A characteristic symptom inflammation of the pancreas causes pain, which is especially intense during exacerbations. A patient with pancreatitis is unable to cope with acute pain, so medications come to the rescue. Which painkillers for pancreatitis will be more effective? What causes the acute pain? You will find answers to these questions in our article.
Reasons for the development of pancreatitis
There is actually no specific reason why pancreatitis occurs. The development of the disease can be influenced by many factors, for example, poor diet, alcohol abuse or lack of adherence to healthy image life. Due to these factors, the normal functioning of the pancreas is disrupted. Let's consider several main reasons influencing the development of pancreatitis:
In addition to the main reasons, an important role is played by genetic predisposition. Incorrect functioning of the pancreas can occur from birth. Exacerbating the situation with poor nutrition, pancreatitis develops.
Causes of pain with pancreatitis
Pain with pancreatitis can have a different character: stabbing, sharp, cutting, aching. If the patient cannot determine the location, most likely we are talking about inflammation of the organ completely. If the patient points to a certain point, this means that only part of the pancreas is affected. Some people complain of back pain, this is due to the fact that the pancreas degrades throughout the entire abdominal cavity, so the pain becomes blurred and radiates to the back. Please note that unbearable pain during pancreatitis is typical only during exacerbations of the pancreas or acute form of pancreatitis. IN chronic stage sensations of pain are observed much less frequently.
Painkillers
During an exacerbation of pancreatitis, the first step is to relieve an attack of acute pain. There are several types of painkillers, let’s look at them in more detail:
Antispasmodics
As a rule, pain with pancreatitis occurs due to spasm of smooth muscles. Antispasmodics can effectively relieve pain from this disease. Usually, in addition to antispasmodics, the doctor prescribes other medications.
Analgesics
With the help of analgesics, you can get rid of pain of almost any nature, including pancreatitis. Only if necessary, the doctor prescribes painkillers from a different group, for example, in case of acute inflammation of an organ.
Anti-inflammatory drugs
For acute pain during pancreatitis, in addition to taking painkillers, it is important to follow the following rules:
- Do not use cold as a pain reliever; this can aggravate the situation and increase vascular spasm.
- During acute pain, it is not recommended to eat food. Allowed to use boiled water in small quantities.
- Helps reduce pain intensity breathing exercises. You need to hold your breath for a short time, alternating with shallow breathing.
- Take a seated pose with your chest forward.
- Provide physical and moral rest to the patient.
- If necessary, call an ambulance.
Under no circumstances should you self-medicate pancreatitis. To avoid frequent exacerbations, you need to seek help from a doctor who will prescribe correct treatment. If treatment is followed, the patient achieves long-term remission.
In most cases, acute destructive-inflammatory pathologies of the pancreas are characterized by the appearance in the area abdominal cavity pronounced pain syndrome. That is why a therapeutic course aimed at ridding the affected person of the accompanying illness negative symptoms, involves taking painkillers medications.
Among them, for the most part, analgesics are used, but a drug such as papaverine for pancreatitis, despite the fact that it is an antispasmodic, is also used quite often for this purpose. This medicine has many positive reviews and ranks medicinal purposes, one might say, a leading position.
Pain relieving drugs
Elimination in the patient painful sensations is the most important task specialists involved in the treatment of pancreatitis. The choice of medications is made depending on the intensity of the pain. In addition, when selecting a drug suitable for a particular patient, the attending physician must take into account such important factors as the safety of the drug and the good tolerance of its components by humans. For pancreatitis, there are several types of first-choice painkillers:
- analgesics Baralgin, Pentalgin, Acetamifene, etc.;
- non-steroidal drugs (NSAIDs), which include Paracetamol, Voltaren, Indomethacin, Relafen and others;
- antispasmodics No-shpa, Papaverine, Buscopan.
Platyfillin for pancreatitis also has many positive reviews from patients and specialists. This medicine, like Papaverine or No-shpa, is an antispasmodic, that is, it can effectively relieve spasms from the smooth muscles of the digestive organs, thereby eliminating pronounced pain syndrome.
