permissible only by the doctor’s decision and in cases where healing effect will be higher than possible risk effects on the fetus.
Given that the drug passes into breast milk, a nursing woman can take the drug as prescribed by a doctor when assessing the balance between the benefits of treatment and the risk for the child.
For dry cough
The body's defense response to infection is coughing. If a dry cough occurs, treatment should be carried out without delay. A dry cough does not bring relief to the patient and can even cause complications - pneumothorax (air entering the pleural cavity upon rupture lung tissue) or pneumomediastinum (air entering the mediastinum due to bronchial rupture).A dry cough with inflammation in the respiratory organs should be converted to a wet one. This can be achieved with the help of Ambrobene, using any form of release of the drug. The easiest way to achieve the desired effect is through inhalation. Under the influence of ambroxol, the bronchial mucosa produces mucus, the sputum is liquefied and excreted.
In some cases, the cough may be dry even when sputum is in the bronchi, but is not coughed up due to impaired motor activity bronchi. In these cases, the use of Ambrobene is not indicated and even poses a danger.
Ambrobene drug interactions
Analogues
There are a number of analogues of Ambrobene based on the active substance (synonyms):Ambroxol, Ambrolan, Lazolgin, Bronhoxol, Ambrosan, Lazolvan, Bronhorus, Medox, Bronchovern Drops, Neo-Bronchol, Mucobron, Deflegmin, AmbroHexal, Remebrox, Halixol, Flavamed, Suprima-kof, ambroxol-retard.
Lazolvan or Ambrobene?
Manufacturers of drugs are different: Ambrobene is produced by the famous pharmaceutical company Ratio farm in Germany, and Lazolvan is produced in Greece and Italy. However, the active ingredient of both drugs is ambroxol. Therefore, the therapeutic effect of both Ambrobene and Lazolvan is almost the same: they dilute sputum and stimulate the cough reflex.Ambrobene has more dosage forms than Lazolvan, but at the same time, it also has more contraindications. Lazolvan can be used at any age. Both drugs are not recommended for use during pregnancy or breastfeeding. It is undesirable to prescribe both drugs for a wet cough.
Despite the similar mechanism of action, the drugs differ in the excipients in their composition, which should be taken into account when choosing a drug.
The price of Ambrobene is lower than Lazolvan.
A clear answer to the question “Which is better of these two drugs?” No. The drug is selected by the doctor individually.
Cough in children is often accompanied by increased viscosity of sputum, which makes it difficult to clear. Therefore, the main goal of treatment in such cases is to reduce the thickness of the mucus and increase the productivity of the cough. For this, various mucolytic drugs are used, including Ambrobene.
How does Ambrobene work and how effective is it?
Ambrobene is a German-made mucolytic. Active ingredient The drug - ambroxol hydrochloride - has the following effect:
- stimulates the movement of ciliated cells, thereby accelerating the removal of sputum from the bronchi;
- promotes the removal of sputum, cleansing the upper and lower respiratory tract from pathogenic microorganisms of various natures;
- improves the patency of small bronchi;
- increases local immunity;
- has an anti-inflammatory effect.
The effectiveness of the drug has been confirmed various studies, one of which was conducted in the winter and spring of 2002 by the Department of Childhood Diseases No. 1 of the Russian State Medical University among 208 children aged from birth to 15 years. Comparative analysis with some other mucolytics showed that treatment with Ambrobene accelerates the appearance of a productive cough, and the duration of therapy is reduced.
Ambrobene dilutes mucus well and removes it from the bronchi
Release forms
Ambrobene is available in different dosage forms, each of which has its own application characteristics and age restrictions.
- Ambrobene syrup does not contain thickeners or preservatives.
- The solution for oral administration and inhalation contains no flavorings, ethyl alcohol and sugar, so it is suitable for treating children with diabetes mellitus and impaired glucose tolerance.
- For severe chronic lung diseases, for example, bronchial asthma, taking Ambrobene orally together with inhalation through a nebulizer makes treatment more effective.
- Administration intramuscularly, subcutaneously or intravenously in combination with other drugs is justified for severe complicated pneumonia, respiratory diseases in newborns and after intubation anesthesia in children who often suffer from acute respiratory infections.
Sometimes you can hear that a solution for oral administration and inhalation is called drops. But there is a fundamental difference between these concepts. Drugs in the form of drops are dosed in the number of drops per dose. Ambrobene is available in the form of a solution, and its dose is measured with a measuring cap.
