Bifidumbacterin is the active principle. Bifidumbacterin for infants - instructions for use, indications, analogues

Probiotic based on bifidobacteria. The effect of the drug is enhanced by the content of the nutrient medium and particles, thanks to which toxins are removed from the intestines faster, and the beneficial microflora is more intensely activated. Can be prescribed to children from birth with chronic disorders and acute conditions.

Dosage form

The medicine is available in powder form in sachets (bottles), capsules with powder inside, or rectal suppositories. Capsules and suppositories are prescribed to adults and older children, but for newborns and infants it is most convenient to use the powder in bags (bottles).

Composition of the product

The main active ingredient is bifidobacterium (Bifidobacterium bifidum), sorbed on coal particles. An additional substance, lactose, promotes the growth and reproduction of beneficial microorganisms.

The powder has a gray tint varying degrees color saturation with black splashes. The drug also has a characteristic odor fermented milk product. When diluting the medicine with water, a colorless solution with a precipitate is obtained.

1 sachet (bottle) contains 5 doses of medicine. One package of the drug can contain 10 or 30 sachets.

Pharmacological group and pharmacokinetics

Bifidumbacterin belongs to a group of drugs of biological origin intended to regulate the balance of gastrointestinal microflora.

The medicine acts exclusively at the local level, that is, in the gastrointestinal tract. Not absorbed into the blood. Does not provide negative impact on the functioning of other organs and systems.

Indications for use

The drug is prescribed to adults and children from birth to eliminate the following diseases/conditions/situations:

1. Various intestinal infections in acute form of established and unknown origin.
2. Food poisoning.
3. Chronic defecation disorders - diarrhea.
4. Disturbance of the balance and composition of the gastrointestinal microflora.
5. To restore natural microflora after antibiotic therapy, hormone therapy, treatment with chemotherapy and radiation therapy.
6. Inflammatory diseases of the gastrointestinal tract in chronic form.
7. Long-term dysfunction of the intestines.
8. Digestive disorder with impaired function of food digestion and absorption of nutrients.
9. Translation infant for artificial feeding.
10. Sepsis, anemia, malnutrition, in children. Including newborns and premature babies.
11. As part complex therapy allergic diseases.
12. Acute respiratory viral infections.
13. Pre- and postoperative period– correction of microflora in pathologies of the intestines, liver, pancreas.
14. For women, the drug is prescribed for:
    1. Prevention of inflammation of the mammary gland tissue of a woman in labor in case of a difficult epidemiological situation in the maternity hospital.
    2. Prevention and treatment of female gynecological diseases, including age-related ones.
    3. During preparation for childbirth, if the purity of vaginal discharge is impaired.

Contraindications

The manufacturer claims that the drug is very well tolerated by patients of all ages and has no special contraindications.

The medicine is not prescribed in case of individual intolerance (allergy) to the components of the drug. And also in case of lactose deficiency.

Directions for use and doses

1 sachet contains 5 doses. This means that if a child needs to be given 1 dose, the contents of the sachet are divided into 5 equal parts. Accordingly, 1/5 of the sachet is diluted with liquid, or the child is given 1/5 of the prepared solution.

Preparation of the drug solution - the contents of 1 sachet are poured into a clean, dry container and diluted with water at normal room temperature (not hotter than 20-35 degrees). Amount of water – 1 tsp. for 1 dose of medicine. Accordingly, 1 sachet of powder needs to be diluted with 5 tsp. liquids. The resulting mixture is shaken for 10 minutes; complete dissolution of the drug is not required.

The diluted medicine cannot be stored; it must be taken immediately after preparation. The part of the powder that remains undiluted in the open bag can be stored in the refrigerator for no longer than 1 day.

At intestinal disorders and diseases internal organs The drug is taken orally 20-30 minutes before meals. Infants The medicine can be diluted with breast milk or formula and given directly with meals.

If necessary, the medicine can be taken with meals or even regardless of meals; dilute it with fermented milk products, not water; add to liquid food.

In obstetric and gynecological practice, the drug is used intravaginally.

In the treatment of dysbiosis the drug is prescribed:

• Adults – contents of 1 sachet 3 times a day. The duration of therapy is determined by the attending physician and depending on clinical picture. On average - from 2 to 12 weeks.
• For newborn children – 1-2 doses 3 times a day. Children 6-12 months – 3 doses 3 times a day. Children over 12 months – 5 doses 3 times a day.

To prevent dysbacteriosis the drug is prescribed:

• Adults – contents of 1 sachet 2 times a day. Course – 7-14 days.
• Children – 2-3 doses of the drug 3 times a day.

To prevent mastitis– I treat the nipple area and around it with medicine half an hour before feeding the baby. To do this, 2 doses of the drug are diluted with water. Soak a sterile swab with the prepared solution and treat the desired area. Additionally, leave a cotton swab with medicine on the nipple before feeding. The course of treatment is 5 days.