Essential Pain Relief Products
The choice of drugs that can quickly and efficiently relieve a patient’s pain in case of pancreatic pathology is presented in a fairly wide range in modern pharmacies.
Despite the fact that many products can be purchased without a prescription and at a fairly affordable price, self-medication for this ailment is strictly not recommended. When prescribing a therapeutic course suitable for the patient, specialists initially prescribe the safest medications from this group of drugs.
The transition to more powerful drugs occurs gradually. The main condition for this is the absence therapeutic effect from previously prescribed medications.
If adult patients with pancreatitis have signs of obstruction, that is, narrowing of the lumen of the duct, it is considered very important to prescribe them several methods at once designed to eliminate the pain syndrome:
- The first step is to ensure the free passage of pancreatic juice through the pancreatic ducts. The main method to achieve this is surgery.
- In parallel, medicinal therapeutic measures are carried out using antispasmodics and analgesics.
- In some cases, the patient may be prescribed intraductal lithotripsy, a laparoscopic operation during which the ducts connecting the pancreas to duodenum, expand mechanically.
- With this development of the destructive-inflammatory process in this digestive organ painkillers, analgesics and antispasmodics, selected by a specialist, are best administered intramuscularly. This way they can have a faster impact.
In the case when pancreatitis in a person occurs of the autoimmune type, in which immune activity increases as a result of some failure, and the system begins to destroy its own pancreatic cells, completely different medicines. Painkillers intended to solve this problem must contain ursodeoxycholic acid. The exact same medications are used for biliary disease, that is, developed against the background cholelithiasis, pancreatitis.
Medicines that relieve pain in the acute period
When asked by patients about what pills can be taken independently during the acute phase of pancreatitis, specialists always answer that this should never be done without first consulting with the attending physician.
Any pain reliever acute period pathology should be prescribed only qualified gastroenterologist based on the results of the diagnostic study.
But it can be noted that most often patients are recommended to take pills such as:
- No-shpa, Meteospasmil, Papaverine and Mebeverine, which have a good antispasmodic effect;
- analgesics Acetamifene and Baralgin;
- For drugs from the NSAID group, the greatest effectiveness is observed in tablets such as Indomethacin, Movalis and Voltren.
In the event that tablet drugs turn out to be ineffective in case of relapse of inflammatory pathology of the pancreas, the patient is prescribed injection forms medications. Thanks to this administration of the medicine, even the most acute sensations disappear in the sick person.
Also, in some cases, if the patient has very severe pain, he may be prescribed novocaine blockades.
If a sick person has signs of any serious complications of pancreatitis, for example, necrosis, doctors prescribe narcotic painkillers, Fentanyl or Promedol, to relieve very severe pain, which are used if the patient has appropriate indications and only in a hospital setting.
People with a history of a disease such as pancreatitis in any form and stage of development should firmly remember that all pain relief medications should be taken only after prior consultation with a specialist. Independently, at home, shoot acute attack Gastroenterologists prohibit the use of medications, as this may provoke the development of additional serious problems, which for the most part end on the surgeon’s table, and in some of the most severe cases, even with death.
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Translated from Greek, pancreatitis means inflammatory process, which occurs in the pancreas. The only correct decision of the doctor after establishing the diagnosis is to hospitalize the patient. If there is persistent pain, the patient is prescribed painkillers. Let us look at which painkillers for pancreatitis help best in this review.
Types of pancreatitis of the pancreas
The most important function of the pancreas is to produce digestive enzymes, breaking down carbohydrates, fats and proteins received from food. The activity of enzymes increases after they enter the duodenum.
If the duct is blocked, the enzymes are locked inside the organ. After some time, they become active again and begin to digest the organ cells. As inflammation develops, part of the pancreas is destroyed and replaced with connective tissue.
The main factor contributing to the development of this disease is alcohol abuse. For the development of pancreatitis, daily consumption of 150-200 grams is sufficient. strong drinks. Alcohol surrogate is especially dangerous.
Another common cause of development of this disease is poor nutrition. Abuse of high-calorie, fatty foods leads to stimulation of bile secretion and pancreatic secretion.