Ambrobene dosage forms - table
| Release form | Active substance | Auxiliary components | Age restrictions |
| Solution for oral administration and inhalation | ambroxol hydrochloride |
| in children under 2 years of age, use is possible only as prescribed by a doctor |
| Injection |
| contraindicated in children under 6 years of age | |
| Pills |
| not used to treat children under 6 years of age | |
| Capsules |
Shell composition:
| allowed from 12 years old | |
| Syrup |
| for children under 2 years of age, admission is carried out only on the recommendation of a doctor |
Indications for use
Ambrobene is prescribed for acute and chronic diseases of the respiratory tract, accompanied by a dry or unproductive wet cough with impaired formation and discharge of sputum:
- ARVI;
- spicy and Chronical bronchitis;
- pneumonia;
- bronchial asthma;
- bronchiectasis;
- pulmonary cystic fibrosis;
- tracheitis and laryngotracheitis;
- respiratory distress syndrome in newborns.
Doctor Komarovsky about the treatment of cough in children - video
Contraindications, possible side effects and overdose
Ambrobene is recognized as safe for children, so it can be prescribed to newborns and even premature babies. The main contraindication for treatment with the drug is individual sensitivity to the constituent components. In addition, the use of tablets and syrup should be abandoned if you are intolerant to lactose and monosaccharides, or lactase deficiency.
The medicine should be taken with caution if fixed cilia syndrome is accompanied by increased sputum production or occurs peptic ulcer stomach and duodenum in the acute phase.
The active substance is processed by the liver and excreted through the kidneys, so if these organs are diseased, you need to increase the time between taking Ambrobene and reduce the dosage of the medicine.
Treatment with the drug may be accompanied by adverse reactions, the likelihood of which varies:
- Often: nausea, taste disturbance;
- Rarely:
- dryness of the mucous membranes of the oropharynx;
- vomit;
- dyspepsia;
- stomach ache;
- diarrhea;
- allergic reactions.
Ambrobene should be stored out of reach of the child.
Uncontrolled oral administration of the drug can lead to an overdose, which manifests itself:
- nervous excitement;
- increased salivation;
- nausea;
- vomiting;
- diarrhea;
- decrease in blood pressure.
After opening the bottle, the drug is suitable for use for a year.
Instructions for use for children
The dosage, duration of treatment and dosage form are determined by the pediatrician based on the severity of the disease, the age of the child and the characteristics of the body.
- The syrup should be taken half an hour after meals, washed down with plenty of water.
- The oral solution can be added to compote or fruit juice. Dosing the medicine is made easier by using the measuring cup supplied with the medicine.
- The injection solution must be administered subcutaneously, intramuscularly or intravenously (using a dropper). Sodium chloride acts as a solvent.
Ambrobene begins to act half an hour after administration.
- Ambrobene should be taken no later than 2 hours before bedtime.
- For inhalation, it is recommended to dilute Ambrobene with saline solution (in a 1:1 ratio), which helps moisturize the mucous membrane and makes sputum less thick. You must first heat the liquid to a temperature of 35–37°C. Average duration procedures - 5 minutes. The course of treatment is 5–7 days.
A steam nebulizer cannot be used for inhalation with Ambrobene.
Ambrobene has some peculiarities in relation to combination with other drugs. It increases the concentration of the antibiotic in the alveoli and bronchial mucosa when joint reception what the treatment does bacterial infections lungs more effective. But the drug cannot be prescribed with cough suppressants. This will make it difficult to remove mucus from the bronchi.
How to perform inhalations correctly - video
What can replace Ambrobene?
Mucolytic drugs differ in their mechanism of action and effectiveness. They may be chemical or plant substances. Ambrobene has several analogues, for example, Lazolvan and Ambroxol. The choice of a specific drug is made exclusively by the doctor.
Comparative characteristics of expectorant drugs - table
| Drug name | Release form | Active substance | Indications | Contraindications | Age restrictions |
| Lazolvan |
| ambroxol hydrochloride | Spicy and chronic diseases respiratory tract, accompanied by the release of viscous sputum:
| hypersensitivity to ambroxol or other components of the drug |
|
| Ambroxol |
| ambroxol hydrochloride |
|
|
|
| ACC |
| acetylcysteine |
|
| from 2 years |
| Bromhexine |
| Bromhexine hydrochloride | Diseases of the respiratory tract accompanied by the formation of difficult-to-discharge viscous secretions:
| hypersensitivity to bromhexine |
|
| Mukaltin | pills | marshmallow root extract |
| increased sensitivity to marshmallow | from 1 year |
| Gerbion | syrup | liquid extract of spring primrose roots and common thyme herb | As an expectorant in complex therapy:
|
| from 2 years |
| Pertussin |
|
|
|
| from 3 years old |