For colpitis and others gynecological diseases, as well as in case of violation of the purity of vaginal secretions, the medicine is administered orally into the vagina. To do this, prepare a solution of 1-2 sachets of Bifidumbacterin. A sterile cotton swab is soaked in the solution and inserted into the vagina. The tampon is used once a day, leaving it inside the body for 3 hours. The course of therapy is 1 week or until signs of inflammation disappear and vaginal secretions clear.

For surgical pathologies– take the medicine 5 days before surgical intervention and for 2 weeks after it. Daily dose– 3-6 sachets.

For chronic diseases gastrointestinal tract The doctor may prescribe an increased dose of the drug. You need to take a 2-week course of medication, 5-10 sachets 1-3 times a day.

Regarding taking the drug for the treatment or prevention of other (listed above) diseases/conditions, you should consult with your doctor.

If necessary, the course of treatment with the drug can be repeated several times (after consultation with a doctor). Repeated therapy is prescribed no earlier than 30 days after the end of the previous one.

How to give the solution to an infant? There are several ways, you need to choose the one that suits you and your baby:

1. Give the medicine from a teaspoon, pouring it into the cheek.
2. From an ordinary medical pipette.
3. From a syringe ( without a needle!).
4. From the plastic cylindrical piston dispenser that is sold with many liquid children's medications (such as ).

Side effects

In accordance with the instructions, if the dosage is not violated, taking the drug cannot cause any negative reactions from the body. Even with long-term or repeated treatment.

Interaction with other drugs, effect on reaction rate

Taking the drug does not reduce or increase the effectiveness of other medications. May only slightly inhibit the effect of antibiotics.

The treatment does not in any way affect a person’s ability to operate machinery or a car.

The therapeutic effect of treatment with Bifidumbacterin can be enhanced by the simultaneous use of vitamins, especially those belonging to group B, or neutralized by the simultaneous use of antibiotics.

special instructions

The powder cannot be diluted hot water, or dissolve in a liquid (food) whose temperature is higher than the average human body temperature.

Do not store the diluted drug, even in the refrigerator.

It is prohibited to use the drug after its expiration date (indicated on the package).

Do not use the medicine if the integrity of the packaging is damaged or the powder has lost its physical characteristics.

The drug can be taken during pregnancy and lactation.

Overdose

The active component of the drug does not accumulate during prolonged exposure to the body and does not cause accumulation of signs of poisoning, therefore cases of overdose with Bifidumbacterin have not been recorded.

Storage conditions and periods

Store unopened sachets or bottles of powder in a dry, cool (+10 degrees) place. A short-term increase in temperature is acceptable environment(no longer than 10 days) up to +20 degrees.

The storage location must be inaccessible to children and pets.

Shelf life – 12 months from the date of manufacture.

Terms of sale in pharmacies

The drug is in free sale, its acquisition does not require a prescription from a doctor. At the same time, before purchasing and using the drug, you should consult your doctor.

Analogues of the drug

Instead of Bifidumbacterin, newborns can be prescribed the following medications:

1. belongs to Bifidumbacterin substitutes in the clinical and pharmacological group. The drug is sold in the form of drops for oral administration. They can be prescribed to children from birth, pregnant women and breastfeeding women. The drug helps normalize intestinal microflora and stop diarrhea.
2. Dinolak contains and as active ingredients. The medicine is produced in syrup, which can be given to infants and taken by pregnant and lactating patients. The medicine helps to regulate the microflora of the colon and eliminate it.
3. Biosporin is a substitute for the drug Bifidumbacterin in the clinical and pharmacological group. It is produced in the form of a lyophilisate for the preparation of a solution for oral administration. The drug can be used to restore intestinal and vaginal microflora in all patients age groups. They are allowed to undergo treatment during pregnancy and breastfeeding.
4. Florin forte contains bifidum and lactobacilli as its main components. The drug is available in powder form, which is taken orally. The medicine is approved in pediatric practice, during pregnancy and lactation.

Drug price

The cost of the medicine is on average 225 rubles. Prices range from 71 to 900 rubles

**** *PARTNER JSC* *PARTNER* ALLERGEN Alpharm, LLC BIOCAD, CJSC BIOMED Biomed named after I.I. Mechnikova, OJSC VITALFARM CJSC VITAPHARM VITAPHARMA FIRM, CJSC IMBIO IMMUNO-GEM CJSC IMMUNOPREPARAT, State Unitary Enterprise Lanafarm LLC MICROGEN NPO FSUE Microgen NPO FSUE Ministry of Health and Social Development Omsk Microgen NPO FSUE (Allergen) Microgen NPO FSUE Ministry of Health and Social Development of Russia/PharmV MICROGEN NPO Federal State Unitary Enterprise (Stavropol ) Microgen NPO, Federal State Unitary Enterprise of the Ministry of Health of Russia, Tomsk Microgen NPO, Federal State Unitary Enterprise of the Ministry of Health of Russia, PERM MICROGEN NPO, Federal State Unitary Enterprise of the Ministry of Health of Russia, Ufa MICROGEN NPO, Federal State Unitary Enterprise of the Ministry of Health of Russia, Nizhny Novgo PARTNER PARTNER JSC TYUMEN SUE BAKIPREPARATIONS ENZYME ENZYME Firm, LLC ECCO PLUS EKKO PLUS LLC ECOPOLIS ECOPOLIS CJSC EcoFlor, LLC