Sometimes pancreatitis is caused by the use of tobacco products, relapses peptic ulcer and nervous overexcitation.
The following types of this pathological condition are distinguished:
- Reactive.
- Spicy.
- Chronic.
Against the background of acute pancreatitis, its reactive form develops. The main provoking factor is the exacerbation of abnormalities of the gastrointestinal tract. At acute form inflammation of the gland tissue and its subsequent decomposition is observed. This leads to calcification of the gland. The chronic form is characterized by the gradual development of inflammation. Relapses alternate with remissions.
How does pancreatitis manifest?
Signs of an anomaly depend on its form and degree. At an early stage of the disease, a weakening of peristaltic sounds is detected. During tapping, doctors detect increased tympanitis.
Flow acute forms of pancreatitis are marked by the occurrence of mushy stools and nausea, which transforms into vomiting. Evacuated feces may contain incompletely digested pieces of food. Another sign acute shape is a change in shade skin. It becomes almost marbled, yellowish-blue spots appear in the navel area.
If acute pancreatitis becomes severe form, the patient's temperature rises or falls sharply. This condition is accompanied by shock or collapse. The following symptoms may appear:
- Chukhrienko's symptom.
- Mayo-Robson sign.
- Voskresensky's symptom.
The main symptom of the pathology is pain. It occurs first in the upper abdomen or in the left side, after which it moves to the areas of the back, sternum and shoulder blade. The main role in the development of pain syndrome belongs to obstruction of the pancreatic ducts, the development of dystrophic processes and disruption of tissue microcirculation. Additional negative impact provided by swelling. When edema appears, the tissues of the organ are greatly compressed.
Taking painkillers for pancreatitis
The primary task of doctors in treating this disease is to eliminate pain. Painkillers for pancreatitis are prescribed taking into account the intensity of the pain syndrome. The doctor is obliged to focus on the safety of painkillers.
If the doctor diagnoses low level pain, the patient is prescribed antispasmodic drugs and analgesics:
- no-shpa;
- buscolan;
- papaverine;
- pentalgin;
- baralgin;
- trigan-D.
During therapy, non-steroidal anti-inflammatory drugs such as Indomethacin, Relafen, Voltaren and Movalis are also used.
Treatment of acute pancreatitis with drugs
The main way to relieve pain in the acute form of the disease is to take analgesics. What painkillers help best with acute pancreatitis? Doctors recommend taking Paracetamol. This is a special drug that has minimal irritating effect on the gland.
Paracetamol is a hepatoxic drug. Patients with severe liver damage must obtain prior approval. The dosage of painkillers is selected by the doctor individually.
Also, in acute cases, patients are prescribed pancreatin tablets. Having no acid-protective membrane, they are activated in the upper part of the duodenum and in the stomach. Usually their use is combined with the use of medications that help block gastric secretion.
Treatment of chronic pancreatitis with medications
Therapy for the chronic form involves taking medications intended for enzyme replacement treatment. To reduce the intensity of pain, the patient is prescribed the following painkillers for chronic pancreatitis:
- panzinorm;
- Creon;
- pangrol.
In order to relieve pain sensitivity, a person is prescribed Somatostatin and Okreotide. By taking the medicine for three days, you can achieve a long-lasting effect.
To suppress gastric secretion, the doctor prescribes H2 receptor blockers to the patient. They have a powerful antisecretory effect. Their use may be combined with new medications such as Famotidine and Zantac.
Treatment of acute pancreatitis in a hospital
If drug therapy does not have the desired effect, pain relief for pancreatitis is carried out in a hospital. The patient can be given injections:
- Novocaine.
- Sodium thiosulfate.
- Diphenhydramine.
- Eufillina.
- Somatostatin analogues.
Diuretic medications are used to relieve swelling.
If the disease is very severe, the patient is prescribed strong painkillers for pancreatitis. Their use can be combined with analgesics that affect the central nervous system. Some patients are prescribed Imipramine and other psychotropic medications.