Country of origin

Canada Russia

Product group

Digestive tract and metabolism

Medical immunobiological drug(MIBP) - probiotic

Release forms

• Packages made of multilayer metal-polymer material (30) - cardboard packs. 10 - polymer cans (1) - cardboard packs. 10 - polymer cans (1) - cardboard packs. 20 - polymer cans (1) - cardboard packs. 30 - polymer cans (1) - cardboard packs. 40 and 50 - polymer cans (1) - cardboard packs. 10 doses - bottles (10) - cardboard packs. 1 - bottles (10) - cardboard packs. 10 doses - bottles (10) - cardboard packs. 1 - bottles (10) - cardboard packs. 10 pieces per pack 20 - polymer cans (1) - cardboard packs. 3 doses - bottles (10) - cardboard packs. 5 doses - bottles (10) - cardboard packs. 5 doses - bottles (10) - packs. 10 doses - bottles (10) - cardboard packs. 30 capsules per pack 30 tablets per pack 5 doses - bottles (10) - cardboard packs. jar 30pcs capsules - 10 pcs per pack. Lyophilisate for the preparation of suspension for oral administration and local application. 5 doses per bottle. 10 bottles in a pack (box) made of cardboard with instructions for use. 10 doses - bottles (10) - cardboard packs. Bags made of combined material (30) - cardboard packs. Bags made of combined material (30) - cardboard packs. Bags made of combined material (10) - cardboard packs. Packages made of multilayer metal-polymer material (10) - cardboard packs. Packages made of multilayer metal-polymer material (30) - cardboard packs.

Description of the dosage form

• Capsules Crystalline or porous mass of various shades of beige, light brown or whitish-gray with a specific odor. The drug is a microbial mass of live antagonistically active strains of bifidobacteria (Bifidobacterium bifidum 1 or Bifidobacterium bifidum 791), lyophilized in a cultivation medium with the addition of a protective sucrose-gelatin-milk drying medium Lyophilisate for the preparation of a solution for oral and topical use Powder for oral and local use Applications Powder for oral administration from light gray to dark gray in color with black coal particles and possible beige inclusions, with a faint sour-milk odor. Suppositories for vaginal or rectal administration, tablets, hard gelatin, body - white, cap - blue color; the contents of the capsules are a light gray to dark gray powder with black coal particles and possible beige inclusions, with a faint sour milk odor.

pharmachologic effect

Bifidumbacterin forte® capsules 5 doses is a microbial mass of living antagonistically active bifidobacteria of the species Bifidobacterium bifidum No. 1, sorbed on activated carbon particles, lyophilized, mixed with lactose and packaged in hard gelatin capsules (capsule body white, capsule cap blue). The contents of the capsules are a light gray to dark gray powder with black coal particles and possible beige inclusions, with a faint sour milk odor. BIOLOGICAL PROPERTIES The effect of the drug is due to bifidobacteria, which are antagonists wide range pathogenic (shigella, salmonella, Staphylococcus aureus etc.) and conditionally pathogenic (Proteus, Klebsiella, etc.) microorganisms. Bifidobacteria sorbed on a specially prepared carrier provide increased clinical effectiveness and rapid restoration of normal microflora. Microflora, being a natural biosorbent, accumulates significant quantities of toxic substances entering from the outside or formed in the body and decomposes them into non-toxic components. Sorbed bifidobacteria, forming microcolonies, intensively activate recovery and metabolic processes, parietal digestion, synthesis of vitamins and amino acids, immune protection body.

Pharmacokinetics

Special conditions

The simultaneous use of oral forms with antibiotics, as well as dissolution of the drug in hot water(above 40°) and storing it in dissolved form. The use of suppositories can be combined with the simultaneous administration of antibacterial, antiviral and immunostimulating medicines. Suppositories that smell like rancid oil or have broken packaging are not suitable for use.

Compound

• 1 caps. Bifidobacterium longum 50 million CFU 1 capsule contains: Active substance: bifidobacteria Bifidobacterium bifidum (sorbed on activated carbon) not less than 50 million CFU (5x10 7 CFU) Excipients: lactose monohydrate - up to 0.20 g. 1 vial. Bifidobacterium bifidum 10 doses 1 bottle. Bifidobacterium bifidum 10 doses 1 bottle. Bifidobacterium bifidum 5 doses Bifidobacterium bifidum dried suspension of living microbial mass of living, antagonistically active bifidobacterium strain Bifidobacterium bifidum, lyophilized in a cultivation medium with the addition of a drying medium - sucrose-gelatin-milk Composition (1 dose): Active substance: from 1 x10(7) to 5x10(7) live bifidobacteria or more than 5x10(7) live bifidobacteria Excipients: components of the protective drying medium* (gelatin; sucrose (sugar); milk) Composition of the protective drying medium (per 1 liter of medium): Edible gelatin, grade P-11 or K-13 - from 1.5 to 3%; White lump sugar or granulated sugar, or sucrose - from 5 to 20%; Skimmed milk powder or pasteurized skimmed drinking milk, or skimmed milk - pasteurized raw materials (in terms of dry matter) - from 8 to 25%;

Bifidumbacterin indications for use

• As monotherapy or as part of complex therapy: - intestinal dysbiosis; - established acute intestinal infections (shigellosis, salmonellosis, staphylococcal enterocolitis, rotavirus infection) and unknown etiology; - food toxic infections; - ARVI; - chronic diseases with damage to the gastrointestinal tract ( peptic ulcer stomach and duodenum, pancreatitis, cholecystitis, diseases of the liver and biliary tract), accompanied by intestinal dysbiosis; - chronic constipation; - malabsorption syndrome; - allergic diseases accompanied by intestinal dysbiosis; - pneumonia, acute and Chronical bronchitis, inflammatory diseases urogenital tract, accompanied by intestinal dysbiosis; - intestinal dysbiosis caused by taking antibiotics, antibacterial drugs, hormones, NSAIDs; - diarrhea in patients receiving long-term treatment with antibiotics and other antibacterial drugs; - correction of intestinal microbiocenosis and prevention of purulent inflammation
• store in a dry place
• keep away from children
• store in a place protected from light
Information provided

It is difficult to overestimate the role of antibiotics for humanity. They have certainly saved many lives due to their high effectiveness in combating various infections. But despite this, antibiotics also have side effects. One of them is an extremely adverse effect on the intestinal microflora. Antibiotics do not choose which bacteria and microorganisms they destroy - harmful or beneficial. Everyone gets hit. Because of this, the beneficial and much needed intestinal microflora suffers. Bloating and stool upset appear. This is why it is so important not to overuse antibiotics and take them strictly as prescribed by your doctor. After all, due to the fact that beneficial microflora suffers, such an unpleasant phenomenon as dysbacteriosis develops. Even the immune system can suffer because of it. But very often antibiotics are really necessary. So what should we do? How to ensure that after treatment with antibiotics the beneficial intestinal microflora suffers minimal damage? In order to somehow protect yourself and minimize bad influence antibiotics, drugs are used that can optimize the intestinal microflora. They should be used in parallel with antibiotics. Then there is a chance that the intestinal microflora will be maximally protected. These drugs are called probiotics. We will look at one of the most famous and frequently used probiotic agents - Bifidumbacterin. If you are prescribed Bifidumbacterin or Bifidumbacterin forte, the instructions for use will help you figure out what doses to take, with what frequency, and how to properly prepare the suspension.

Bifidumbacterin has long been used in medical practice. It is a well-known probiotic. Probiotics are a group of drugs and dietary supplements that contain live microorganisms. These microorganisms are representatives of the beneficial microflora of the human intestine. They help restore normal functioning of the gastrointestinal tract, eliminate acute and chronic disorders intestines. As the name suggests, Bifidumbacterin contains bifidum bacteria. Its strains are grown on a special nutrient medium and then dried. Most often, this drug is taken in the form of a suspension. The suspension is prepared from the powder contained in ampoules. This powder is diluted with boiled water at room temperature, milk or fermented milk product. When it is diluted with water, the result is a cloudy liquid. If you have been prescribed Bifidumbacterin, the instructions for use will help you use the powder to prepare a suspension.
Bifidumbacterin is very useful for the gastrointestinal tract. It significantly improves its performance. The drug also helps normalize metabolism. Thanks to this, the body begins to receive more nutrients from food, and they are better absorbed. Bifidumbacterin is often prescribed for various diseases intestines, both acute and chronic. Its beneficial microorganisms help cope with toxins. It has also been noticed that due to the improved functioning of the intestines, there is an increase in immune system. The body becomes more resistant to the influence of infections and other pathogenic factors. If there are problems with the intestines, then it is advisable to take the drug orally. If there are problems with gynecological pathology, then Bifidumbacterin is used intravaginally or externally.

For gynecological problems, you need to prepare a suspension, as usual, moisten a sterile tampon in it and insert it inside the vagina for 2-3 hours. Use only freshly prepared suspension. The instructions and doctor's prescription will help you choose the dose of the drug. The instructions describe exactly what dose will be required at a specific age and for the treatment of specific diseases. The doctor will help you calculate correctly effective dose. It will depend on various factors: complexity of the disease, age.

When should you take Bifidumbacterin?

Bifidumbacterin is used for the following pathologies:

1. Disruption of the normal state of beneficial microflora in the intestines (dysbacteriosis);
2. Acute intestinal infections (viral diarrhea, dysentery, salmonellosis, etc.);
3. Syndrome of impaired absorption from the gastrointestinal tract;
4. Chronic constipation;
5. Foodborne infections with toxic consequences;
6. Before and after operations, if there are problems with the gastrointestinal tract, liver or bile ducts;
7. Pi allergies, which manifests itself in the form of dysbacteriosis;
8. If a child or adult often suffers from ARVI;
9. After long-term treatment antibiotics during the recovery period;
10. After hormonal or radiation therapy;
11. If infant switches to artificial feeding too early;
12. IN complex treatment newborn or premature babies;
13. In gynecology for dishormonal vaginosis and staphylococcal colpitis;
14. Preparing a pregnant woman for childbirth if the vaginal cleanliness is grade III or IV.