An exacerbation of the chronic form is characterized by an increase in the level of blood enzymes. Pain can be controlled with anticholinergic medications. In order to relax the sphincter of the hepatic-pancreatic ampulla, the patient is prescribed myotropic antispasmodic drugs.
Some patients are prescribed nitroglycerin. Patients also undertake to follow a diet prescribed by the doctor, excluding fried, spicy foods and foods rich in pesticides.
Comments on diet and traditional methods
The pain can be relieved on your own before the ambulance arrives. An ice pack is a great remedy. It must first be wrapped in a towel and placed on the stomach. The pain syndrome will subside a little.
It is allowed to give the patient a foot massage. Activation of biologically important points helps to temporarily relieve pain and relax the body. After the ambulance arrives, you need to provide the person with peace. For the next 2-3 days, the patient can drink unsweetened tea or high-quality mineral water.
Popular wisdom recommends using whey from yogurt, rosehip or mint infusion. Carrots and pomegranate juice, as well as zinc or magnesium mineral complexes. Prevention involves giving up tobacco, junk food and alcohol.
Inflammation of the pancreas, known in medical circles as pancreatitis, is one of the most common diseases in the world. modern world. Like many other diseases digestive system, it can occur in acute or chronic form, and its main symptom is abdominal pain.
The pain that occurs with pancreatitis causes a lot of pain discomfort the patient, and sometimes they are so strong and intolerable that they can lead to loss of consciousness. To alleviate a person’s condition, you need to know how and with what to relieve pain from pancreatitis.
Mechanism of pain
The intensity, nature and localization of pain in pancreatitis is influenced by multiple processes that occur in the tissues of the pancreas - obstruction and inflammation of its ducts, ischemia, degenerative changes. However, as most patients note, painful sensations occur 30 minutes after eating.
At acute pancreatitis An intolerable burning pain occurs, which increases every minute. The person is not being helped traditional ways pain relief – neither the “fetal position” nor the semi-sitting position. Usually the pain is localized in the upper abdomen, sometimes in the left hypochondrium.
The main symptom of acute pancreatitis is sudden pain that rapidly increases. Also, the acute form of the disease may be accompanied by the following symptoms:
- increased body temperature;
- increased heart rate;
- nausea and vomiting.
In the chronic form of the disease, a person is usually bothered by pain varying degrees intensities that can be localized in the upper abdomen, back and even lumbar region. Typically, pain intensifies after eating or drinking alcohol.
Sometimes it happens that after severe pain relief comes. You should not rejoice in advance, because this situation may be a sign of necrosis of a large area of the pancreas.
The main difference between acute pancreatitis and the chronic form of inflammation of the pancreas is the rapid development of the first option. IN in this case From the appearance of the first symptoms to the onset of irreversible processes in the diseased organ, 3–7 days pass.
The following factors can provoke an acute attack of pancreatitis:
- unhealthy diet and overeating;
- drinking alcohol;
- exacerbation of gastrointestinal tract diseases;
- taking some medical supplies;
- poisoning;
- abdominal trauma;
- stress.
How to relieve an attack of pancreatitis at home?
Pain during an attack of pancreatitis occurs suddenly. This can happen at home, at work, in transport or in the country. If you don’t have the necessary medications at hand, you can relieve pain and alleviate the patient’s condition using simple techniques.
If an acute form of the disease develops, the most correct and safe method of pain relief may be to apply an ice pack to the stomach. However, in some cases, an ice pack can only intensify vascular spasms and make it difficult for the diseased organ to function, thereby provoking a new and more severe attack of pain.
- provide physical and emotional peace;
- take a comfortable position sitting or semi-sitting;
- completely stop eating food;
- practice shallow breathing, which allows you to relieve some pain;
- take analgesics to relieve pain;
- call an ambulance.
In case of an attack of acute pancreatitis, you should not refuse hospitalization, since the result of untimely treatment medical care there may be internal bleeding
In case of exacerbation chronic inflammation pancreas, the patient may be recommended to take non-steroidal analgesics. First of all, we are talking about drugs such as Paracetamol, No-shpa, Ibuprofen, Diclofenac.