What may be contraindications to taking Bifidumbacterin?

There is no data yet on any conditions in which the use of this drug would be contraindicated. But it must be taken when needed.

If this medicine is taken correctly, taking into account all the requirements of the instructions, then side effects must not be. It is important to prepare the suspension correctly and comply with the required dosage. Despite the fact that this drug has virtually no contraindications, take it after your doctor’s prescription!

What precautions should you take?

You should not take Bifidumbacterin orally at the same time as using antibiotics. If you are undergoing treatment with antiviral drugs or antibiotics, then it is better to opt for other forms of Bifidumbacterin. These could be candles.

Vitamins from group B can enhance the effect of Bifidumbacterin.

Do not use a medicine that has already expired. If you notice that the packaging is damaged, also refuse to use it.

According to patients who have already taken Bifidumbacterin, as well as doctors who have been using it in their practice for a long time, thanks to this drug, the patient’s body not only restores beneficial microflora, but also strengthens the immune system.

Is Bifidumbacterin useful?

Bifidumbacterin is well known as an effective probiotic that can be used from the first days of life. It is prescribed even to newborns in order to quickly normalize the microflora of their immature intestines. It is produced in various forms: bottles, ampoules, candles, powder, capsules. What does this miracle drug consist of? Bifidumbacterin, which is sold in ampoules or vials, contains bacteria that have been specially dried. These are live bacteria that have been first frozen and then dried. This Bifidumbacterin quickly provides the body with live bacteria (10*7). In addition to the bacteria themselves, this drug also contains auxiliary substances. They are grown and preserved in a medium of milk, sugar and gelatin.

You can use other forms of Bifidumbacterin. The powder of this drug, for example, contains a mass of living microbes in an amount of 10 * 8. These microbes were previously purified from their growing environment, unlike those in ampoules and vials. But if you come across the drug Bifidumbacterin-forte, then this prefix means that it contains colony-forming organisms. To immobilize them, a bone stone is used Activated carbon. This technique is called immobilization (immobilization). Thanks to it, Bifidumbacterin in powder form is used to locally colonize certain mucous membranes. This technique is used when you need to quickly restore normal microflora in the gastrointestinal tract. Bifidumbacterin-forte can be either in powder or capsules. Each capsule contains five doses of beneficial bacteria.

How to take Bifidumbacterin correctly?

Let's start with the fact that despite all the usefulness and apparent harmlessness of this drug, it can be taken strictly as prescribed by a doctor. He will help you choose the form of medication that will be most convenient and optimal for you. When taking the drug, strictly follow the instructions. Since Bifidumbacterin contains a lot of active and beneficial bifidobacteria, it can quickly normalize the state of the gastrointestinal tract. It will help improve the digestion process and eliminate dyspepsia. Thanks to Bifidumbacterin, the body also develops resistance to adverse factors and toxic substances.

Bifidumbacterin is prescribed for of various origins dysbacteriosis. By the way, not only antibiotics can provoke dysbiosis. It may occur due to anti-inflammatory non-steroidal drugs, hormones, courses of treatment with certain medications. Even severe stress can trigger the appearance of dysbiosis. It is very useful to use Bifidumbacterin in cases where dysbacteriosis occurs against the background of various pathologies of the digestive tract, liver, and bile ducts. It is also used to alleviate the condition of patients with pneumonia, bronchitis (chronic), and urogenital inflammation.

In addition, Bifidumbacterin is also used for acute intestinal infections(staphylococcal enterocolitis, rotavirus, salmonellosis, shigellosis), as well as foodborne toxic infections. If the patient suffers from an intestinal infection of unknown origin, then Bifidumbacterin is used to combat it. This unique drug helps with malabsorption syndrome, bacterial colpitis, and to combat constipation. For vaginosis, it helps restore the vaginal microflora. Sometimes doctors may prescribe Bifidumbacterin to eliminate the effects of allergies if they are associated with manifestations of dysbacteriosis. It is indispensable for pathological conditions not only the intestines, but also the liver and pancreas. Before various kinds operations Bifidumbacterin helps restore the microflora of the intestines and digestive tract as a whole.

This probiotic can even be prescribed to a nursing mother to prevent this. dangerous phenomenon like mastitis.
So, we see that Bifidumbacterin is very widely used to treat adults. Its probiotic properties have long been recognized and are difficult to overestimate. But its scope of application is not limited to this. The use of Bifidumbacterin for newborns gave excellent results. Its use is especially important for those babies who are bottle-fed, donor-fed or mixed-fed. This unique medicine helps balance beneficial and opportunistic bacteria in their immature digestive tract. Newborns often experience such an unpleasant phenomenon as colic. Doctors have not yet fully established their exact cause and mechanism of development, but it has been noted that the use of probiotics, and in particular Bifidumbacterin, reduces their frequency. And after the baby is three months old, colic usually stops bothering him at all.

Taking Bifidumbacterin correctly

In order for the therapeutic effect of this drug to be maximum, you need to take it correctly. The doctor will prescribe you a specific form of the drug and select the optimal treatment regimen for you. We have already mentioned that the drug is available in different forms. It can, accordingly, be used not only orally, but intravaginally and rectally. For newborns, it is advisable to use the drug during direct feeding. To do this, it must be diluted in a mixture or breast milk. There is another option. You can treat the nipple and areola directly with a prepared suspension of Bifidumbacterin before feeding the baby. To do this, you need to take a sterile cotton swab and soak it in the resulting liquid (2.5 doses over 5 days). This manipulation should be done half an hour before feeding. Then there will be strains of beneficial bacteria on the nipple, which will reach the baby during feeding.

To prepare the suspension, you need to take a teaspoon of water (boiled). Its temperature should be no higher than 40 degrees so that the bacteria do not die. Water is added to the bottle with dry Bifidumbacterin. The resulting suspension should be taken immediately, before meals, 20-30 minutes. It is unacceptable to store the prepared suspension, as it completely loses its medicinal properties.

For older children, Bifidumbacterin should be diluted in boiled water (30-50 ml) or any fermented milk product. The diluted drug should be used immediately to beneficial bacteria didn't die. It is better to do this within 2-3 minutes. Until they reach six months, children are prescribed one sachet of Bifidumbacterin per day. It is divided into 2-3 times and taken before meals. Older children can take the drug more often – 4-6 times a day. For children aged six months to one year, one sachet is prescribed three times a day. From three to seven years old, one sachet is prescribed 3-5 times a day. For older children (from 7 years old) and adults, it is acceptable to use two sachets 3-4 times a day. This treatment usually lasts three to four weeks. In case of correction acute infections intestines, the drug should act for five to seven days.

Sometimes the drug is prescribed for prophylaxis. To prevent dysbiosis in newborns, one sachet is used once a day, from six months - 2 sachets 1-2 times a day.

How to use Bifidumbacterin suppositories correctly

The oral form of Bifidumbacterin is most often used. But do not forget that it can also be in the form of candles. Suppositories are prescribed for problems with intestinal microflora. They are used as follows. The suppositories need to be administered three times a day, rectally, one or two pieces at a time. The exact quantity and regimen of use is prescribed exclusively by the doctor. Along with the use of suppositories, it is advisable to take this drug orally. This way you can achieve maximum therapeutic effect. The course of treatment will be from two to four weeks. It depends on the complexity of the disease and individual characteristics the patient's body. At acute course treatment of the disease will take 7-10 days. Suppositories are also used for intravaginal use. In this case, one suppository is inserted into the vagina twice a day. The course of treatment is 5-10 days.

Bifidumbacterin analogs

Like many other medicines, Bifidumbacterin has analogues. The active ingredient in them is approximately the same. Yes, and the principle of operation is the same. Analogues of Bifidumbacterin are the following drugs:

• "Bifinorm";
• "Biomass of bifidobacteria";
• "Probifor".

As can be seen from all these names, active substance they contain beneficial bacteria. They were grown on a special nutrient medium and when they enter the body they begin to multiply on the mucous membrane.

So, Bifidumbacterin is effective and safe means to combat various pathologies. The main thing is to use it rationally and in compliance with the dosage.

Bifidumbacterin is a preparation that consists of a microbial mass of living but dried bifidobacteria immobilized on stone fruit. Bifidumbacterin, instructions for use of which are given below, contains at least 10^7 CFU of bifidobacteria in one sachet.

Pharmacological properties

The therapeutic effect of bifidumbacterin is due to the living bacteria it contains, which have antagonistic activity against a large number of pathogenic and opportunistic microorganisms. The high content of bifidobacteria contained in the preparation makes it possible to normalize the intestinal microflora, and therefore improve the activity of the gastrointestinal tract, parietal digestion, metabolic processes and increase the body's resistance.

Indications for use

Bifidumbacterin is used to normalize the microbiocenosis of the gastrointestinal tract (correction of microflora in the intestines), stimulate the functional activity of the digestive system, for the prevention of nosocomial infections in hospitals and maternity hospitals, and also has detoxifying properties.

Bifidumbacterin is prescribed to both adults and children for the treatment of the following diseases:

• chronic constipation;
• bacterial colpitis and vaginosis;
• intestinal dysbiosis, including for prophylactic purposes during treatment with hormones, antibiotics, non-steroidal anti-inflammatory drugs, chemotherapy or radiation therapy, stress;
• intestinal infections of unknown origin and food toxic infections;
• allergic reactions accompanied by dysbiosis;
• acute intestinal infections (rotavirus infection, salmonellosis, shigellosis, staphylococcal enterocolitis);
• intestinal dysbiosis, which is caused by various diseases, including those that affect the digestive tract (pancreatitis, chronic diseases of the biliary tract and liver, cholecystitis, etc.);
• malabsorption syndromes;
• dysbacteriosis in bronchitis, pneumonia, inflammatory diseases of the urogenital tract;
• for the correction of intestinal microflora in people with pathologies of the intestines, pancreas or liver in the preoperative period or after operations.