Anesthetic for pancreatitis is selected individually for each patient, and its dosage depends on the patient’s age, the form of the disease and the intensity of pain.
The patient's condition can be alleviated by a semi-recumbent position or the so-called “fetal position” (tucking the legs towards the chest). However, the main preventive measure pain in pancreatitis is to follow a diet that includes a complete abstinence from fried, fatty, spicy and salty foods, flour and bakery products, and alcoholic beverages.
An effective method of preventing exacerbation of pancreatitis is a three-day fast, during which the consumption of non-carbonated drinks is allowed. mineral water and tea with honey.
Following a diet will help restore the functions of the diseased organ and gradually eliminate acute pain
Yoga and some medical supplies However, these methods must be used very carefully and only with the permission of a doctor.
Painkillers for chronic pancreatitis
Answering the question about what medications can be prescribed for pancreatitis, gastroenterologists note that the choice of medications directly depends on the degree of damage to the pancreas and the intensity of pain.
To relieve pain and complex therapy In case of aggravated chronic pancreatitis, it is advisable to use the following groups of medications.
Pancreatic enzymes
Against the background of chronic inflammation of the pancreas, the patient may develop accompanying illnesses. For example, pancreatic enzyme deficiency. If this happens, the doctor prescribes enzyme preparations, which allow you to normalize the digestion process and significantly accelerate the restoration of pancreatic functions.
Enzymes are biological active substances, which improve the food conversion process.
There are three types of enzyme preparations:
- Single-shell (Pancreatin, Mezim) - allow you to slow down the process of self-digestion of the pancreas and reduce swelling. Used for intense pain.
- Double-shelled (Pancitrat, Creon) - protected by an acid-resistant shell, which allows them to mix evenly with food and improve its digestion.
- Combined (Dimethicone, Festal) - have a combined effect on the pancreas, improve the process of digestion of food, eliminate flatulence and bloating.
Combined enzyme preparations for acute chronic pancreatitis should be used very carefully, since bile acids, which are in their composition, can activate increased work of the pancreas, thereby increasing pain
Somatostatin and its analogues
The hormone somatostatin can quickly reduce pain throughout the body, including pain in the pancreas. The most common analogue of this hormone is Octreotide. Even short-term use of this drug can relieve pain from pancreatitis quickly and effectively. However this medicine has many side effects and is prescribed only for adults.
Histamine receptor blockers
These are medications that reduce production of hydrochloric acid. The most famous drug in this group is Famotidine. The tablets have a minimum of contraindications and suppress the secretion of hydrochloric acid very well.
Proton pump inhibitors
Like blocking drugs, proton pump inhibitors inhibit the secretion of hydrochloric acid and have virtually no side effects. Such drugs include Ezokar, Lansoprazole and others.
Painkillers for acute pancreatitis
Since the acute form of pancreatitis is accompanied by very severe pain, the primary goal of medical care is pain relief.
For this purpose you can use:
- analgesics;
- antispasmodics;
- narcotic and psychotropic drugs.
Injections
Pain in acute pancreatitis can be quickly relieved with the help of non-steroidal analgesics, which are administered intramuscularly. First of all, we are talking about No-shpa, Atropine, Analgin and Paracetamol. These medications are often prescribed with antihistamines(Diphenhydramine or Suprastin).
If the listed remedies turn out to be ineffective and the pain continues to increase, the patient may be prescribed narcotic drugs. So, cope extremely sharp pains with exacerbation of pancreatitis, drugs such as Tramadol, Promedol or Omnopol will help.
Strong painkillers for pancreatitis can only be used as prescribed by a doctor and only in a hospital setting
Pills
In acute forms of the disease, tablets are prescribed to restore pancreatic function. They are selected by the doctor individually for each patient, depending on the degree of damage to the pancreas and the presence of concomitant diseases.
Typically, patients are prescribed diuretics to relieve intoxication of the body, drugs to reduce enzyme activity, antibiotics in case of development bacterial infection, hepatoprotectors to maintain liver function, antiulcer agents and general health-improving drugs.
Antispasmodics
Antispasmodics are designed to quickly and safely relieve spasms in acute pancreatitis and relieve mild pain. This group of drugs includes Papaverine, Platiphylline, Atropine.
Instructions
Doctors prescribe the drug Baralgin for pancreatitis when pain in the inflamed pancreas cannot be relieved using other means. The medicine is available in the form of an injection solution, poured into ampoules. Due to the presence of several active ingredients Baralgin effectively relieves pain, eliminates spasms of the pancreatic ducts and reduces its swelling. In addition, the drug has a moderate antipyretic effect.
What drugs are prescribed to treat pancreatitis of the pancreas? View the general list.
Indications for use
Baralgin is used for acute and chronic pancreatitis, accompanied by mild pain or medium intensity.
Directions for use and doses
Baralgin is used intramuscularly and intravenously for exacerbation of pancreatitis. Single dose drug for intramuscular injection is 2-5 ml. If necessary, the injection can be repeated after 6-8 hours. The maximum permissible daily dose of the solution should not exceed 10 ml.
Intravenous administration of the drug is carried out slowly, with control blood pressure, pulse and respiration of the patient. The patient must be in a horizontal position. Daily dose solution at intravenous use is 2 ml.
Side effects
When using the painkiller Baralgin, a person may develop side effects as:
- increased heart rate;
- arterial hypotension;
- constipation;
- burning in the epigastric area;
- exacerbation of gastritis or stomach ulcers;
- dry mouth;
- dizziness;
- bronchospasm;
- renal dysfunction;
- interstitial nephritis;
- staining urine in a reddish tint;
- allergic reaction (urticaria, itching, rash, Quincke's edema, anaphylactic shock);
- decreased clarity of vision;
- pathological changes in the composition of the blood (anemia, agranulocytosis, leukopenia, thrombocytopenia);
- seals at the site of injection of the solution.
During development allergic reactions, impaired renal function or changes in blood composition Baralgin should be excluded from the treatment regimen for pancreatitis.
The components included in the solution can cause dizziness, blurred vision and other symptoms that can have a negative impact on control vehicle. For this reason, the drug is not recommended for use by people who drive a car.
Contraindications
Medicine Contraindicated for use in patients suffering from:
- hypersensitivity to its components;
- individual intolerance to non-steroidal anti-inflammatory drugs (NSAIDs);
- severe liver or kidney failure;
- megacolon;
- heart rhythm disturbances;
- hepatic porphyria;
- angle-closure glaucoma;
- bronchial asthma;
- intestinal obstruction;
- atonic condition of the gallbladder or bladder;
- benign prostatic hyperplasia II or III degree;
- blood pathologies.
In case of chronic gastrointestinal diseases, arterial hypotension, moderate disorders of the liver and kidneys, Baralgin should be used with caution.
Duration of treatment
Baralgin in the treatment of pancreatitis is allowed to be used for no more than 3 days.
Interaction with other drugs
You should avoid using Baralgin in combination with other analgesics or NSAIDs, because when these drugs are combined, their mutual enhancement may be observed adverse reactions. Combining the drug with thiamazole or sarcolysine increases the likelihood of developing leukopenia.
Baralgin reduces the effectiveness of indirect anticoagulants and cyclosporine. The combination of the latter with chlorpromazine can lead to a strong decrease in body temperature. Tranquilizers and sedatives increase the analgesic effect of the drug.
Baralgin should not be used in combination with oral contraceptives and tricyclic antidepressants, because this leads to increased toxicity of its constituent metamizole. The use of a solution in combination with phenylbutazone, glutethimide and barbiturates weakens the effectiveness of metamizole.
Baralgin is not compatible with . Alcoholic drinks reduce therapeutic effect medications and increase the severity of its adverse reactions.
Overdose
Exceeding the dose of Baralgin can lead to arterial hypotension, nausea, vomiting, decreased sweating, blurred vision, confusion, drowsiness, and impaired liver and kidney function. In case of overdose, the patient is prescribed forced diuresis and symptomatic treatment. If necessary, hemodialysis is performed.