Bifidumbacterin is also used for the prevention of:

• dysbacteriosis in children and adults who often suffer from acute respiratory viral infections;
• mastitis in nursing mothers who are at risk.

In the treatment of children it is used for infectious diseases, including pneumonia or purulent-septic processes, and many others (rickets, anemia, allergic diathesis, malnutrition, early transfer of children from mother's milk to artificial nutrition or donor milk).

Instructions for use and dosage

Bifidumbacterin is taken orally with meals. It should be mixed with liquid food, preferably fermented milk or 50 ml of warm water, or with breast milk.

• For preventive purposes: adults and children over three years of age are prescribed two sachets of bifidumbacterin up to two times a day, children from six months old one sachet up to twice a day, and infants up to six months a sachet once a day. Drink for about three weeks, can be repeated two to three times a year.
• For treatment: children over 7 years of age and adults are prescribed two sachets three to four times a day; children from three to seven - one sachet 3-5 times a day; from six months to three years - three to four times a day, one sachet; for children up to six months - 2-3 times a day, one sachet, if necessary, from 2-3 days to six times a day. Duration is three to four weeks, then repeated after a month.
• For acute intestinal infections: a therapeutic dose of bifidumbacterin is used, the course is five to seven days.
• For the prevention of mastitis: used externally half an hour before feeding, moisten a sterile swab in the drug solution and treat the nipples and areolas of the breasts, treat for 5 days. The solution is prepared from 1 sachet, which should be dissolved in warm water (10-15 ml).
• In gynecology: a tampon soaked in a solution of the drug is inserted intravaginally for two to three hours, the course lasts 8-10 days. The solution requires 2 sachets of the drug and warm water (15-20 ml).

Contraindications

Individual intolerance to the drug. Prescribe with caution to children who have lactose intolerance.

The product normalizes the intestinal microflora due to the introduction of live bifidobacteria, which have high activity against pathogens. Refers to probiotics. Taking the medicine helps normalize digestion, eliminate intestinal dysbiosis after antibiotics and improve nonspecific immunity.

Compound

The medicine includes dry microbial biomass containing:

• live bifidobacteria that make up the normal intestinal microflora;
• lactose, which promotes the growth of these microorganisms.

1 dose of the drug contains at least 107 CFU of lyophilized bifidobacteria.

Release form

There are several types of medication. Their main difference is in their names, which include the word bifidobacterin, and content active component. Varieties include:

• Multi-1, Multi-2, Multi-3;
• 1000 (more details) - a synbiotic containing, in addition to bifidobacteria, lactulose, acting nutrient for microflora;
• forte - additionally contains a sorbent (activated carbon), which ensures the release of bacteria along the entire length of the intestine, promotes the binding and removal of toxic substances. You can find out more about the drug.

Multi varieties are designed for children of different ages.

Dosage forms of the drug:

• rectal suppositories for children;
• vaginal and rectal suppositories for adults (more details);
• liquid concentrate for oral administration (more details);
• lyophilisate for preparing a solution;
• dry powder for preparing a solution (Forte, Multi-1 and 2);
• capsules (Multi-2 and 3, forte);
• (1000).

Bifidumbacterin is available in all of the above forms, except for powder for preparing a solution.

The number of bifidobacteria is indicated in doses. The instructions for use indicate under what conditions what number of doses should be taken. Tablets and suppositories contain 1 dose of the drug, other packaging - 5.

Capsules

The body is white, the lid is blue. Contains gelatin. Light gray to dark gray powder with black charcoal particles. There may be beige inclusions with a faint sour milk odor.

Packed in jars made of polymeric materials are 10, 18 or 30 capsules, each of which contains 5 doses.

Solution

In the form of a liquid concentrate, the drug contains a milky hydrolyzate liquid populated with bifidobacteria. The substance is opaque, sometimes with a loose sediment. The color is light beige. The taste is sour.

It is supplied for sale in glass medical containers with a volume of up to 100 ml.

To prepare a suspension, the drug is diluted using a lyophilisate. There are 5 doses in a bottle, 10 packs in a cardboard box.

Powder

Available in sachets of aluminum foil laminated with polyethylene, 5 doses each. There are 30 pcs in a pack.

Candles

White cylindrical suppositories. Packaged in blister packs of 10 pcs. 1 cardboard box contains 1 such package.

pharmachologic effect

Live bifidobacteria act on a number of pathogenic and opportunistic microorganisms:

• some types of yeast-like fungi;
• shigella;
• staphylococci;
• enteropathogenic Escherichia coli.

The drug promotes:

• improving metabolic activity;
• normalization of the functioning of the gastrointestinal tract;
• improving immunity;
• balancing the vaginal microflora;
• restoration of beneficial microorganisms of the intestinal tract.

Pharmacokinetics and pharmacodynamics

The probiotic has a local effect without being absorbed from the gastrointestinal tract.

Indications for use

The medication is prescribed to patients for the following conditions and pathologies:

• transfer of children to artificial feeding in infancy;
• prolonged intestinal dysfunction, incl. due to the development of dysbacteriosis;
• chronic inflammatory diseases of the gastrointestinal tract;
• acute intestinal infections;
• dysbiosis.

In complex therapy it is used for patients with sepsis and pneumonia. In women, it is used for the sanitation of the genital tract, preparation for childbirth in case of violation of the purity of vaginal secretion of the III-IV degree, in case of senile colpitis.

Used to prevent mastitis during breastfeeding.

The drug is also prescribed for constipation that has developed due to long-term use of antibiotics.

For complications of hemorrhoids

The use of suppositories is prescribed in complex therapy for diseases of the pelvic organs. At hemorrhoids, a fissure in the anal area helps to destroy pathogenic and conditionally pathogenic microflora, which reduces the risk of developing purulent-septic complications.

How to take Bifidumbacterin?

When using the dry preparation and the product in ampoules, adults suffering from dysbacteriosis are prescribed 5 doses 3 times a day. The duration of the course is determined by the doctor. For exacerbations, it is 5-8 days, for chronic forms of the disease - 14-21 days, up to 1 month.

Capsules, tablets, lyophilisate, powder are taken 20-30 minutes before meals or during meals. The first two forms of the drug are swallowed whole, washed down with a small amount clean water or fermented milk drink.

Before use, lyophilisate and powder are dissolved in 30-50 ml of boiled water at room temperature, fermented milk product, mixture for artificial feeding or milk.

Duration prophylactic intake- 10-15 days. Such courses can be conducted 2-3 times a year.

The duration of treatment is from 5 to 30 days. Reception is possible 2-3 times a year with intervals between them of 1 month.

The lyophilisate is diluted boiled water, after which it is taken orally or used topically on the skin or mucous membranes. If it is necessary to treat the mouth with it, use a swab moistened in a dissolved lyophilisate to treat the entire mucous membrane oral cavity. If you need to treat the nasal passages, the diluted lyophilisate is instilled with a pipette, a few drops at a time.

Duration of preventive and medicinal use liquid preparation is 2-3 weeks, if necessary, the period is increased to 2 months.

At antibacterial therapy a probiotic is prescribed from the first day of its implementation. Take 2-3 hours after the antibiotic.

The bottle with liquid concentrate is shaken before use to mix the contents. Open the lid of the container, use a syringe or measuring spoon to take the required amount.

In gynecology, adult suppositories are used, inserted into the vagina. For thrush, the drug prevents the uncontrolled proliferation of Candida fungi. It is used in complex treatment together with antifungal agents.

For diarrhea, hemorrhoids, allergies, and intestinal diseases, suppositories are used rectally.

To normalize the microbiocenosis in the intestines, the drug is prescribed after surgical interventions on the liver, pancreas, intestines. It is also used in preparation for surgical procedures.

special instructions

The drug is taken with caution in case of lactose intolerance. For getting liquid form It should not be diluted in water with a temperature exceeding 40°C. The prepared solution cannot be stored.

Probiotics that are in damaged packaging are not used for treatment. Candles that smell like rancid oil should not be used.

The drug has no effect on management vehicle, since it does not affect the speed of psychomotor reactions and concentration

Compatibility with alcohol is negative when taken together.

Use in childhood

The probiotic is used for children from 2 weeks of age in the form of lyophilisates and powders. From 1 month of age, use baby rectal suppositories. After reaching 3 years of age, they begin to take capsules.

• 1 - for children from birth to 3 years;
• 2 - from 3 to 12 years;
• 3 - from 12 to 18 years.

The dosages of capsules and powder correspond to the norms of children of different ages. The number of courses per year is 2-3 with a minimum interval between them of 1 month.

For newborns

For infants, it is better to dilute the drug in milk or in a mixture. The powder is diluted in a small container into which 30-50 ml of solvent is measured, the powder is poured into it, mixed (not necessarily until completely dissolved, just until a cloudy suspension is enough) and poured into a bottle for feeding an infant.

Multi-1 is given 20-30 minutes before feeding or immediately at the next feeding.

Pregnancy and lactation

The drug is used in late pregnancy without harm to the baby. Before birth, any form of probiotic is used. Mainly used for violation of the purity of vaginal secretions and other pathologies of the vagina.

The use of the product is allowed after childbirth and during breastfeeding.

The instructions include taking it before or during meals. The drug should not be taken after meals.

Contraindications

All forms of the drug are contraindicated in case of individual intolerance to the components. Tablets and capsules - for children under 3 years of age.

Side effects

Allergic reactions may occur.

Overdose

In patients diabetes mellitus A hypoglycemic state may occur, which is characterized by:

• allergies;
• tachycardia;
• anxiety.

Intensifying:

• tremor;
• weakness;
• sweating

The drug is temporarily discontinued. The patient is prescribed:

• crystalloid solutions;
• saluretics;
• alkalizing and antihistamines.

Mostly side effects not noted.

Interaction

No undesirable manifestations were noted when interacting with other drugs. It is necessary to observe a time gap when taking with antibiotics. When taken with vitamins, the effect of the probiotic is enhanced.

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